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Epidurals and spinal anesthetics safer than previously reported

The largest ever prospective study [1,2] into the major complications [3] of epidurals and spinal anaesthetics published in the British Journal of Anaesthesia today (Monday 12 January 2009) concludes that previous studies have over-estimated the risks of severe complications of these procedures.

12 Jan 2009

Work pressure linked to stroke in Japanese men

Japanese men in high-stress jobs appear to have an increased risk of stroke compared with those in less demanding positions, according to a report in the January 12 issue of Archives of Internal Medicine.

12 Jan 2009

Researchers solve structure of key Ebola protein

Research led by Iowa State University scientists has them a step closer to finding a way to counter the Ebola virus.

12 Jan 2009

New cellular clues to understanding cancer

In the 13th January print edition of the journal Current Biology, Instituto Gubenkian de Ciencia researchers provide insight into an old mystery in cell biology, and offer up new clues to understanding cancer.

12 Jan 2009

HRT linked to brain shrinkage, but not lesions

Two new studies show that commonly prescribed forms of postmenopausal hormone therapy may slightly accelerate the loss of brain tissue in women 65 and older beyond what normally occurs with aging.

12 Jan 2009

GSK and XenoPort resubmit NDA for Solzira in restless legs syndrome

GlaxoSmithKline and XenoPort, Inc. announced today that GSK has resubmitted the New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) requesting approval of Solzira(TM) (gabapentin enacarbil) Extended Release Tablets for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS).

12 Jan 2009

Glaucoma may be linked to reading impairment in older adults

Glaucoma appears to be associated with slower spoken reading and increased reading impairment in older adults, according to a report in the January issue of Archives of Ophthalmology.

12 Jan 2009

Less than seven hours of sleep may mean more colds

Individuals who get less than seven hours of sleep per night appear about three times as likely to develop respiratory illness following exposure to a cold virus as those who sleep eight hours or more, according to a report in the January 12 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

12 Jan 2009

FORMA Therapeutics to collaborate with Novartis on inhibitors

FORMA Therapeutics has announced that it has entered into a license and option agreement through the Novartis Option Fund.

12 Jan 2009

New hope for transplant recipients and AIDS patients

A researcher from the Université de Montréal and the Maisonneuve-Rosemont Hospital has discovered the mechanism that prevents the regeneration of CD4+ T lymphocytes, which are white cells that are required for the proper functioning of the immune system.

12 Jan 2009

Discovery of mechanism that may explain Parkinson's and other neurological disorders

Studying just eight families worldwide, the international team of researchers have discovered a genetic defect that results in profound depression and parkinsonism in a disorder known as Perry syndrome.

12 Jan 2009

Diabetes associated with different types of brain injury in patients with dementia

Patients with dementia and diabetes appear to display a different pattern of injuries in their brains than patients with dementia but without diabetes, according to an article posted online today that will appear in the March print issue of Archives of Neurology.

12 Jan 2009

Bristol-Myers Squibb and ZymoGenetics to collaborate on hepatitis C compound

Bristol-Myers Squibb and ZymoGenetics, Inc. have announced a global collaboration for PEG-Interferon lambda, a novel type 3 interferon currently in Phase Ib development for the treatment of Hepatitis C, and its related development program.

12 Jan 2009

Blood mercury levels associated with income, ethnicity and coastal areas

A new study reveals that women living in coastal areas and in the Northeast U.S. were more likely than other women to have blood mercury (BHg) concentrations exceeding levels of concern, as reported in the January 2009 issue of the peer-reviewed journal Environmental Health Perspectives (EHP).

12 Jan 2009