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Potential drug target identified for diabetes by studying novel gut-brain-liver circuit

Scientists at the Toronto General Hospital Research Institute have discovered a novel signaling pathway between three organs - the gut, the brain, and the liver - which lowers blood sugar when activated.

10 Apr 2008

Discovery of process behind heart muscle contraction

Researchers from the University of Pittsburgh and the University of Chicago were able to control heart muscle function in a new way after discovering the previously unknown role of two enzymes in heart muscle contraction, as detailed in the April 11 cover story of the Journal of Biological Chemistry.

10 Apr 2008

Personality disorders cause emotional reactions in staff

A study published in the open access journal BMC Psychiatry suggests that the way in which professional care workers respond emotionally to substance abuse patients with personality disorders depends on the type of disorder.

10 Apr 2008

Omega-3 intake during the last months of pregnancy boosts an infant's development

A study supervised by Universite Laval researchers Gina Muckle and Eric Dewailly reveals that omega-3 intake during the last months of pregnancy boosts an infant's sensory, cognitive, and motor development.

10 Apr 2008

Obesity costs U.S. companies $45 billion annually in medical expenditures and work loss

The rate of obesity in the United States has doubled in the last 30 years, and those extra pounds weigh on companies' bottom lines, according to a new report from The Conference Board.

10 Apr 2008

New devices and research for mechanical circulatory support in pediatrics

New devices and research for mechanical circulatory support in pediatrics from the National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI) Pediatric Circulatory Support Program will be discussed at the International Society for Heart and Lung Transplantation (ISHLT) 28th Annual Meeting and Scientific Sessions.

10 Apr 2008

Molecule delivery method improves stem cell differentiation

Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease.

10 Apr 2008

Module map links embryonic stem cells and cancer stem cells

A new study suggests that a genetic fingerprint associated with normal embryonic stem cells may be important for the development and function of cancer stem cells.

10 Apr 2008

Method to deliver molecules within embryonic stem cells improves differentiation

Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease.

10 Apr 2008

Methamphetamine use in pregnancy changes learning ability of the offspring

Studies have suggested that infants exposed to methamphetamines while in the womb can suffer irreversible brain damage, although the exact effects of these drugs during pregnancy have been hard to pinpoint due to many other negative behaviors that often occur in meth users.

10 Apr 2008

Methamphetamine addiction mechanism discovered

Researchers have identified, for the first time, long-term changes in the brain circuitry of methamphetamine-addicted mice that can explain why the craving of addiction is so stubborn and long-lived.

10 Apr 2008

Manipulating the immune system like a parasite

One day it may be possible to mimic the tactics used by parasites to trick the body into accepting transplanted tissues or organs.

10 Apr 2008

Keeping fit delays biological aging by up to 12 years

Maintaining aerobic fitness through middle age and beyond can delay biological ageing by up to 12 years and prolong independence during old age, concludes an analysis published ahead of print in the British Journal of Sports Medicine.

10 Apr 2008

Looping genes may hold a key to understanding breast cancer

Another piece of the puzzle that is breast cancer has been found by University of Queensland researchers.

10 Apr 2008

Landmark study to improve osteoporosis care standards worldwide

Nearly 60,000 women aged 55 years and older have enrolled in a landmark, multi-national study that will focus on the management of osteoporosis across the globe.

10 Apr 2008

Kidney cancer deaths show overall decrease in Europe

Overall deaths from kidney cancer have now fallen across Europe after peaking in the early 1990s, according to a detailed analysis of mortality rates for 32 countries published in the urology journal BJU International.

10 Apr 2008

Housework boosts mental health

Just 20 minutes of any physical activity, including housework, in a week is enough to boost mental health, reveals a large study published ahead of print in the British Journal of Sports Medicine.

10 Apr 2008

Researchers identify gene involved in blood stem cell replication, movement

Researchers at the Joslin Diabetes Center have identified a gene that is responsible for the division and movement of marrow-derived, blood-forming stem cells, a finding that could have major implications for the future of bone marrow and blood cell transplantation.

10 Apr 2008

Carotid endarterectomy versus carotid stenting for clogged neck arteries

Like horses running down the long stretch of a race track, two different artery-opening treatments appear to be running neck-and-neck when it comes to preventing stroke among people with clogged neck arteries and other health problems.

10 Apr 2008

Research using human embryonic stem cells reveals earliest step in human development

Researchers at Johns Hopkins have uncovered the molecular underpinnings of one of the earliest steps in human development using human embryonic stem cells.

10 Apr 2008