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Malaria - the left hand doesn't know what the right hand is doing!

The World Health Organisation (WHO) is quite rightly patting itself on the back because it has persuaded as many as 13 drug companies to abandon the marketing and promotion of monotherapy in the treatment of Malaria.

16 May 2006

New compound shows unique potency against cancer cell proliferation

By determining how a class of compounds blocks signaling in cells, University of California, San Francisco (UCSF) scientists have identified what is perhaps the most potent drug candidate yet against a highly lethal kind of brain tumor.

16 May 2006

Exercise protects against skin cancer

While doctors and scientists have long agreed that physical activity has health benefits, Rutgers cancer researcher Allan Conney and his New Jersey colleagues have found that exercise can even protect against skin cancer.

16 May 2006

German scientists synthesize new compound that reduces stroke damage

A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.

16 May 2006

Who should get influenza vaccine?

An American flu pandemic would present difficult and tragic choices: As many as 90 million people might become sick, and widespread shortages of vaccine would likely leave more than 90 percent of the population unprotected in the pandemic's first year.

16 May 2006

3D map of the structure of the enzyme D-xylose isomerase

An innovative collaboration among scientists at Los Alamos National Laboratory, Fox Chase Cancer Center and the University of Tennessee has successfully applied neutron diffraction to create a three-dimensional map of the structure of the enzyme D-xylose isomerase.

16 May 2006

Researchers discover naturally occurring growth factor that stimulates regeneration of injured nerve fibers in the central nervous system

Researchers at Children's Hospital Boston have discovered a naturally occurring growth factor that stimulates regeneration of injured nerve fibers (axons) in the central nervous system.

16 May 2006

Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia

Long-term therapy with some antiepileptic drugs and antibiotics can cause osteomalacia, a condition marked by softening of the bones that is usually the result of vitamin D and calcium deficiency.

16 May 2006

SOX2 neural stem cell gene important in eye development

Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place.

16 May 2006

Signaling pathways in immune cells may lead to novel HIV treatment

New research on signaling pathways in immune cells bolsters evidence of connections between the central nervous system and the immune system.

16 May 2006

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Scientists have identified a new molecule that inhibits proliferation of a broad range of lethal malignant glioma cells in vitro and in vivo.

16 May 2006

Common genetic variation makes some people more susceptible to coronary heart disease

Caucasians who carry this polymorphism, named K55R, were at significantly higher risk of coronary heart disease, independent of other risk factors, like cigarette smoking, diabetes, and hypertension.

16 May 2006

A review of percutaneous kyphoplasty

A procedure that fills in fractured vertebrae with injected cement has not been shown to improve a person's back pain or quality of life, according to a new analysis of studies.

16 May 2006

Diabetes troubles Australia

The Australia-wide study was conducted by the International Diabetes Institute over the last 15 months and is the first to have measured how many new cases of these diseases occur in Australia annually.

16 May 2006

Inducing labor increases risk of developing chorioamnionitis

Women who have their labor induced or are given medication to stimulate contractions are at greater risk of developing chorioamnionitis

16 May 2006

Low affinity analogs of thyrotropin-releasing hormone are super-agonists

Chemical knockoffs resembling a key thyroid-related hormone are, in certain cases, more effective than the real thing at activating the target receptor.

16 May 2006

BMI standards for younger adults may not be appropriate for people in their 80s and 90s

If you're more than 80 years old, carrying a few extra pounds might not be such a bad idea. In fact, it may be beneficial.

16 May 2006

Access to emergency hormonal contraception from community pharmacists and family planning clinics

Pharmacies who provide fast and convenient access to the morning-after pill could be helping to prevent 10 per cent more unwanted pregnancies, according to a study in the latest British Journal of Clinical Pharmacology.

16 May 2006

First animal model that mimics human head and neck cancer

An Oregon Health & Science University Cancer Institute research laboratory has developed a novel mouse model designed specifically to study the often devastating head and neck squamous cell cancers.

16 May 2006

Exercise, diet may protect against colorectal cancer

Voluntary exercise and a restricted diet reduced the number and size of pre-cancerous polyps in the intestines of male mice and improved survival, according to a study by a University of Wisconsin-Madison research published in the journal Carcinogenesis.

16 May 2006