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Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Protective genetic variant shields Black Americans from kidney disease risk

Many Black Americans who are thought to have a high risk of developing kidney disease possess a protective genetic variant that nullifies the extra risk, a new study from Columbia researchers has found.

12 Dec 2023

OHSU study sheds light on ubiquitin modification during bacterial infection

New research from Oregon Health & Science University could one day lead to therapies that prevent or treat diseases and infections tied to a protein that's found in all human cells.

12 Dec 2023

Simple eye test spots patients at risk for postoperative cognitive dysfunction

Identifying an older patient who is at risk for post-operative cognitive dysfunction might be done in the blink of an eye – literally.

12 Dec 2023

U.S. veterans' study reveals key insights into Long COVID and protective role of vaccination

Study examines the clinical characteristics and trends of post-COVID-19 condition (PCC) in U.S. veterans, showing the protective effect of vaccination and the need for precise symptom documentation for effective research and clinical care.

12 Dec 2023

Stem cell therapy trial shows promise for regenerative treatment of heart failure

Stem cell-based therapy improved quality of life for patients with advanced heart failure, Mayo Clinic researchers and international collaborators discovered in a late-stage multinational clinical trial.

12 Dec 2023

Researchers find powerful combo weapon against aggressive lymphoma

The targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (PFS) and achieved an overall remission rate in 82% of patients with relapsed/refractory mantle cell lymphoma (MCL), according to researchers at The University of Texas MD Anderson Cancer Center. Results from the Phase III SYMPATICO trial were presented at the 2023 American Society of Hematology (ASH) Annual Meeting.

12 Dec 2023

Brainoware: A breakthrough AI approach using brain organoids for advanced computation

Study in Nature Electronics introduces "Brainoware," an innovative AI hardware approach using brain organoid neural networks for complex tasks like speech recognition and nonlinear dynamic predictions, demonstrating significant potential in AI development.

12 Dec 2023

Unmasking the barriers faced by women veterans in seeking mental health support

Issues of identity, male-dominated branding and apprehension that their needs will go unmet are among the reasons women are not accessing veterans' mental health support, according to new research being discussed today (Wednesday, 13 December) at a conference in Cambridge.

12 Dec 2023

PCOS patients can achieve same birth rates with treatment

Researchers from The University of Queensland have found that women with polycystic ovary syndrome (PCOS) respond well to fertility treatments and have the same birth rate as women without the condition.

12 Dec 2023

Tat-heat shock protein 10 could rejuvenate aging brains

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, "Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampus."

12 Dec 2023

UK Biobank data shows dose-dependent link between smoking and brain shrinkage

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis.

12 Dec 2023

Loneliness linked to increased mortality risk in older adults, study finds

Study reveals that cumulative loneliness significantly increases mortality risk among middle-aged and older adults in the U.S., emphasizing the need for interventions to combat social isolation.

12 Dec 2023

AI model detects atrial fibrillation risk based on subtle ECG variations

A new artificial intelligence (AI) model designed by Scripps Research scientists could help clinicians better screen patients for atrial fibrillation (or AFib) - an irregular, fast heartbeat that is associated with stroke and heart failure.

12 Dec 2023

Tirzepatide shows success in maintaining weight loss in obese adults

Study finds that the anti-obesity medication tirzepatide effectively maintains weight loss in obese adults, offering a promising approach to managing obesity and related health complications.

12 Dec 2023

Study highlights the necessity to refine the design of randomized cancer drugs trials in China

More than one-eighth of the randomized trials of cancer drugs seeking regulatory approval in China in recent years used inappropriate controls to test the effectiveness and safety of the drugs, according to a new study published December 12th in the open access journal PLOS Medicine by Professor Xiaodong Guan of Peking University, China, and colleagues.

12 Dec 2023

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Published in The Lancet's eBioMedicine, 76 healthy adults from Melbourne, aged 18 to 64 who were previously vaccinated with licensed SARS-CoV-2 vaccines, were randomized to receive a fourth dose of a novel protein vaccine, mRNA vaccine or placebo.

12 Dec 2023

Liquid biopsy may offer new tools for personalized immunotherapy in lung cancer

Using a "liquid biopsy" to study genetic material from tumors shed into the bloodstream together with immune cells could help clinicians predict which patients with advanced lung cancers are responding to immunotherapies and which patients may develop immune-related side effects several months later, according to research directed by investigators at the Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and Allegheny Health Network Cancer Institute in Pittsburgh.

12 Dec 2023

Evaluating the health risks associated with dietary exposure to metals

The problem of foodborne metal contamination has taken on new urgency, thanks in part to a 2021 US Congressional Report detailing high levels of metals found in infant food pulled off grocery shelves.

12 Dec 2023

Self-monitoring shows promise in managing high blood pressure and pre-eclampsia in pregnancy

Study suggests that self-monitoring of blood pressure may aid in the early detection and management of high blood pressure and pre-eclampsia in high-risk pregnancies, offering a potential shift in prenatal care strategies.

12 Dec 2023