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Pharmaceutical industry faces multiple challenges - future lies in drug pipeline sustainability

High clinical development costs coupled with declining drug discovery success rates are causing productivity levels to fall in the global pharmaceuticals industry. The imminent patent expiry of several major blockbuster drugs and the related rise of cheaper generic alternatives is further exacerbating the situation.

25 May 2005

Measuring hormone procalcitonin cuts antibiotic use in half in pneumonia patients

Measuring a hormone in the blood can help doctors greatly reduce the number of days pneumonia patients have to take antibiotics to cure their infection, according to a study to be presented at the American Thoracic Society International Conference.

25 May 2005

Female lung transplant recipients more likely to suffer from primary graft dysfunction

Female lung transplant recipients are significantly more likely to suffer from a type of injury to the transplanted lung called primary graft dysfunction than male lung transplant patients, according to a study presented at the American Thoracic Society International Conference.

25 May 2005

Bladder capacity rarely changes as you age

The idea that your bladder shrinks as you get older may be nothing more than an old wives' tale according to a University of Pittsburgh study. The feeling may, however, signal a treatable underlying condition.

25 May 2005

Laughter brings on asthma

More than half of people with asthma report that their symptoms are brought on by laughter, according to a study to be presented at the American Thoracic Society International Conference on May 24.

25 May 2005

Study shows using expanded critera donors is safe

Patients who had received livers from hepatitis B virus core antibody (HBcAb) positive (indicates prior exposure to hepatitis B) and/or hepatitis C virus (HCV) positive donors had similar graft and patient survival compared to patients who received HBcAb negative or HCV negative livers, according to a study by the University of Pittsburgh's Thomas E. Starzl Transplantation Institute.

25 May 2005

Researchers find link between highways and breathing problems in kids

Children living close to a major road are significantly more likely to have asthma than children who live farther away, according to study findings presented today at the American Thoracic Society International Conference.

25 May 2005

Ceramide can be administered through the blood stream to target and kill cancer cells

A Penn State College of Medicine study shows for the first time in an animal model that ceramide, a naturally occurring substance that prevents the growth of cells, can be administered through the blood stream to target and kill cancer cells.

25 May 2005

Patients disfigured in traumatic incidents may experience significant social and behavioral problems

Patients disfigured in traumatic incidents are much more likely to suffer post traumatic stress disorder, unemployment, marital problems, binge drinking and depression, according to a study by Yale School of Medicine researchers.

25 May 2005

Patients approaching the end of life can significantly reduce their depression symptoms and improve their sense of spiritual well-being

"Patients with serious medical conditions frequently suffer psychological, relational, and spiritual distress that is being inadequately addressed by modern health care," writes first author Douglas Miller, M.D., Indiana University School of Medicine professor of medicine, Regenstrief Institute, Inc. research scientist, and associate director of the IU Center for Aging Research.

25 May 2005

Team IDs mechanism for multiplying adult stem cells

While research on human embryonic stem cells gets most of the press, scientists are also investigating the potential therapeutic uses of adult stem cells. Although less controversial, this research faces other difficulties. Adult stem cells are extremely difficult to isolate and multiply in the lab.

24 May 2005

NC3Rs announces increased funding for the 3Rs and welcomes the Nuffield Council report

The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) announces today that it has been awarded additional money from the Government.

24 May 2005

Scots confused about emergency services

Whether it's a life threatening emergency or a routine problem such as a chesty cough, research released today (Wednesday 25 May 2005) from Developing Patient Partnerships (DPP) shows that people just don't know what to do.

24 May 2005

Early-onset antisocial behaviour in children with psychopathic tendencies is largely inherited

The findings are the result of extensive research funded by the Medical Research Council, the Department of Health and the Home Office, and carried out by Dr. Essi Viding of the MRC Social, Genetic and Developmental Psychiatry Centre, within the Institute of Psychiatry, King's College London.

24 May 2005

Guidant admits, three years down the line, to a fault with internal heart defibrillator

In a very belated admission Guidant Corp., has now acknowledged that it's internal heart defibrillator has an electrical problem that caused a small fraction of the implanted devices to short-circuit.

24 May 2005

A good education makes women sleep better

According to a study done in Taiwan educated women are less likely to suffer from insomnia than their less learned counterparts, but surprisingly, their male equivalents are less likely to get a good night’s sleep if they have had the benefit of a good education.

24 May 2005

Patients on hypertension and lipid-lowering medications not sticking to prescriptions

A new study designed to look at how well patients with high blood pressure and dyslipidemia (high cholesterol levels) coped with their medication, has discovered that within six months many patients fail to take blood pressure or cholesterol medication properly.

24 May 2005

No link found between hair dyes and cancers

The growing worldwide concern about a possible link between hair dyes and some forms of cancer, which was further fuelled by one recent study showing an apparent positive relationship, prompted a European Commission safety panel to call for an urgent review.

24 May 2005

Six deaths in transplant patients now linked to rodent virus

In the latest news on the subject, experts now believe they can link at least six deaths of organ transplant patients to a rodent virus, which raises questions about whether others may have gone undetected and whether the germ also could spread through blood transfusions.

24 May 2005

Researchers discover genetic trigger that plays a key role in cancer of the oesophagus

Cancer Research UK scientists at the University of Oxford have identified a gene which plays a key role in the development of cancer of the oesophagus by triggering changes in the oesophagus lining.

24 May 2005

Medical News

Pharmaceutical industry faces multiple challenges - future lies in drug pipeline sustainability

Measuring hormone procalcitonin cuts antibiotic use in half in pneumonia patients

Female lung transplant recipients more likely to suffer from primary graft dysfunction

Bladder capacity rarely changes as you age

Laughter brings on asthma

Study shows using expanded critera donors is safe

Researchers find link between highways and breathing problems in kids

Ceramide can be administered through the blood stream to target and kill cancer cells

Patients disfigured in traumatic incidents may experience significant social and behavioral problems

Patients approaching the end of life can significantly reduce their depression symptoms and improve their sense of spiritual well-being

Team IDs mechanism for multiplying adult stem cells

NC3Rs announces increased funding for the 3Rs and welcomes the Nuffield Council report

Scots confused about emergency services

Early-onset antisocial behaviour in children with psychopathic tendencies is largely inherited

Guidant admits, three years down the line, to a fault with internal heart defibrillator

A good education makes women sleep better

Patients on hypertension and lipid-lowering medications not sticking to prescriptions

No link found between hair dyes and cancers

Six deaths in transplant patients now linked to rodent virus

Researchers discover genetic trigger that plays a key role in cancer of the oesophagus

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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