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RBM5 identified as key regulator of HOXA9 in acute myeloid leukemia

The protein HOXA9 is overexpressed in most acute myeloid leukemia (AML) cases and is associated with poor patient outcomes.

12 Jan 2024

FDA-approved drug may help to decrease pain after surgery, study finds

Researchers in the Department of Anesthesia and Perioperative Medicine at the Medical University of South Carolina (MUSC) have found that an FDA-approved drug may help to decrease pain after surgery.

12 Jan 2024

10 years of University of Kentucky's Healthy Hearts for Women takes aim at heart disease

The University of Kentucky will mark a decade of raising awareness and continuing its effort to warn women about the dangers of heart disease with the annual Healthy Hearts for Women Symposium.

12 Jan 2024

Pazopanib activity confirmed in EWSR1-NFATC2 bone sarcoma

A new case report was published in Oncoscience (Volume 10) on September 20, 2023, entitled, "Activity of pazopanib in EWSR1-NFATC2 translocation-associated bone sarcoma."

12 Jan 2024

Community health workers champion genetic literacy for minorities

Changes to DNA, known as mutations, can increase the likelihood of developing cancer. Specifically, people with mutations in their BRCA 1 and 2 genes are substantially more likely to develop hereditary breast and ovarian cancers. But how do people know if they have these mutations?

12 Jan 2024

3D nanomatrix vascular sheet model for high-throughput atherosclerosis drug testing

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

12 Jan 2024

Urinary incontinence associated with higher odds of future disability

If you are one of the 30% to 50% of women experiencing urinary incontinence, new research suggests that it could turn into a bigger health issue.

12 Jan 2024

A biological signature of desire helps explain the selective nature of pair bonds

Hop in the car to meet your lover for dinner and a flood of dopamine - the same hormone underlying cravings for sugar, nicotine and cocaine - likely infuses your brain's reward center, motivating you to brave the traffic to keep that unique bond alive.

12 Jan 2024

Drinkable, carbon monoxide-infused foam supercharges cancer therapy

Did smokers do better than non-smokers in a clinical trial for an experimental cancer treatment? That was the intriguing question that led University of Iowa researchers and their colleagues to develop a drinkable, carbon monoxide-infused foam that boosted the effectiveness of the therapy, known as autophagy inhibition, in mice and human cells.

12 Jan 2024

Researchers uncover role of persister cells in antibiotic resistance

Antibiotic overuse can lead to antibiotic resistance, but classic antibiotic resistance might not completely explain why antibiotics sometimes fail.

12 Jan 2024

Cedars-Sinai pioneers method to identify dementia patients for better care

Cedars-Sinai investigators are using electronic health records to identify hospitalized patients likely to have dementia.

12 Jan 2024

Mary Lou Retton’s explanation of health insurance takes some somersaults

Former Olympic gymnast Mary Lou Retton spoke out last week on the NBC "Today" show about what she said was a rare pneumonia that almost killed her and resulted in an expensive, monthlong hospital stay.

12 Jan 2024

Human rabies in Shanghai: Epidemiological insights for improved prevention and control

Announcing a new article publication for Zoonoses journal. Rabies is a vaccine-preventable, viral zoonotic disease caused by a lyssavirus.

12 Jan 2024

Adapting problem-solving techniques used in engineering to boost medical innovation

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) and the University of Oxford have successfully demonstrated how problem-solving techniques used in engineering, known as Innovation Enhancing Techniques, can be adapted and used to improve creativity in problem-solving when it comes to abstract problems faced in healthcare and biomedicine.

12 Jan 2024

Defective gene triggers uncontrolled immune attack in young lupus patients

A group of researchers lead by Min Ae Lee-Kirsch from the Department of Pediatrics, Medical Faculty, TUD Dresden University of Technology (Germany), studied four patients from two families who developed symptoms of SLE in the first years of life.

12 Jan 2024

Stromal cells may be useful in assessing prostate tumors' potential to spread

Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be useful in assessing these tumors' potential to spread, and may even be targets for future prostate cancer treatments, according to a study led by researchers at Weill Cornell Medicine.

12 Jan 2024

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Researchers at Tohoku University have discovered a new approach for treating lymph node metastasis. Anticancer drugs are administered directly into the LNs under ultrasound guidance (Lymphatic Drug Delivery System or LDDS) to target sentinel lymph nodes (LNs) and generate antitumor effects locally, preventing distant metastasis.

12 Jan 2024

Unequal access to cancer care persists across U.S. states due to insurance variations

A new study led by American Cancer Society (ACS) researchers shows substantial state variations in health insurance coverage, which is a strong determinant of cancer care access and survival, among newly diagnosed cancer patients in the United States.

12 Jan 2024

Artificial intelligence spots risky drinkers for safer surgery

Using artificial intelligence to scan surgery patients' medical records for signs of risky drinking might help spot those whose alcohol use raises their risk of problems during and after an operation, a new study suggests.

12 Jan 2024

AI models for mental health hit generalizability snag

Scientists from Yale and the University of Cologne were able to show that statistical models created by artificial intelligence (AI) predict very accurately whether a medication responds in people with schizophrenia.

12 Jan 2024