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Manipulating white blood cells to eliminate solid tumors

By silencing the molecular pathway that prevents macrophages from attacking our own cells, Penn Engineers have manipulated these white blood cells to eliminate solid tumors.

12 Jun 2023

Metformin shows promising antiviral activity against SARS-CoV-2

Metformin, a widely available oral medication, reduces SARS-CoV-2 viral load by 3.6-fold in outpatient trial, offering a potential treatment option. Ivermectin and fluvoxamine show no significant virologic effect.

12 Jun 2023

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Asthma is more dangerous than many people realize. An estimated 10 Americans die everyday from asthma, and the disease leads to around 439,000 hospitalizations and 1.3 million emergency room trips each year.

12 Jun 2023

Metformin reduces risk of long COVID by over 40%

Researchers discuss whether metformin, ivermectin, or fluvoxamine could reduce the risk of long COVID if administered shortly after infection.

12 Jun 2023

Police drug seizures associated with increase in fatal overdoses

For decades, efforts by police to seize illicit drugs have been a cornerstone strategy for disrupting drug markets and removing drugs from communities. But there's an unintended outcome when opioids are seized, a new study finds - increases in overdoses, including those that are fatal.

12 Jun 2023

Rising alcohol consumption in China linked to increased risk of 61 diseases

The associations between alcohol consumption and the risk of diseases in Chinese adults.

12 Jun 2023

VLA1553 vaccine candidate for chikungunya disease produces an immune response in a phase 3 trial

The VLA1553 vaccine candidate for chikungunya disease was generally well tolerated and produced an immune response in 99% (263/266) of participants, according to a phase 3 randomized controlled trial published in The Lancet.

12 Jun 2023

New study may help improve diagnosis of cognitive disability in Parkinson's disease

A few minutes of data recorded from a single electrode placed on top of the head may be sufficient to predict thinking problems, including dementia, in patients with Parkinson's disease (PD).

12 Jun 2023

Quality of life, self-esteem of healthy short youth associated with coping skills and social support

Challenging the assumption that short stature negatively impacts children and adolescents' self-esteem, a new study by researchers at Children's Hospital of Philadelphia (CHOP) has found that in otherwise healthy short youth, quality of life and self-esteem are associated with coping skills and how supported they feel and not the degree of their short stature.

12 Jun 2023

Researchers test a new way to deliver mental health therapy to people with addiction, aggressive behavior

Researchers from five colleges at Rochester Institute of Technology are testing a new way to deliver mental health therapy to people struggling with alcohol/drug addiction and aggressive behavior.

12 Jun 2023

Smartphones on desk proven to hamper student focus, even when switched off!

Smartphones impact students' attention. Experiment confirms lower cognitive performance due to smartphone presence. Study explores implications.

12 Jun 2023

Spaceflight experience alters human brain structure, posing challenges for long-term missions

Spaceflight impacts brain structure. Longer missions lead to greater ventricle expansion, especially within the first 6 months. Shorter inter-mission intervals limit ventricle recovery. Findings reveal limits and recovery capacity of the brain during spaceflight.

12 Jun 2023

Study: Weight and BMI policies by NHS are inappropriate and worsen health inequalities

Weight and body mass index (BMI) policies introduced by NHS commissioning groups in England are inappropriate and worsening health inequalities, according to a new study published in BMC Medicine today [13 June] that analyzed nearly 490,000 hip surgeries.

12 Jun 2023

Researchers identify a potential breakthrough in glioblastoma treatment

In a recently published manuscript, Howard Colman, MD, PhD, Jon M. Huntsman Presidential Professor of Neuro-Oncology and co-leader of the Neurologic Cancers Disease Center and the Experimental Therapeutics CCSG program at Huntsman Cancer Institute, identified a potential breakthrough in glioblastoma treatment.

12 Jun 2023

Chronic exposure to lead, cadmium and arsenic associated with increased risk of cardiovascular disease

Chronic exposure to low levels of lead, cadmium and arsenic through commonly used household items, air, water, soil and food is associated with an increased risk of cardiovascular disease, according to a new American Heart Association scientific statement published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

12 Jun 2023

Study provides a possible treatment option for prostate cancer resistant to hormone therapy

Prostate cancer is the most-commonly diagnosed malignancy and the second leading cause of cancer death among men in the United States.

12 Jun 2023

Rice U. postdoctoral fellow explores the link between menopause and Alzheimer’s disease

Two-thirds of the people suffering from Alzheimer's disease are women, yet most research has ignored differences between the sexes.

12 Jun 2023

First-of-its-kind prognostic blood test can better predict preeclampsia risk

For decades, doctors have typically relied on measuring blood pressure and proteins in urine to determine whether a woman will develop preeclampsia, a serious hypertensive disorder that affects roughly 2% to 8% of pregnant women worldwide.

12 Jun 2023

Thyrotropin-releasing hormone neurons play a key role in the response to fasting and weight loss

Regulation of thyroid hormone (TH) levels is a complex multilevel phenomenon. The paraventricular nucleus (PVN) of the hypothalamus (the region of the brain that controls the involuntary nervous system) has been identified as a direct regulator of thyrotropin (a hormone secreted by the pituitary gland that regulates the production of thyroid hormones).

12 Jun 2023

So-called “orphan” drugs earn pharmaceutical companies as much money as mainstream medicines

Drugs used to treat rare conditions are earning pharmaceutical companies almost as much as those marketed to the general public, according to a researcher at West Virginia University. Sean Tu, a College of Law professor found lucrative so-called "orphan" drugs earn manufacturing tax credits, have longer patent exclusivities and face easier Food and Drug Administration review.

12 Jun 2023

Medical News

Manipulating white blood cells to eliminate solid tumors

Metformin shows promising antiviral activity against SARS-CoV-2

Study suggests the role of histamine-releasing factor in severe asthma and RV-induced asthma exacerbation

Metformin reduces risk of long COVID by over 40%

Police drug seizures associated with increase in fatal overdoses

Rising alcohol consumption in China linked to increased risk of 61 diseases

VLA1553 vaccine candidate for chikungunya disease produces an immune response in a phase 3 trial

New study may help improve diagnosis of cognitive disability in Parkinson's disease

Quality of life, self-esteem of healthy short youth associated with coping skills and social support

Researchers test a new way to deliver mental health therapy to people with addiction, aggressive behavior

Smartphones on desk proven to hamper student focus, even when switched off!

Spaceflight experience alters human brain structure, posing challenges for long-term missions

Study: Weight and BMI policies by NHS are inappropriate and worsen health inequalities

Researchers identify a potential breakthrough in glioblastoma treatment

Chronic exposure to lead, cadmium and arsenic associated with increased risk of cardiovascular disease

Study provides a possible treatment option for prostate cancer resistant to hormone therapy

Rice U. postdoctoral fellow explores the link between menopause and Alzheimer’s disease

First-of-its-kind prognostic blood test can better predict preeclampsia risk

Thyrotropin-releasing hormone neurons play a key role in the response to fasting and weight loss

So-called “orphan” drugs earn pharmaceutical companies as much money as mainstream medicines

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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