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Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict — before treatment begins — how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Study reveals potential for digital technology to improve patients' asthma control

A new international study led by RCSI University of Medicine and Health Sciences has revealed significant potential for digital technology to improve asthma control for patients.

6 Apr 2023

Air pollution associated with increased risk of developing dementia

Exposure to fine particulate air pollutants (PM2.5) may increase the risk of developing dementia, according to a new meta-analysis from Harvard T.H. Chan School of Public Health.

6 Apr 2023

New machine learning model estimates optimal treatment timing for sepsis

A new machine learning model that estimates optimal treatment timing for sepsis could pave the way for support tools that help physicians personalize treatment decisions at the patient bedside, researchers say.

6 Apr 2023

Fasting diet could be the key to reducing the risk of type 2 diabetes

A fasting diet which focuses on eating early in the day could be the key to reducing the risk of developing type 2 diabetes.

6 Apr 2023

Analyzing DNA changes in the blood can improve prediction of type 2 diabetes risk

Analyzing changes to DNA in the blood can improve the ability to predict a person's risk of developing type 2 diabetes within a decade.

6 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

Different drivers lead men and women to develop obesity, study reveals

A new study from UCLA researchers finds sex-specific brain signals that appear to confirm that different drivers lead men and women to develop obesity.

6 Apr 2023

Intramuscular injection of TXA may be a potential alternative to reduce obstetric bleeding

Intramuscular administration of tranexamic acid (TXA), a drug used to target severe bleeding after childbirth, is safe and quickly reaches therapeutic concentrations in pregnant women, according to a study involving researchers from the London School of Hygiene & Tropical Medicine.

6 Apr 2023

New microfluidic technology enables reliable selection of high-quality sperm for IVF success

Scientists have developed new technology to help couples undergoing in-vitro fertilization (IVF) due to male fertility problems to increase their chances of success in having a baby.

6 Apr 2023

Research opens the door to new approaches for tackling antibiotic-resistant TB

University of Otago researchers have discovered new ways to treat antibiotic-resistant strains of tuberculosis (TB), opening the door to new approaches for tackling the disease that kills about 4,000 people a day.

6 Apr 2023

Obesity driven by genetic factors linked to lower risk of cardiovascular disease

The risk of developing cardiovascular disease is lower in people with obesity who have a genetic predisposition for high BMI than people with obesity influenced mainly by environmental factors such as lifestyle, researchers from Karolinska Institutet report in eClinical Medicine.

6 Apr 2023

Obstructive sleep apnea can cause early cognitive decline even in patients without co-morbidities

Obstructive sleep apnea (OSA) is a potentially dangerous condition. During sleep, the throat muscles of people with OSA relax and block the airflow into the lungs, so that they repeatedly stop breathing.

6 Apr 2023

World Health Day: Giving Universal Health Coverage a Platform

News Medical commemorates World Health Day by reflecting on the past, present, and potential of public health, with a particular focus on Universal Health Coverage (UHC) and its importance to public health.

6 Apr 2023

Study examines the causal role of insomnia symptoms on 11,409 health related-symptoms

Researchers performed Mendelian randomization phenome-wide association study of insomnia symptoms using 11,409 outcome variables.

6 Apr 2023

How does mortality due to heat and cold vary across European urban areas?

Researchers comprehensively assessed the mortality impact of non-optimal temperatures in European cities.

6 Apr 2023

How does increased family mealtime duration affect children's fruit and vegetable intake?

Researchers evaluated the effect of extending the family mealtime duration on fruit and vegetable intake in children.

6 Apr 2023

Are hypertension and blood pressure change in early adulthood associated with late-life brain health, and is there variation by sex?

Researchers assessed whether blood pressure changes during early adult life impacted neuroimaging biomarkers.

6 Apr 2023

Global antimicrobial resistance: socioeconomic factors play an underappreciated role in the spread

Researchers investigated the association between rates of antimicrobial resistance in animals and humans and environmental, socioeconomic, and anthropogenic indicators.

6 Apr 2023

Medical News

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

Study reveals potential for digital technology to improve patients' asthma control

Air pollution associated with increased risk of developing dementia

New machine learning model estimates optimal treatment timing for sepsis

Fasting diet could be the key to reducing the risk of type 2 diabetes

Analyzing DNA changes in the blood can improve prediction of type 2 diabetes risk

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Different drivers lead men and women to develop obesity, study reveals

Intramuscular injection of TXA may be a potential alternative to reduce obstetric bleeding

New microfluidic technology enables reliable selection of high-quality sperm for IVF success

Research opens the door to new approaches for tackling antibiotic-resistant TB

Obesity driven by genetic factors linked to lower risk of cardiovascular disease

Obstructive sleep apnea can cause early cognitive decline even in patients without co-morbidities

World Health Day: Giving Universal Health Coverage a Platform

Study examines the causal role of insomnia symptoms on 11,409 health related-symptoms

How does mortality due to heat and cold vary across European urban areas?

How does increased family mealtime duration affect children's fruit and vegetable intake?

Are hypertension and blood pressure change in early adulthood associated with late-life brain health, and is there variation by sex?

Global antimicrobial resistance: socioeconomic factors play an underappreciated role in the spread

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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