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T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

Second-line treatment with trastuzumab deruxtecan (T-DXd) led to significantly longer overall survival compared with trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer, according to updated results from the DESTINY-Breast03 phase III clinical trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

T-DXd shows high efficacy in HER2-positive breast cancer patients previously treated with T-DM1

Compared with capecitabine-based regimens, trastuzumab deruxtecan (T-DXd) led to higher response rates and longer survival in the third-line setting for patients with HER2-positive metastatic breast cancer previously treated with trastuzumab emtansine (T-DM1), according to results from the phase III DESTINY-Breast02 trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

HIV transmission from mother to child can be stopped with modern antiviral drugs

Antiviral drugs almost completely reduce the risk of mothers passing on HIV infection to their children, even in a low-income country with a high HIV incidence such as Tanzania, according to a new study in The Lancet HIV by researchers from Karolinska Institutet.

7 Dec 2022

Cancer immunotherapies can become more potent depending on the time of day

Scientists from the UNIGE and LMU show that the anti-tumor activity of the immune system - and the effectiveness of cancer immunotherapies - depends on the time of day.

7 Dec 2022

Wearable technology could improve doctors' ability to administer precise medication doses

For some of the powerful drugs used to fight infection and cancer, there's only a small difference between a healing dose and a dose that's large enough to cause dangerous side effects.

7 Dec 2022

Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

Researchers reported the immunogenicity, efficacy, and safety of the MVA-BN (modified vaccinia Ankara-Bavarian Nordic)-RSV (respiratory syncytial virus) vaccine against RSV-A (RSV subtype A) Memphis 37b strain in a human challenge trial.

7 Dec 2022

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

People with diabetes are benefiting from advances in medications and technologies to lower their risk of hypoglycemia, according to a Clinical Practice Guideline issued today by the Endocrine Society.

7 Dec 2022

Study allows people with type 2 diabetes to choose their own medication

A large-scale new study offers a new approach to treating type 2 diabetes - that puts patients in charge of their own medication. The Trimaster study is the first to allow people with type 2 diabetes to choose their own medication, after trying three different drugs in succession.

7 Dec 2022

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Study identifies characteristics linked with higher likelihood of post COVID-19 condition diagnosis

Many studies have described a variety of long-term effects of COVID-19, with symptoms including fatigue and malaise, breathing difficulties, and cognitive problems, often referred to as post COVID-19 condition or long COVID.

7 Dec 2022

What was the SARS-CoV-2 seroprevalence among US adults during 2021 and 2022?

In a recent Morbidity and Mortality Weekly Report (MMWR), the United States Center for Disease Control and Prevention (U.S.-CDC) published the preliminary results of the National Health and Nutrition Examination Survey (NHANES) for August 2021–May 2022.

7 Dec 2022

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Researchers at Mass Eye and Ear and Northeastern University have discovered a previously unidentified immune response inside the nose that fights off viruses responsible for upper respiratory infections.

7 Dec 2022

Researchers explore the correlation between the dynamic shedding pattern of SARS-CoV-2 and viral load

Researchers attempted to establish an association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load, indicating its ribonucleic acid (RNA) levels, and the presence of infectious virions.

7 Dec 2022

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

Researchers identified risk factors for and the prevalence of persistent pulmonary tissue alterations among hospitalized coronavirus disease 2019 (COVID-19) patients.

7 Dec 2022

LabVantage Solutions Launches Version 8.8 of its Flagship LIMS Platform

LabVantage Solutions, Inc., the leading provider of laboratory informatics solutions and services, including purpose-built LIMS solutions that allow labs to go live faster and at a lower total cost, today announced the launch of version 8.8 of its industry-leading LabVantage LIMS platform.

From LabVantage Solutions 7 Dec 2022

Owlstone Medical Presents Breath Biopsy® VOC Atlas

Owlstone Medical has embarked on an exciting project to better understand the diversity of molecules in a given breath sample

From Owlstone Medical Ltd 7 Dec 2022

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

A newly updated clinical guideline from the American Society for Radiation Oncology provides recommendations on the use of radiation therapy and systemic therapy after surgery to treat patients with endometrial cancer.

7 Dec 2022

Study: People with higher levels of vitamin D in the brain have better cognitive function

An estimated 55 million people worldwide live with dementia, a number that's expected to rise as the global population ages.

7 Dec 2022

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Among premenopausal women with hormone receptor (HR)-positive, early-stage breast cancer enrolled in the SOFT trial, those with a high score on a genomic assay called Breast Cancer Index (BCI) had increased risk of distant recurrence, and those with low BCI benefited more from the addition of ovarian suppression therapy to endocrine therapy after 12 years of follow-up, according to data presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.

7 Dec 2022

Grenova Earns ISO 9001:2015 and ISO 13485:2016 Certification as Part of Its Mission to Manufacture Green Technology

Grenova, creator of the laboratory industry’s only patented technology for washing and reusing plastic consumables, announced today that it has earned ISO 9001:2015 and ISO 13485:2016 certification as part of the company’s mission to make laboratories around the world sustainable, resilient, cost-effective, and highly efficient.

From Grenova 7 Dec 2022

Medical News

T-DXd leads to longer overall survival in HER2-positive metastatic breast cancer patients than T-DM1

T-DXd shows high efficacy in HER2-positive breast cancer patients previously treated with T-DM1

HIV transmission from mother to child can be stopped with modern antiviral drugs

Cancer immunotherapies can become more potent depending on the time of day

Wearable technology could improve doctors' ability to administer precise medication doses

Researchers share results of MVA-BN-respiratory syncytial virus vaccine human challenge trial

New Clinical Practice Guideline offers recommendations to manage hypoglycemia in people with diabetes

Study allows people with type 2 diabetes to choose their own medication

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Study identifies characteristics linked with higher likelihood of post COVID-19 condition diagnosis

What was the SARS-CoV-2 seroprevalence among US adults during 2021 and 2022?

Study reveals biological mechanism to explain why respiratory viruses spike in colder seasons

Researchers explore the correlation between the dynamic shedding pattern of SARS-CoV-2 and viral load

What is the prevalence of pulmonary tissue injury among hospitalized COVID-19 patients?

LabVantage Solutions Launches Version 8.8 of its Flagship LIMS Platform

Owlstone Medical Presents Breath Biopsy® VOC Atlas

New ASTRO guideline provides recommendations on the use of radiation therapy for endometrial cancer

Study: People with higher levels of vitamin D in the brain have better cognitive function

Genomic assay can help identify breast cancer patients who may benefit from ovarian suppression therapy

Grenova Earns ISO 9001:2015 and ISO 13485:2016 Certification as Part of Its Mission to Manufacture Green Technology

Advancing Menopause Care: Non-Hormonal Treatments for Vasomotor Symptoms

Building quality into drug development for safer, faster medicines

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

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