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Satisfying relationships in mid-life associated with lower risk of multimorbidity in older age

Satisfying relationships in mid-life with partners, friends, or work colleagues are linked to a lower risk of accumulating multiple long term conditions in older age—at least among women—suggests research published in the open access journal General Psychiatry.

22 Feb 2023

First phase I trial of intravenous mistletoe extract to treat advanced cancer

Mistletoe extract has been widely used to support cancer therapy and improve quality of life, but there has been a lack of clinical trials and data to support its use.

22 Feb 2023

Scientists identify mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

22 Feb 2023

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

Study links obesity with 21 Alzheimer's disease-related genes

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

22 Feb 2023

Monitoring the presence of bovine meat and milk factor protein expression may help identify people at risk of colorectal cancer

Bovine meat and milk factors (BMMFs) - initially identified by de Villiers et al. in 2014 - represent a class of infectious agents in beef and cow's milk that have been linked to the development of cancer.

22 Feb 2023

Association between sleep disorders and sleep-wake disturbance with MACE or all-cause mortality in the post-stroke population

Researchers assessed the association between post-stroke sleep disturbances and recurrent cardiovascular events.

22 Feb 2023

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

22 Feb 2023

Analysis examines which non-opioid drugs are best for treating acute low back pain

Acute low back pain is a common cause of disability. An analysis in the Journal of Orthopaedic Research examined which non-opioid drugs are best for treating this condition.

22 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Preconception diabetes and prediabetes associated with increased risk of preterm birth

A new study examined the associations between preconception diabetes, prediabetes, and hemoglobin A1c (HbA1c) levels on the risk of preterm birth.

22 Feb 2023

LMU physician uncovers mechanisms behind immune system immaturity in prematurely born infants

LMU physician Markus Sperandio has discovered why the immune system of prematurely born babies is not working properly after birth.

22 Feb 2023

How are adverse childhood events and less than ideal cardiovascular health in adulthood associated?

Researchers evaluated associations between adverse childhood events (ACEs) and cardiovascular health (CVH).

22 Feb 2023

How does prenatal exposure to phthalates, organophosphate esters, and organophosphorus pesticides influence children’s language ability?

Researchers examined the effects of prenatal exposure to chemicals on early child language ability.

22 Feb 2023

Medical News

Satisfying relationships in mid-life associated with lower risk of multimorbidity in older age

First phase I trial of intravenous mistletoe extract to treat advanced cancer

Scientists identify mechanisms underlying autoimmunity in Down syndrome

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

Study links obesity with 21 Alzheimer's disease-related genes

Monitoring the presence of bovine meat and milk factor protein expression may help identify people at risk of colorectal cancer

Association between sleep disorders and sleep-wake disturbance with MACE or all-cause mortality in the post-stroke population

Mount Sinai study sheds new light on the role of DNA methylation in Alzheimer's disease

Analysis examines which non-opioid drugs are best for treating acute low back pain

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Preconception diabetes and prediabetes associated with increased risk of preterm birth

LMU physician uncovers mechanisms behind immune system immaturity in prematurely born infants

How are adverse childhood events and less than ideal cardiovascular health in adulthood associated?

How does prenatal exposure to phthalates, organophosphate esters, and organophosphorus pesticides influence children’s language ability?

Researchers explore Mediterranean diet and its health benefits in managing obesity

A bitter battle over the ‘orphan drug’ program leaves patients’ pocketbooks at risk

California says it can no longer afford aid for covid testing, vaccinations for migrants

In Tennessee, a Medicaid mix-up might land you on a ‘most wanted’ list

Women who have quality relationships less likely to develop multiple chronic conditions in older age

Home healthcare clinics provide better end-of-life care than general hospitals, study shows

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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