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Metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 Delta, Alpha, and Omicron variants

Researchers examined how SARS-CoV-2 variants of concern differentially use an additional metalloproteinase-dependent entry pathway to enter the host cells.

24 Feb 2022

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Researchers developed a hybrid assay incorporating immunological antibody-based viral spike protein capture with molecular nucleic acid amplification by qRT-PCR.

24 Feb 2022

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Researchers demonstrated that the SARS-CoV-2 viroporins precipitate cytokine storm via the alteration of mitochondrial physiology in severe COVID-19.

24 Feb 2022

Antibody levels against SARS-CoV-2 spike protein up to 12 months after COVID-19 infection in non-vaccinated individuals

A recent study assessed the persistence of SARS-CoV-2 antibody five and 12 months post-infection in non-vaccinated patients.

24 Feb 2022

Why pregnant people were left behind while vaccines moved at ‘warp speed’ to help the masses

Kia Slade was seven months pregnant, unvaccinated, and fighting for breath, her oxygen levels plummeting, when her son came into the world last May.

24 Feb 2022

Watch: Seniors share how they’ve made it through the pandemic

Too often the voices of older people are not heard. Judith Graham, KHN’s Navigating Aging columnist, invited nine seniors from across the country to talk candidly about their highs and lows as they enter Year 3 of the pandemic, with lives reordered by risk and restriction.

24 Feb 2022

Covid aid to protect Montana prisons and jails sits unused

Last summer, Montana created a list of more than a dozen upgrades for its state prison facilities to protect inmates and staffers from covid-19 infections, all of which would be paid for with nearly $2.5 million in federal covid relief money.

24 Feb 2022

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Researchers investigated the probability of Omicron BA.2 reinfections following SARS-CoV-2 Omicron BA.1 initial infection by whole genomic sequencing in the period of dominance of these subvariants in Denmark.

24 Feb 2022

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Researchers used a systems immunology approach to analyze the immune states of healthy and non-obese subjects who recovered from mild COVID-19 and compared them with age- and sex-matched COVID-19-naive controls.

24 Feb 2022

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Pulmonary dysfunction in pediatric patients after acute COVID-19 infection

A recent study examined the pulmonary dysfunction persistent in pediatric populations post-acute COVID-19 infection.

24 Feb 2022

Immunological landscape of England during Omicron-driven SARS-CoV-2 wave

In a new study, researchers determined the immunological landscape of England throughout the SARS-CoV-2 Omicron wave.

24 Feb 2022

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

Study examines the effect of sevoflurane on sleep disturbance caused by systemic inflammation

Getting a good night's sleep can sometimes be a challenge, but inflammation may make it even more difficult.

24 Feb 2022

Immune responses in patients with varying degrees of SARS-CoV-2 infection

In a recent research article published in the journal PLoS ONE, researchers looked at immunological responses in relation to established risk factors for serious illness. This prospective cohort study reports on long-lasting SARS-CoV-2 specific antibody and T-cellular immune responses six months after infection in rt-PCR confirmed cases of different illness severity (community and hospitalized patients).

24 Feb 2022

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

A new study posted to the bioRxiv* preprint server reports on the development of anti-RBD immunoglobulin Y (IgY) antibodies from chicken eggs to block the binding of the viral RBD to human ACE2 receptors. This approach has several advantages since chicken egg-derived IgY can be edible and polyclonal can target multiple epitopes, enhancing neutralizing activity.

23 Feb 2022

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

Every time you chew, talk, yawn, or sense the zap of a toothache, cranial nerve cells are shuttling electrochemical signals to your brain.

23 Feb 2022

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is hurting our loved ones — even those that walk on four legs. Researchers from the University of Pennsylvania documented the recovery of an 11-year old indoor housecat living in Delaware who first presented to the veterinary hospital after experiencing distressing gastrointestinal symptoms.

23 Feb 2022

Abdominal obesity may lead to greater risk of COPD and asthma in women

Obesity has been linked to a wide array of health problems. A new study suggests that abdominal obesity as measured by body mass index (BMI) and waist circumference, may result in a greater risk of chronic obstructive pulmonary disease (COPD) and asthma.

23 Feb 2022

New studies explore the potential role of bariatric surgery in reducing breast cancer risk

New studies aim to clarify the relationship between obesity and breast cancer, and explore the potential role of bariatric surgery in reducing this risk, according to a review published online in Obesity, The Obesity Society's flagship journal.

23 Feb 2022

Medical News

Metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 Delta, Alpha, and Omicron variants

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Antibody levels against SARS-CoV-2 spike protein up to 12 months after COVID-19 infection in non-vaccinated individuals

Why pregnant people were left behind while vaccines moved at ‘warp speed’ to help the masses

Watch: Seniors share how they’ve made it through the pandemic

Covid aid to protect Montana prisons and jails sits unused

Omicron BA. 2 reinfections can occur shortly following BA.1 infection

Study reveals sex-dimorphic immune imprints and in vivo functional impacts of mild COVID-19

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Pulmonary dysfunction in pediatric patients after acute COVID-19 infection

Immunological landscape of England during Omicron-driven SARS-CoV-2 wave

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

Study examines the effect of sevoflurane on sleep disturbance caused by systemic inflammation

Immune responses in patients with varying degrees of SARS-CoV-2 infection

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

Scientists discover how a rare genetic disorder disrupts key neural interactions in the developing brain

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Abdominal obesity may lead to greater risk of COPD and asthma in women

New studies explore the potential role of bariatric surgery in reducing breast cancer risk

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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