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New ESC/EACTS guidelines for the management of valvular heart disease published

The European Society of Cardiology (ESC) and European Association for Cardio-Thoracic Surgery Guidelines for the management of valvular heart disease are published online today in European Heart Journal.

28 Aug 2021

Moderate-vigorous physical activity found to be the most efficient at improving fitness

In the largest study performed to date to understand the relationship between habitual physical activity and physical fitness, researchers from Boston University School of Medicine (BUSM) have found that higher amount of time spent performing exercise (moderate-vigorous physical activity) and low-moderate level activity (steps) and less time spent sedentary, translated to greater physical fitness.

28 Aug 2021

Young children picked up extra weight during the COVID-19 pandemic

A Kaiser Permanente study of nearly 200,000 children showed that children gained excess weight during the COVID-19 pandemic, especially those between 5 and 11 years old. The study was published in the Journal of the American Medical Association.

28 Aug 2021

Cognitive function of older adults could be improved through multidomain lifestyle interventions

Aging-US published "Facility-based and home-based multidomain interventions including cognitive training, exercise, diet, vascular risk management, and motivation for older adults: a randomized controlled feasibility trial" which reported that in an outcome assessor-blinded, randomized controlled trial, participants without dementia and with one or more modifiable dementia risk factors, aged 60-79 years, were randomly assigned to the facility-based MI, the home-based MI, or the control group receiving general health advice.

28 Aug 2021

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Oncotarget published "Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis" which reported that microscopic imaging, immunocytochemistry, wound healing assay, caspase-cleaved cytokeratin 18 CytoDeath ELISA assay, immunofluorescence labeling assays for apoptosis, hypoxia, Western Blotting, Tunnel assay, measurement of 5-HT secretion by carbon fiber amperometry assay, quantitative methylation-specific PCR, morphologic changes, cell viability, apoptosis activity and the expression levels of phospho-Akt1, Akt1, HIF-1α, PI3K, p21, CAIX, 5-HT, phospho-mTOR, and mTOR in xenografts derived from typical H727 and atypical H720 BC cell lines.

28 Aug 2021

More than one-third of physician assistants suffer from burnout, study reports

More than one-third of physician assistants meet criteria for burnout, suggests a study in the September issue of JAAPA, Journal of the American Academy of PAs. The journal is published in the Lippincott portfolio by Wolters Kluwer.

28 Aug 2021

UT Southwestern orthopedic specialist performs first AR shoulder replacement surgery in Texas

The preoperative shoulder CT scan is entered into special software, which then generates a 3D model of the patient's anatomy. Physicians use the model to examine the patient's anatomy, plan incision points, mark the points for the anchor pins, and adjust the prosthetic device.

28 Aug 2021

Exercise reduces the amount of calories burned at rest in obese people, study finds

Exercise reduces the amount of calories burned at rest in people with obesity, according to a new study by researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences and the University of Roehampton.

28 Aug 2021

Study may pave way for new treatment strategies to limit the progression of solid tumors

Researchers at the University of British Columbia's faculty of medicine and BC Cancer Research Institute have uncovered a weakness in a key enzyme that solid tumour cancer cells rely on to adapt and survive when oxygen levels are low.

28 Aug 2021

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations.

28 Aug 2021

Neurons in visual cortex of the brain change their responses over time, research reveals

New research from Washington University in St. Louis reveals that neurons in the visual cortex - the part of the brain that processes visual stimuli - change their responses to the same stimulus over time.

28 Aug 2021

Pfizer COVID-19 jab side effects likely to be mild to moderate in extremely vulnerable 12-15 year olds

The side effects of the Pfizer-BioNTech jab against COVID-19 are likely to be mild to moderate and clear up quickly in 12-15 year olds at high risk of complications from the infection because of certain coexisting conditions, reveals a small study accepted for publication in the Archives of Disease in Childhood.

28 Aug 2021

Researchers measure the number of pathogens in backyard and commercial composts

Compost - organic material that is added to soil to help plants grow - is widely used by gardeners because it improves soil health and reduces the amount of organic waste in landfills. Although several studies have looked at commercial composts, very few have investigated backyard compost samples. In a new study, researchers have measured the number of pathogens in both types of compost.

28 Aug 2021

Researchers test remotely operated implantable drug delivery devices on the ISS

From Novartis to Lamborghini, Alessandro Grattoni and the Houston Methodist Research Institute have partnered with big names to leverage the International Space Station U.S. National Laboratory for space-based research and technology development with important benefits back on Earth.

28 Aug 2021

Scientists analyze the impact of two strategies in stopping COVID-19 pandemic

How can we best organise on-site workplace and school attendance periods and remote work to slow the circulation of Sars-CoV-2? Is it better to separate classes? Bring your whole team in at the same time? Set this up on daily or weekly schedules?

28 Aug 2021

Airflow optimization reduces time required to remove particulate matter from the classroom

According to the WHO, about 7 million people die each year due to air pollution. Particulate matter (PM) triggers inflammatory responses in the human body, causing asthma and other respiratory and cardiovascular diseases. It is more fatal for young and growing students. The Korea Institute of Civil Engineering and Building Technology (KICT) has reduced time required to remove particulate matter from the classroom by more than 30% by optimizing the locations of supply and return diffusers for air supplied into the classroom.

28 Aug 2021

Study discourages use of non-standard therapies for infantile spasms

Children with infantile spasms, a rare form of epileptic seizures, should be treated with one of three recommended therapies and the use of non-standard therapies should be strongly discouraged, according to a study of their effectiveness by a Weill Cornell Medicine and NewYork-Presbyterian investigator and collaborating colleagues in the Pediatric Epilepsy Research Consortium. Early treatment with an effective therapy is important for improving neurodevelopmental outcomes and, for some children, can result in permanent remission of epilepsy.

28 Aug 2021

Medical News

New ESC/EACTS guidelines for the management of valvular heart disease published

Moderate-vigorous physical activity found to be the most efficient at improving fitness

Young children picked up extra weight during the COVID-19 pandemic

Cognitive function of older adults could be improved through multidomain lifestyle interventions

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

More than one-third of physician assistants suffer from burnout, study reports

UT Southwestern orthopedic specialist performs first AR shoulder replacement surgery in Texas

Exercise reduces the amount of calories burned at rest in obese people, study finds

Study may pave way for new treatment strategies to limit the progression of solid tumors

Study opens up a new approach to incorporating MRI into multisite pancreatic clinical trials

Neurons in visual cortex of the brain change their responses over time, research reveals

Pfizer COVID-19 jab side effects likely to be mild to moderate in extremely vulnerable 12-15 year olds

Researchers measure the number of pathogens in backyard and commercial composts

Researchers test remotely operated implantable drug delivery devices on the ISS

Scientists analyze the impact of two strategies in stopping COVID-19 pandemic

Airflow optimization reduces time required to remove particulate matter from the classroom

Study discourages use of non-standard therapies for infantile spasms

Mobile telemedicine unit found to be effective in treating opioid use disorder in rural areas

Exoskeleton-assisted rehabilitation can help treat stroke survivors

NYU Tandon describes novel peptide with broad therapeutic potential to combat multiple diseases

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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