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Study identifies how SARS-CoV-2 enters and infects the brain

A recent preclinical study led by Anja Kipar of the University of Zurich and the University of Liverpool found evidence of the virus infecting and eventually provoking cell death in microglia and immune cells — but not neurons. The viral-induced apoptosis in these brain cells may explain why some long-haulers experience ‘brain fog’ months after recovery.

21 Apr 2021

Widely available HIV testing and treatment services increase life expectancy

Life expectancy among adults living with HIV receiving antiretroviral therapy (ART) in Latin America and the Caribbean has increased significantly since HIV testing and treatment services became more widely available, according to research published today in The Lancet HIV journal.

21 Apr 2021

Inhibition of Meprin Β enzyme can trigger the development of Alzheimer's disease, cancer

Researchers at Johannes Gutenberg University Mainz (JGU) in Germany and the Institute of Molecular Biology of Barcelona in Spain have discovered how the blood plasma protein fetuin-B binds to the enzyme meprin β and used a computer model to visualize their findings.

21 Apr 2021

Fast oscillations in electroencephalography can pinpoint brain tissues responsible for epileptic seizures

Professor Bin He's team at Carnegie Mellon University, in collaboration with the Mayo Clinic, has discovered that fast oscillations in scalp-recorded electroencephalography can pinpoint brain tissues responsible for epileptic seizures.

21 Apr 2021

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Like a stern bodyguard for the central nervous sytem, the blood-brain barrier keeps out anything that could lead to disease and dangerous inflammation--at least when all is functioning normally.

21 Apr 2021

Struggles caused by COVID-19 pandemic can guide towards more equitable, sustainable society

Researchers at the University of Jyväskylä highlight how the struggles caused by the COVID-19 pandemic can guide us towards an equitable use of our shared environment and a transition towards sustainability.

21 Apr 2021

Researchers study ways to improve pediatric heart transplant outcomes

Scientific research teams in California and Texas have been awarded nearly $1.4 million in grants to study ways to improve pediatric heart transplant outcomes.

21 Apr 2021

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Severe COVID-19 causes sepsis-like manifestations, intense lung injury, and multi-organ failure, all associated with the overproduction of pro-inflammatory cytokines. This "cytokine storm" directly correlates with poor prognosis in this subgroup of patients.

21 Apr 2021

Seroprevalence studies monitoring SARS-CoV-2 among vaccinees require more than spike assays

Researchers in the United States have shown that an antibody test measuring host reactivity to the nucleocapsid protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may better detect natural infection among vaccinated individuals than an assay that measures reactivity to the viral spike protein.

21 Apr 2021

Children develop strong, long-lasting immunity following SARS-CoV-2 infection

Researchers in the UK have conducted a study that may explain why children who become infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) do not generally develop severe coronavirus disease 2019 (COVID-19).

20 Apr 2021

NIH funds large Phase 3 clinical trial to test repurposed drugs for treating COVID-19 symptoms

Using an ACTIV master protocol, the trial will focus on potential interventions for mild-to-moderate illness.

20 Apr 2021

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain - an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests.

20 Apr 2021

Study explores how lessons from past crises could improve the pandemic response

The lack of accountability, poor communication and insufficient planning plaguing the government’s response to the COVID-19 pandemic -- especially in its early months -- have roots in how the nation responded to 9/11, Hurricane Katrina and the H1N1 swine flu, a new study involving the University of Washington found.

20 Apr 2021

Two extremes of female sexual behavior may be controlled by the same brain region

In many species, including humans and mice, the fluctuating levels of the hormones progesterone and estrogen determine whether the female is fertile or not. And in the case of mice, whether she's sexually receptive or not.

20 Apr 2021

FDA takes steps to add molecular tests using pooled nasal specimens in serial testing program

Today, the U.S. Food and Drug Administration took steps to further facilitate the authorization of molecular tests for screening asymptomatic individuals using pooled anterior nasal respiratory specimens in serial testing programs.

20 Apr 2021

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Just as e-cigarette ingredients can vary from one region to another, the health effects of vaping can have regional characteristics as well. A new study out of West Virginia University suggests that rural e-cigarette users are older--and often get sicker--than their urban counterparts.

20 Apr 2021

Medical News

Study identifies how SARS-CoV-2 enters and infects the brain

Widely available HIV testing and treatment services increase life expectancy

Inhibition of Meprin Β enzyme can trigger the development of Alzheimer's disease, cancer

Fast oscillations in electroencephalography can pinpoint brain tissues responsible for epileptic seizures

Blood-brain barrier and its effect on the immune system play a role in schizophrenia

Struggles caused by COVID-19 pandemic can guide towards more equitable, sustainable society

Researchers study ways to improve pediatric heart transplant outcomes

SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors

Seroprevalence studies monitoring SARS-CoV-2 among vaccinees require more than spike assays

Children develop strong, long-lasting immunity following SARS-CoV-2 infection

NIH funds large Phase 3 clinical trial to test repurposed drugs for treating COVID-19 symptoms

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Study explores how lessons from past crises could improve the pandemic response

Two extremes of female sexual behavior may be controlled by the same brain region

FDA takes steps to add molecular tests using pooled nasal specimens in serial testing program

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Researchers reveal a potential therapeutic strategy against T-cell acute lymphoblastic leukemia

Racial and ethnic diversity in schools influence student mental health, study finds

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

All-in-one test provides a promising solution for COVID-19 detection and mutational surveillance

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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