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Exercise training may slow breast cancer growth by increasing anti-tumor immune response

Exercise training may slow tumor growth and improve outcomes for females with breast cancer - especially those treated with immunotherapy drugs - by stimulating naturally occurring immune mechanisms, researchers at Massachusetts General Hospital and Harvard Medical School have found.

12 Apr 2021

Study identifies a 'window of impairment' caused by cannabis intoxication

A comprehensive analysis of 80 scientific studies has identified a 'window of impairment' of between three and 10 hours caused by moderate to high doses of the intoxicating component of cannabis, tetrahydrocannabinol (THC).

12 Apr 2021

Yale researchers provide new insights into acquired resistance to cancer immunotherapy

New research by Yale Cancer Center shows insights into modeling resistance to immune checkpoint inhibitors, a form of cancer immunotherapy.

12 Apr 2021

Early cardiac events pose major and different risks in close relatives, finds study

Family history of early cardiac events in first degree relatives such as a parent or sibling is a major risk factor, especially for premature events. Currently, data on risks in close relatives of patients with a family history of premature heart attacks, chronic stable angina or peripheral vascular disease are sparse.

12 Apr 2021

Adult survivors of AYA cancers more likely to experience higher medical financial hardship

New study finds higher medical financial hardship in adult survivors of adolescent and young adult (AYA) cancers than in adults without a history of cancer in the United States.

12 Apr 2021

Researchers receive $500,000 grant to test novel approach for restoring damaged muscles after injury

Researchers from the University of Tennessee Health Science Center have received a $500,000 grant over three years from the Department of Defense to test a novel strategy using mitochondria transplantation therapy for restoration of neuromuscular structure and function after injury.

12 Apr 2021

New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients

A new test that measures the quantity and quality of inactive HIV viruses in the genes of people living with HIV may eventually give researchers a better idea of what drugs work best at curing the disease.

12 Apr 2021

Novel immunotherapy approach may offer therapeutic advantages for melanoma

In a new study led by Yale Cancer Center, researchers have advanced a tumor-targeting and cell penetrating antibody that can deliver payloads to stimulate an immune response to help treat melanoma.

12 Apr 2021

Early cannabis use may increase risk of developing heart disease

Smoking cannabis when you're young may increase your risk of developing heart disease later, according to a recent University of Guelph study.

12 Apr 2021

Study demonstrates profound anhedonia in people with frontotemporal dementia

People with early-onset dementia are often mistaken for having depression and now Australian research has discovered the cause: a profound loss of ability to experience pleasure - for example a delicious meal or beautiful sunset - related to degeneration of 'hedonic hotspots' in the brain where pleasure mechanisms are concentrated.

12 Apr 2021

Breast cancer survivors with excess body weight at increased risk of developing second cancer

Breast cancer survivors who are overweight have a statistically significant increased risk of developing second primary cancers, according to results from a study conducted by Kaiser Permanente researchers and published in the Journal of the National Cancer Institute.

12 Apr 2021

Researchers reveal the positive effects of exercise on the liver

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide, affecting as much as a quarter of humanity. It is characterized by fat accumulation in liver cells and may progress to inflammation, cirrhosis and liver failure.

12 Apr 2021

UHN performed first double-lung transplant after COVID-19 in Canada

University Health Network has performed what is believed to be the first lung transplant in Canada on a patient whose lungs were irreparably damaged by COVID-19.

12 Apr 2021

Broadly cross-reactive antibody to SARS-CoV-2 RBD with robust resistance to mutational escape

A new study addresses an urgent need – namely, a therapeutic antibody directed specifically against a key SARS-CoV-2 antigen which is highly conserved among similar viruses, and is not easily bypassed by viral escape mutations.

12 Apr 2021

Small molecule inhibitors of SARS-CoV-2 identified by screening

A new study describes the identification of small molecule inhibitors that block the catalytic activity of the crucial viral non-structural protein 5 (nsp5), using a large-scale screening method.

12 Apr 2021

P681 mutation has little impact on transmissibility in the SARS-CoV-2 UK variant, finds study

A new preprint, recently released on the bioRxiv* server, explores the impact of a single mutation, the P681H mutation, on the transmissibility of the virus.

12 Apr 2021

Current hygiene guidelines appropriate for UK and SA variants of SARS-CoV-2, study finds

Many different variants and lineages have arisen from the ancestral Wuhan-Hu1 strain of the SARS-CoV-2. This requires careful attention to control measures since many are more infective and transmissible than the older strains. A recent study compares the UK variant of this virus with the wildtype in terms of susceptibility to routine cleaning and disinfection measures.

12 Apr 2021

Researchers provide ultrastructural details of SARS-CoV-2-infected respiratory epithelial cells

A team of scientists from the United Kingdom recently investigated the ultrastructural details of the attachment, entry, and budding processes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the human airway epithelium. They have used a highly differentiated air-liquid interface cultures of airway epithelium to thoroughly investigate the viral infection cycle. The study is currently available on the bioRxiv* preprint server.

12 Apr 2021

Researchers explore an inhalable SARS-CoV-2 nanobody therapy

Even as vaccines against SARS-CoV-2 are being developed and administered at an unprecedented pace, treating this infection remains a challenge. To address this, researchers from China have used nanobodies (Nb) as a possible therapeutic approach. They reported Nb phage display libraries derived from four camels immunized with the SARS-CoV-2 spike RBD.

12 Apr 2021

Biden seeks $400 billion to buttress long-term care. A look at what’s at stake.

There's widespread agreement that it's important to help older adults and people with disabilities remain independent as long as possible. But are we prepared to do what's necessary, as a nation, to make this possible?

12 Apr 2021

Medical News

Exercise training may slow breast cancer growth by increasing anti-tumor immune response

Study identifies a 'window of impairment' caused by cannabis intoxication

Yale researchers provide new insights into acquired resistance to cancer immunotherapy

Early cardiac events pose major and different risks in close relatives, finds study

Adult survivors of AYA cancers more likely to experience higher medical financial hardship

Researchers receive $500,000 grant to test novel approach for restoring damaged muscles after injury

New test offers a simpler way to quantify the reservoir of intact viruses in HIV patients

Novel immunotherapy approach may offer therapeutic advantages for melanoma

Early cannabis use may increase risk of developing heart disease

Study demonstrates profound anhedonia in people with frontotemporal dementia

Breast cancer survivors with excess body weight at increased risk of developing second cancer

Researchers reveal the positive effects of exercise on the liver

UHN performed first double-lung transplant after COVID-19 in Canada

Broadly cross-reactive antibody to SARS-CoV-2 RBD with robust resistance to mutational escape

Small molecule inhibitors of SARS-CoV-2 identified by screening

P681 mutation has little impact on transmissibility in the SARS-CoV-2 UK variant, finds study

Current hygiene guidelines appropriate for UK and SA variants of SARS-CoV-2, study finds

Researchers provide ultrastructural details of SARS-CoV-2-infected respiratory epithelial cells

Researchers explore an inhalable SARS-CoV-2 nanobody therapy

Biden seeks $400 billion to buttress long-term care. A look at what’s at stake.

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

The importance of ketones from a clinical and medical perspective

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