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Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

In order to fight pathogens, mast cells regulate inflammatory reactions of the immune system. Both mast cells and neutrophils are white blood cells and are critical for the body's immune defense.

5 Feb 2021

Neuromuscular training in cardiac rehabilitation improves quality of life in heart attack patients

Neuromuscular training improves balance, stability, coordination and reaction speed, increasing patients’ ability to perform daily chores and allowing them to gain quality of life.

5 Feb 2021

Men’s understanding of fertility awareness has been largely understudied, shows study

'I think children are cute', 'the future of our world looks bleak' — why men choose to have or not to have children has been investigated by a Malmö University researcher.

5 Feb 2021

Better design of deep learning studies can lead to faster transformation of medical practices

A new Perspective article in Nature Reviews Cancer discusses reasons for the moderate progress and describes remedies designed to facilitate the transition to the clinic.

5 Feb 2021

Researchers to create computational models to improve treatments for ovarian cancer

The 5-year research project involves 14 organizations in seven EU countries and is funded by €15 M from the EU.

4 Feb 2021

Research shows intestinal parasite infestations reduce COVID-19 severity

Now, new research out of Mekelle, Ethiopia, examines the role of parasitic infestation on the prognosis of COVID-19. The research paper, which appears on the preprint server medRxiv, shows that intestinal parasitosis is protective against severe COVID-19.

4 Feb 2021

Greater muscle strength associated with lower risk of COVID-19 hospitalization

A new preprint research paper posted to the medRxiv* server discusses the results of a study exploring the relationship between increased muscle strength and hospitalization for severe COVID-19.

4 Feb 2021

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

A new preprint research paper posted to the bioRxiv server reports the development of highly effective neutralizing nanobodies targeting the viral receptor-binding domain (RBD), thus disrupting its engagement with the host cell angiotensin-converting enzyme 2 (ACE2) receptor.

4 Feb 2021

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

A new preprint posted to the bioRxiv server demonstrates that similar mucins and mucin-like proteins cannot only suppress HIV-1 infectivity via blockage of viral attachment to the host cells but can block infection by multiple enveloped viruses.

4 Feb 2021

SARS-CoV-2 N501Y mutation adversely affects cellular immune response

Among these is the B.1.1.7 SARS-CoV-2 variant, with its characteristic N501Y mutation. A new preprint on the bioRxiv server reports the impact of this mutation on CD4 T cell responses, including antigen presentation on cells expressing Major Histocompatibility Complex (MHC) class II molecules.

4 Feb 2021

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

Scripps Research, a globally recognized nonprofit biomedical research institute, today announced a collaborative research program with Tempus, a leader in precision medicine and artificial intelligence, to develop a predictive model of glucose responses in people with and without type 2 diabetes.

4 Feb 2021

Pharmacologist lays out a plan to improve the equity of drug development

In a new perspective piece published in the Feb. 5 issue of Science, pharmacologist Namandje Bumpus, Ph.D. -- who recently became the first African American woman to head a Johns Hopkins University School of Medicine department, and is the only African American woman leading a pharmacology department in the country -- outlines the molecular origins for differences in how well certain drugs work among distinct populations.

4 Feb 2021

Study: Only 14% of the Bernese population developed antibodies against SARS-CoV-2

In the canton of Bern, only 14% of the adult population were infected with the coronavirus and developed antibodies against SARS-CoV-2.

4 Feb 2021

Study shows psychological impact of perceived COVID-19 health threat among Black Americans

As the coronavirus pandemic continues to devastate communities worldwide, Black Americans who face racial discrimination in hospitals and doctor's offices weather additional stresses that can exacerbate threats from COVID-19.

4 Feb 2021

COVID-19 vaccination alone may not end the pandemic

A simulation-based study conducted at the Miami University, USA, has revealed that vaccination of the general population against coronavirus disease 2019 (COVID-19) alone is not sufficient to control the pandemic, given the current availability and implementation strategies.

4 Feb 2021

Dialysis patients are 4 times more likely to die from COVID-19

People undergoing long-term dialysis are almost 4 times more likely to die from COVID-19 and should be prioritized for vaccination, found a new Ontario study published in CMAJ.

4 Feb 2021

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

A team of scientists from India has recently tested the efficacy and immunogenicity of two different concentrations of a plasmid DNA-based vaccine candidate ZyCoV-D. The findings reveal that the vaccine candidate administered via Needle Free Injection System (NFIS) can significantly induce the production of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific IgG and neutralizing antibodies for a prolonged period.

4 Feb 2021

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

Inflammation in the blood could serve as a new biomarker to help identify patients with advanced pancreatic cancer who won't respond to the immune-stimulating drugs known as CD40 agonists, suggests a new study from researchers in the Abramson Cancer Center of the University of Pennsylvania published in JCI Insight.

4 Feb 2021

Research shows how air pollution has a detrimental impact on cardiovascular health

Tiny particles of air pollution -- called fine particulate matter -- can have a range of effects on health, and exposure to high levels is a known risk factor for cardiovascular disease.

4 Feb 2021

New project to improve air filtering in ambulances

Cranfield University is working with Q-Flo, Cambridge University and NHS England to record experimental airflow data from a modern NHS ambulance under different driving conditions.

4 Feb 2021

Medical News

Study may lead to new therapeutic strategies to reduce allergic responses, inflammatory reactions

Neuromuscular training in cardiac rehabilitation improves quality of life in heart attack patients

Men’s understanding of fertility awareness has been largely understudied, shows study

Better design of deep learning studies can lead to faster transformation of medical practices

Researchers to create computational models to improve treatments for ovarian cancer

Research shows intestinal parasite infestations reduce COVID-19 severity

Greater muscle strength associated with lower risk of COVID-19 hospitalization

Alpaca nanobodies neutralize SARS-CoV-2 in vitro

SHREK proteins mediate broad spectrum antiviral host immunity, including against SARS-CoV-2

SARS-CoV-2 N501Y mutation adversely affects cellular immune response

Scripps Research collaborates with Tempus to develop a predictive model of glucose responses

Pharmacologist lays out a plan to improve the equity of drug development

Study: Only 14% of the Bernese population developed antibodies against SARS-CoV-2

Study shows psychological impact of perceived COVID-19 health threat among Black Americans

COVID-19 vaccination alone may not end the pandemic

Dialysis patients are 4 times more likely to die from COVID-19

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

Novel biomarker may help identify which pancreatic cancer patients respond to CD40 agonists

Research shows how air pollution has a detrimental impact on cardiovascular health

New project to improve air filtering in ambulances

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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