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One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

In a new study, published on the pre-print server medRxiv, an international team of researchers found that a one-dose policy may increase the potential for antigenic evolution. The study revealed that focusing on one dose may decrease infections in the short term, but longer-term outcomes rely on this immune strength.

8 Feb 2021

HIV: New therapeutic approach to restore the effectiveness of immune cells

Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique has identified a therapeutic approach to restore the effectiveness of immune cells.

8 Feb 2021

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers.

8 Feb 2021

Study: Older adults classified as "prediabetic" seldom progress to full diabetes

Older adults who are classified as having "prediabetes" due to moderately elevated measures of blood sugar usually don't go on to develop full-blown diabetes, according to a study led by researchers at Johns Hopkins Bloomberg School of Public Health.

8 Feb 2021

New study to examine the effects of MS disease-modifying therapy on cognitive fatigue

Kessler Foundation researchers have received support from Genentech, a member of the Roche Group, to conduct an investigator-initiated study on the effects of ocrelizumab (Ocrevus) on cognitive fatigue in individuals with relapsing-remitting multiple sclerosis (MS).

8 Feb 2021

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

In a recent medRxiv preprint publication, the team led by Professor Ravindra K. Gupta has assessed the real-world immune responses following the vaccination against the SARS-CoV-2. The team measured 1) IFN-gamma (interferon-gamma) T cell responses, 2) both total IgG Spike/ IgG Spike RBD (receptor binding domain) and 3) neutralizing antibody responses to Spike in sera.

8 Feb 2021

Take-at-home tests increase colorectal cancer screening rates by more than 1,000%

Colorectal cancer screening rates jumped by more than 1,000 percent when researchers sent take-at-home tests to patients overdue for testing at a community health center that predominantly serves people of color.

8 Feb 2021

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

An analysis of Kaiser Permanente members in Northern California early in the COVID-19 pandemic found racial and ethnic disparities in the likelihood of testing positive for the coronavirus, but no significant disparities in mortality among those who were hospitalized.

8 Feb 2021

Study examines people's behavioral responses to face mask mandates during the pandemic

Face masks mandates have led people to spend less time at home, but whether this has exposed Americans to more risk is still a question, according to a new study published Thursday in Scientific Reports.

8 Feb 2021

History of vaccines offers guidance on COVID-19 prevention in pregnant women

Pregnant women, who are at increased risk of preterm birth or pregnancy loss if they develop a severe case of COVID-19, need the best possible guidance on whether they should receive a COVID-19 vaccine, according to an article by two UT Southwestern obstetricians published today in JAMA.

8 Feb 2021

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

A new nanoparticle-based drug can boost the body's innate immune system and make it more effective at fighting off tumors, researchers at UT Southwestern have shown.

8 Feb 2021

Brain protein responsible for causing Alzheimer's disease also plays a protective role

Findings from a new study on Alzheimer's disease (AD), led by researchers at the University of Saskatchewan, could eventually help clinicians identify people at highest risk for developing the irreversible, progressive brain disorder and pave the way for treatments that slow or prevent its onset.

8 Feb 2021

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Researchers in the United States have identified specific immune correlates that might be key to ensuring that vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protects against not only disease, but also viral transmission and emerging variants.

8 Feb 2021

Real-time tool can rapidly predict mortality for patients facing transfer between hospitals

With the aid of sophisticated machine learning, researchers at UPMC and the University of Pittsburgh School of Medicine demonstrated that a tool they developed can rapidly predict mortality for patients facing transfer between hospitals in order to access higher-acuity care.

8 Feb 2021

Machine learning can help improve predictions of mortality risk

Researchers at Geisinger have found that a computer algorithm developed using echocardiogram videos of the heart can predict mortality within a year.

8 Feb 2021

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model

A combination of radionuclide therapy and immunotherapy has proven successful in slowing the progression of prostate cancer and increasing survival time, according to new research published in the February issue of The Journal of Nuclear Medicine.

8 Feb 2021

RIT researcher validates popular tool for measuring child feeding practices

A Rochester Institute of Technology researcher has validated a tool measuring adherence to a popular child feeding approach used by pediatricians, nutritionists, social workers and child psychologists to assess parents' feeding practices and prevent feeding problems.

8 Feb 2021

Medical News

One-dose SARS-CoV-2 vaccine policy may lead to antigenic evolution, study finds

HIV: New therapeutic approach to restore the effectiveness of immune cells

Compound isolated from Ophiura sarsii can be used as an affordable drug for photodynamic therapy

Study: Older adults classified as "prediabetic" seldom progress to full diabetes

New study to examine the effects of MS disease-modifying therapy on cognitive fatigue

Pfizer-BioNTech COVID-19 vaccine immune response in the elderly

Take-at-home tests increase colorectal cancer screening rates by more than 1,000%

Analysis finds racial and ethnic disparities in the odds of testing positive for COVID-19

Study examines people's behavioral responses to face mask mandates during the pandemic

History of vaccines offers guidance on COVID-19 prevention in pregnant women

New nanoparticle-based drug boosts the body’s innate immune system to fight tumors

Brain protein responsible for causing Alzheimer's disease also plays a protective role

4th preclinical study for Novavax in non-human primates, tests SARS-CoV-2 variants

Real-time tool can rapidly predict mortality for patients facing transfer between hospitals

Machine learning can help improve predictions of mortality risk

Study shows efficacy of radionuclide therapy–immunotherapy combination in prostate cancer model

RIT researcher validates popular tool for measuring child feeding practices

Moderna's COVID-19 vaccine effective against emerging variants

New study reveals post-traumatic growth during the COVID-19 pandemic

Study elucidates the mode of action of SGLT2 inhibitors in diabetes

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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