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Albumedix enters into collaboration agreement with Cell and Gene Therapy Catapult

Albumedix Ltd. (‘Albumedix’), an enabler of advanced therapies and the world leader in recombinant human albumin (rAlb), announced today that they have entered into a collaboration agreement with Cell and Gene Therapy Catapult (CGT Catapult) to investigate the use of Albumedix´ proprietary albumin-based solutions for advanced therapy applications, including viral vectors manufacturing.

From Albumedix Ltd. 2 Feb 2021

Simvastatin is a promising drug candidate for treatment of ovarian clear cell carcinomas

Oncotarget recently published "Simvastatin is a potential candidate drug in ovarian clear cell carcinomas" which reported that based on previous studies, the authors assessed the anti-proliferative effect of simvastatin, a Rho GTPase interfering drug, in three OCCC cell lines: JHOC-5, OVMANA and TOV-21G, and one high-grade serous ovarian cancer cell line, Caov3. The authors used the Rho GTPase interfering drug CID-1067700 as a control.

2 Feb 2021

50% of patients with uncontrolled asthma smoke cannabis, shows new survey

As the number of states increases where medical and recreational cannabis use is legal, so does the importance that physicians discuss with patients the effects of cannabis on those with asthma.

2 Feb 2021

ZyCoV-D DNA vaccine immunogenic against SARS-CoV-2 in animal models

In the absence of effective therapeutics or preventives, vaccines have become the focus of attention. Though over 170 vaccines are in preclinical and about 60 in clinical development, very few are based on plasmid DNA technology. However, a new preprint research paper posted to the bioRxiv* server reports the immunogenicity of a DNA vaccine candidate.

2 Feb 2021

Why SARS-CoV-2 B.1.1.7 is more virulent

A new preprint research paper by scientists from Sweden and India attempts to provide a preliminary answer to these questions using computational modeling. The research, which appears on the bioRxiv* server, predicts increased virulence with the new variant. If validated, this could help public health authorities prepare for new variants' possible impact as they emerge.

2 Feb 2021

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2

Among the hundred million or so cases of coronavirus disease 2019 (COVID-19) that have occurred since the pandemic began, pregnant women have been a conspicuous risk group. However, the exact nature of the risk they and their fetuses face, and the mechanism by which it operates, is far from clear.

2 Feb 2021

Study: MRI is reliable for intrapelvic T staging of neuroendocrine carcinoma

Oncotarget recently published "Neuroendocrine carcinoma of uterine cervix findings shown by MRI for staging and survival analysis – Japan multicenter study" which reported that to investigate neuroendocrine carcinoma of the uterine cervix cases for MRI features and staging, as well as pathological correlations and survival.

2 Feb 2021

Application radar COVID detects twice as many contacts of people infected with SARS-Cov2

The application Radar COVID detects twice as many close contacts of people infected with the virus SARS-Cov2 as the manual tracing system. This is the conclusion of the first scientific study that was carried out to assess the application in a trial carried out last summer on the island of La Gomera in the Canary Islands.

2 Feb 2021

Synthetic biology can help create complex embryo

Richard Feynman, one of the most respected physicists of the twentieth century, said "What I cannot create, I do not understand". Not surprisingly, many physicists and mathematicians have observed fundamental biological processes with the aim of precisely identifying the minimum ingredients that could generate them. One such example are the patterns of nature observed by Alan Turing.

2 Feb 2021

Evidence that Long COVID-19 impacts children

The ongoing coronavirus 2019 (COVID-19) pandemic has caused over one hundred million reported infections, with over 2.23 million deaths worldwide. While most cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are asymptomatic or mild, some patients report long-haul symptoms, often severely debilitating in nature. However, it is unclear how many children are affected similarly.

2 Feb 2021

Researchers investigate ski resorts to assess risk of COVID-19 infection

Where do the greatest risks of infection lurk? How can you protect yourself and others even better? Scientists all over the world are working to expand knowledge about Covid-19 – including at Empa.

2 Feb 2021

Study explores merits and risks of bariatric surgery in younger teens

Obesity and its duration are significant risk factors for type 2 diabetes, cardiovascular events, multiple cancers, and decreased quality of life. According to the Centers for Disease Control and Prevention, obesity affects 20.6% of adolescents ages 12-19 in the United States, meaning a potential lifetime of dealing with this condition.

2 Feb 2021

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Evidence suggests particulate matter is the air pollutant which poses the greatest threat to global health. Studies have shown that exposure to particulate matter smaller than 2.5 microns is associated with acute and chronic elevations in blood pressure (BP) as well as hypertension.

2 Feb 2021

Research shows a promising alternative to personalized deep brain stimulation

Millions of patients suffering from neurological and mental disorders such as depression, addiction, and chronic pain are treatment-resistant. In fact, about 30% of all major depression patients do not respond at all to any medication or psychotherapy.

2 Feb 2021

Updated concussion guidelines reduced length of symptoms among athletes

The adoption of recommended changes in concussion management led to a reduction in the length of symptoms among 11- to 18-year-old athletes with first-time, sports-related concussions, according to new research in the Journal of Osteopathic Medicine.

2 Feb 2021

Students from lower socio-economic groups are less likely to participate in sports

Students from lower socio-economic groups (SEG) are less likely to participate in sport or physical activity at university, research from Sheffield Hallam University has found.

1 Feb 2021

Researchers discover novel metabolic gatekeeper mechanism for leukemia

In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia.

1 Feb 2021

2MeOE2 induces apoptosis in ovarian cancer cells, indicates study

Oncotarget published "The pro-apoptotic actions of 2-methoxyestradiol against ovarian cancer involve catalytic activation of PKCδ signaling" which reported that the authors have previously shown that a flaxseed-supplemented diet decreases both the incidence and severity of ovarian cancer in laying hens, also induces CYP1A1 expression in liver.

1 Feb 2021

SARS-CoV-2 triggers development of new-onset IgG autoantibodies in hospitalized COVID-19 patients

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent for coronavirus disease 2019 (COVID-19), is associated with several clinical features common in autoimmune diseases as myalgias, arthralgias, fatigue, and rashes. COVID-19 patients also exhibit less common autoimmunity manifestations such as myositis, thrombosis, myocarditis, encephalitis, vasculitis, and arthritis.

1 Feb 2021

Characteristics of each district impact the spread of COVID-19, shows study

Per capita income, population volume and density, the structure of cities, transport infrastructure or whether districts have their own schools are all factors that can affect the spread of COVID-19.

1 Feb 2021

Medical News

Albumedix enters into collaboration agreement with Cell and Gene Therapy Catapult

Simvastatin is a promising drug candidate for treatment of ovarian clear cell carcinomas

50% of patients with uncontrolled asthma smoke cannabis, shows new survey

ZyCoV-D DNA vaccine immunogenic against SARS-CoV-2 in animal models

Why SARS-CoV-2 B.1.1.7 is more virulent

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2

Study: MRI is reliable for intrapelvic T staging of neuroendocrine carcinoma

Application radar COVID detects twice as many contacts of people infected with SARS-Cov2

Synthetic biology can help create complex embryo

Evidence that Long COVID-19 impacts children

Researchers investigate ski resorts to assess risk of COVID-19 infection

Study explores merits and risks of bariatric surgery in younger teens

Intensive BP lowering reduces cardiovascular risk in patients exposed to air pollution

Research shows a promising alternative to personalized deep brain stimulation

Updated concussion guidelines reduced length of symptoms among athletes

Students from lower socio-economic groups are less likely to participate in sports

Researchers discover novel metabolic gatekeeper mechanism for leukemia

2MeOE2 induces apoptosis in ovarian cancer cells, indicates study

SARS-CoV-2 triggers development of new-onset IgG autoantibodies in hospitalized COVID-19 patients

Characteristics of each district impact the spread of COVID-19, shows study

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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