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Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

A new study published on the preprint server bioRxiv in September 2020 reports a novel RNA vaccine platform that shows robust protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in mice and performs much better than a conventional mRNA vaccine. This could allow single-dose immunization, allowing progress towards global vaccination.

6 Sep 2020

Seasonal influenza and COVID-19 risk

In a new study published on the preprint server medRxiv, researchers from Laval University and McGill University in Canada reviewed evidence from 18 relevant studies on a possible interaction between influenza vaccines on non-influenza respiratory disease (NIRD).

6 Sep 2020

Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Based on structural similarities with other targets of the gamma-secretase system, researchers from Columbia University Irving Medical Center in the United States show that the SARS-CoV-2 receptor for cell entry may be affected by its proteolytic activity. Their results are currently freely available in a bioRxiv preprint paper.

6 Sep 2020

Antibody responses against seasonal common cold coronaviruses may protect against SARS-CoV-2

With the use of an accurate high throughput assay, researchers from the Weizmann Institute of Science and Magen David Adom Blood Services in Israel showed substantial inter-individual variability and antibody cross-reactivity against seasonal coronaviruses upon SARS-CoV-2 infection, with important implications for immune surveys and vaccines. The study is currently available on the medRxiv* preprint server.

6 Sep 2020

Transparent Government builds trust and successful COVID-19 containment

The combined impact of the pandemic and these non-pharmaceutical interventions (NPIs) has taken a heavy toll on society, and this has led to much discussion as to the relative merits of these measures. A recent study published on the preprint server medRxiv in September 2020 shows that public trust is vital for the success of any such intervention.

6 Sep 2020

Twitter-propagated COVID-19 misinformation from credible sources has a huge impact

In March, in the early days of the coronavirus pandemic in Europe, a tweet from the French Health Minister, Olivier Verán, advised patients with COVID-19 not to take ibuprofen, an anti-inflammatory drug with analgesic and antipyretic properties.

5 Sep 2020

Monitoring the activity of unconventional T cells could predict COVID-19 severity

Researchers in France have discovered that patients suffering from severe COVID-19 show changes in a class of immune cells known as unconventional T cells.

5 Sep 2020

MIS-C linked to COVID-19 damages children's hearts

Multisystem inflammatory syndrome in children (MIS-C), believed to be linked to COVID-19, damages the heart to such an extent that some children will need lifelong monitoring and interventions, said the senior author of a medical literature review published Sept. 4 in EClinicalMedicine, a journal of The Lancet.

5 Sep 2020

Mason researchers to provide biostatistics and bioinformatic analysis for new project

Virginia Espina, Research Associate Professor, Applied Proteomics and Molecular Medicine, received $21,000 from Baylor Research Institute for a project in which Mason researchers are providing biostatistics and bioinformatic analysis for integrating multi-omic data sets from a breast cancer cohort.

5 Sep 2020

COVID-19 is not characterized by a cytokine storm, shows study

Does the COVID-19 cytokine storm exist? Inflammatory proteins, also known as cytokines, play a crucial role in the immune response. If this immune response is too strong, a phenomenon known as "cytokine storm", it can cause harm to the patient.

5 Sep 2020

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

The hemoglobin in the red blood cells ensures that our body cells receive sufficient oxygen. When the blood pigment is broken down, "heme" is produced, which in turn can influence the protein cocktail in the blood.

5 Sep 2020

Common class of drugs may be associated with increased risk of cognitive decline

A team of scientists, led by researchers at University of California San Diego School of Medicine, report that a class of drugs used for a broad array of conditions, from allergies and colds to hypertension and urinary incontinence, may be associated with an increased risk of cognitive decline, particularly in older adults at greater risk for Alzheimer's disease.

5 Sep 2020

Early identification, treatment is vital to avoid COVID-19-related health anxieties in children

Early identification and treatment is vital to avoid long-term mental health consequences from COVID-19 among children and young people, say researchers.

5 Sep 2020

IU researcher receives NCI grant to study side effects of cancer treatment

A researcher at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center has been awarded a five-year, $5.7 million National Cancer Institute grant to evaluate long-term health outcomes for cancer patients who receive platinum-based chemotherapies.

5 Sep 2020

Tailored obesity intervention program offers hope for weight loss in underserved patients

Low-income Louisiana patients enrolled in a tailored obesity intervention program lost much more weight than counterparts receiving usual care. Study results were published this week in The New England Journal of Medicine.

5 Sep 2020

Patient priorities for optimal transplant and living donor advocacy during COVID-19 and beyond

In a newly published paper, the authors first paint the vision of what optimal patient advocacy can do to overcome the challenges described by kidney transplant patients and donors and then describe how to make that vision a reality, especially during the COVID-19 pandemic.

5 Sep 2020

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days.

5 Sep 2020

New project to increase provision for trauma and emergency care in Zambia during COVID-19 pandemic

More than £170,000 will be used to boost trauma and emergency nursing in Zambia to help the country cope with the strain on services caused by the COVID-19 pandemic.

5 Sep 2020

Ending Preventable Maternal Mortality initiative aims to reduce global maternal mortality by 2030

Ending Preventable Maternal Mortality is a global initiative with the ultimate goal of ending preventable maternal mortality to support achievement of Sustainable Development Goals targets to attain an average global maternal mortality ratio of less than 70 per 100 000 live births by 2030.

5 Sep 2020

Historical case studies: Pandemics in past societies

Whether it's the plague, cholera or currently COVID-19: epidemics are part of human history. Long before there were vaccinations or microscopes for the investigation of pathogens, societies had to develop coping strategies.

5 Sep 2020

Medical News

Novel RNA vaccine from Arcturus Therapeutics protects mice against SARS-CoV-2

Seasonal influenza and COVID-19 risk

Study shows SARS-CoV-2 cell receptor is a novel target of the gamma-secretase enzyme complex

Antibody responses against seasonal common cold coronaviruses may protect against SARS-CoV-2

Transparent Government builds trust and successful COVID-19 containment

Twitter-propagated COVID-19 misinformation from credible sources has a huge impact

Monitoring the activity of unconventional T cells could predict COVID-19 severity

MIS-C linked to COVID-19 damages children's hearts

Mason researchers to provide biostatistics and bioinformatic analysis for new project

COVID-19 is not characterized by a cytokine storm, shows study

Study may provide the basis for better diagnostic, therapeutic approaches to blood diseases

Common class of drugs may be associated with increased risk of cognitive decline

Early identification, treatment is vital to avoid COVID-19-related health anxieties in children

IU researcher receives NCI grant to study side effects of cancer treatment

Tailored obesity intervention program offers hope for weight loss in underserved patients

Patient priorities for optimal transplant and living donor advocacy during COVID-19 and beyond

Early-phase Russian trials reveal safety and immunogenicity of two formulations of a two-part vaccine

New project to increase provision for trauma and emergency care in Zambia during COVID-19 pandemic

Ending Preventable Maternal Mortality initiative aims to reduce global maternal mortality by 2030

Historical case studies: Pandemics in past societies

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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