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Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Now, a team of researchers at the University of Alberta in Canada has identified viral inhibitors that they claim are potential candidates as a treatment for COVID-19. The team is set to launch clinical trials of the drug that is used as a treatment for a type of coronavirus in cats.

31 Aug 2020

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Cardiovascular disease is the leading cause of death in humans. Worldwide, as the population ages, the burden of treating heart failure is increasing; opportunities for heart transplantation cannot keep pace.

31 Aug 2020

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

A new study published on the preprint server bioRxiv* in August 2020 reports the disease-mitigating effects of a serum protein called serum amyloid P (SAP) in mice exposed to a peptide that mimics the clinical signs of severe COVID-19 in humans.

30 Aug 2020

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

In a fascinating new preprint paper published on bioRxiv* in August 2020, the researchers report “the synthesis and antiviral evaluation of three novel lipophilic prodrugs of RVn-monophosphate that are substantially more active than Remdesivir in cells infected with SARS-CoV-2.” These could be of immense use in treating COVID-19 patients early and helping to end transmission.

30 Aug 2020

Rabbits susceptible to SARS-CoV-2: Red flag for potential virus reservoir

A new study by scientists in the Netherlands and published on the preprint server bioRxiv* in August 2020 shows that the severe acute respiratory coronavirus-2 (SARS-CoV-2) can infect rabbits, which opens the door for possible circulation in rabbit farms and another potential source of animal to human SARS-CoV-2 infection. This finding calls for urgent research on the prevalence of the virus in farmed rabbits.

30 Aug 2020

Using SARS-CoV-2 epitope to construct a vaccine

A new study published on the preprint server bioRxiv* in August 2020 reports the use of prediction and advanced simulation techniques to identify a novel T cell epitope on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could serve as the basis for a customized vaccine with broad-based efficacy.

30 Aug 2020

Australia’s readiness for emergencies

Seven in 10 Aussies say strong community bonds sustain them through COVID19, but more action needed to prepare for future lockdowns and looming disasters.

30 Aug 2020

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

However, the nucleocapsid (N) protein is also extremely abundant and, therefore, a useful target for both vaccine and diagnostic test development. A new study published on the preprint server bioRxiv in August 2020 reveals the structure of this protein, a valuable step in using it for these purposes.

30 Aug 2020

Severe and fatal COVID-19 is rare in children

Now, a new study by researchers at the Universities of Edinburgh and Liverpool, Imperial College London, and the Royal Hospital for Children, Glasgow in the United Kingdom has shown that children and teenagers are less likely than adults to develop severe COVID-19 or die from the disease.

30 Aug 2020

Evidence of SARS-CoV-2 spreading in an airplane toilet

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease (COVID-19), is still actively spreading like wildfire, with nearly 300,000 new infections reported daily across the globe. Early on in the outbreak in China, scientists said that the virus could spread through respiratory droplets, when a person coughs, sneezes, or speaks.

30 Aug 2020

FDA announces public meeting to discuss development and licensure of COVID-19 vaccines

The U.S. Food and Drug Administration announced that a public meeting of the Vaccines and Related Biological Products Advisory Committee will be held on CutOct. 22, 2020, to discuss the general matter of the development, authorization, and/or licensure of vaccines indicated to prevent COVID-19.

29 Aug 2020

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Researchers from Sechenov University together with Russian and Iranian colleagues described currently known approaches to the treatment of SARS-CoV-2 infection.

29 Aug 2020

Canada announces $10 million core funding to tackle world water crisis

Canada today announced a CDN$10 million extension of core funding through 2025 for the UN University Institute for Water, Environment and Health, a research organization at the forefront of pressing global water challenges.

29 Aug 2020

Race to produce COVID vaccines should not leave the poor left behind, says expert

Race to produce vaccines against COVID-19 must ensure that the poor are not left behind, says Crispin Maslog. A mad race to produce a vaccine against COVID-19 has begun with the world's superpowers leading the pack.

29 Aug 2020

Researchers delve into marital realities facing women married to professional athletes

In a new book based on nearly 30 years of study, Oregon State University researcher Steven M. Ortiz delves into the marital realities facing women married to professional athletes, including infidelity, sexism and a significant power imbalance in their relationships.

29 Aug 2020

Medical News

Cat antiviral that inhibits SARS-CoV-2 fast-tracked for human clinical trials

Researchers identify roles of matrix stiffness and mechanotransduction in cardiac reprogramming

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

New lipid derivatives of Remdesivir have higher anti-coronavirus activity

Rabbits susceptible to SARS-CoV-2: Red flag for potential virus reservoir

Using SARS-CoV-2 epitope to construct a vaccine

Australia’s readiness for emergencies

SARS-CoV-2 Neucleocapside (N) protein is heavily glycosylated

Severe and fatal COVID-19 is rare in children

Evidence of SARS-CoV-2 spreading in an airplane toilet

FDA announces public meeting to discuss development and licensure of COVID-19 vaccines

Scientists describe known approaches for treatment of SARS-CoV-2 infection

Canada announces $10 million core funding to tackle world water crisis

Race to produce COVID vaccines should not leave the poor left behind, says expert

Researchers delve into marital realities facing women married to professional athletes

Natural disasters alone are not enough to prompt local climate policy change

Sleep restriction may hinder information disclosure during criminal interviews, indicates suggests

Atheists and agnostics more likely to be better sleepers than Catholics, Baptists

Sleep loss unleashes anger, shows study

Clinicians may have to look beyond opioids to tackle nation’s substance use epidemic

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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