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Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

Reducing the delay in neurofeedback can increase the efficacy of training

HSE University scientists have for the first time in the world investigated the impact of delayed reinforcement signals in neurofeedback (NFB) training.

2 Dec 2020

New research project to develop and test novel intervention for individuals with HIV/AIDS

Tulsa CARES is partnering with researchers at the Hudson College of Public Health at the University of Oklahoma Health Sciences Center and the OU-TU School of Community Medicine at the University of Oklahoma to develop and test a novel "food as medicine" intervention for individuals affected by HIV/AIDS.

2 Dec 2020

Study shows how parasite that causes Chagas disease resists current therapies

New insight on how a parasite can resist current therapies has been published today in the open-access eLife journal.

2 Dec 2020

Immune mechanism in COVID-19 patients triggers cytokine storm

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

2 Dec 2020

Study: False widow spiders carry harmful strains resistant to common antibiotic treatments

A team of zoologists and microbiologists from NUI Galway have published a new study showing that common house spiders carry bacteria susceptible to infect people, with the Noble False Widow spiders also carrying harmful strains resistant to common antibiotic treatments.

1 Dec 2020

CARES Act helped reduce social interaction of viral spread

As case rates of COVID-19 reach new heights across the nation, many states and cities are tightening stay-at-home restrictions to stop the spread.

1 Dec 2020

Self-harm among certain primary school-aged children prompts calls for intervention efforts

New research reveals that some primary school-aged children have self-harmed, prompting calls for intervention efforts to start earlier.

1 Dec 2020

Smiling or grimacing can reduce the pain of needle injection by 40%

The coming of winter means cooler temperatures, shorter days and flu shots. While no one looks forward to a vaccination, a study led by the University of California, Irvine, has found that either a sincere smile or a grimace can reduce the pain of a needle injection by as much as 40 percent.

1 Dec 2020

Previously uncharacterized protein regulates mitochondrial NAD transporter

For their growth, cells need various nutrients and vitamins. So-called solute carriers (SLC), proteins that can transport such substances across the boundaries of cellular membranes, play a central role in metabolism.

1 Dec 2020

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

A repurposed mouse model can develop symptoms of both severe COVID-19 (lung damage, blood clots, abnormal blood vessels, and death) and also of milder disease, including loss of the sense of smell, according to a recent University of Iowa study published in Nature.

1 Dec 2020

PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

In an article published in the journal Virus Research, a team of researchers from various US institutions discussed their study that evaluated the antiviral activity of PTC299 against a group of RNA viruses in vitro.

1 Dec 2020

Frequent peak air pollution exposure associated with reduced test scores for third graders

Fine particulate matter (PM2.5), the tiny particles responsible for hazy air pollution, are detrimental to children's health even inside the classroom. Mounting evidence has linked chronic exposure with poor academic performance in K-12 students.

1 Dec 2020

OHDSI awarded $10 million FDA contract to support Biologics Effectiveness and Safety program

Researchers within the Observational Health Data Services and Informatics (OHDSI) community were recently awarded a $10 million contract from the U.S. Food and Drug Administration (FDA) to provide support to the Biologics Effectiveness and Safety (BEST) program, which was launched by the FDA Center for Biologics Evaluation and Research (CBER) in 2017.

1 Dec 2020

Medical News

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

Reducing the delay in neurofeedback can increase the efficacy of training

New research project to develop and test novel intervention for individuals with HIV/AIDS

Study shows how parasite that causes Chagas disease resists current therapies

Immune mechanism in COVID-19 patients triggers cytokine storm

Study: False widow spiders carry harmful strains resistant to common antibiotic treatments

CARES Act helped reduce social interaction of viral spread

Self-harm among certain primary school-aged children prompts calls for intervention efforts

Smiling or grimacing can reduce the pain of needle injection by 40%

Previously uncharacterized protein regulates mitochondrial NAD transporter

Repurposed mouse model sheds light on spectrum of COVID-19 disease symptoms

PTC299 inhibits SARS-CoV-2 replication and suppresses production of inflammatory cytokines

Frequent peak air pollution exposure associated with reduced test scores for third graders

OHDSI awarded $10 million FDA contract to support Biologics Effectiveness and Safety program

Cleaning surfaces with hydrogen peroxide-based disinfectants may pollute indoor air

Three leading organizations join hands to address global challenges in dementia

Microfiber- and nanofiber-based wearable monitors could keep track of patient’s vital signs

MU researcher identifies resources to assist overburdened family caregivers

Alcohol-free hand sanitizer works just as well as alcohol-based products to control COVID-19

COVID-19 may exacerbate mental health symptoms among pregnant and postpartum women

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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