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Women and minorities inadequately represented in clinical trials for novel cardiometabolic drugs

Women and minorities, particularly African Americans, continue to be inadequately represented in clinical trials for novel cardiometabolic medications, with no evidence of improvement in enrollment numbers over the past decade, according to new research published last week in the Journal of the American Heart Association, an open-access journal of the American Heart Association.

28 May 2020

Transgenic mouse model of HLH may play key role in saving lives during COVID-19

A transgenic mouse developed at Cincinnati Children's to model the deadly childhood immune disease HLH (hemophagocytic lymphohistiocytosis) may play a key role in saving lives during the COVID-19 virus pandemic.

28 May 2020

Physical activity prevents the accumulation of damaged proteins and keeps muscles healthy

Researchers at the University of Copenhagen's Department of Nutrition, Exercise and Sports have demonstrated that physical activity prompts a clean-up of muscles as the protein Ubiquitin tags onto worn-out proteins, causing them to be degraded.

28 May 2020

Clinical study shows promising results for treatment of VHL disease-associated renal tumors

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted in clinical responses for patients with von Hippel-Lindau disease (VHL)–associated renal cell carcinoma.

28 May 2020

Type 2 diabetes is more prevalent in American Indians and Alaska Natives

Type 2 diabetes (T2D) affects American Indians and Alaska Natives at approximately three times the rate of white Americans and is closely linked to the disproportionately high rates of cardiovascular diseases such as heart attacks and strokes, according to the American Heart Association Scientific Statement "Cardiovascular Health in American Indians and Alaska Natives," published today in the Association's flagship journal Circulation.

28 May 2020

New device allows rapid disease analysis in kidneys affected by diabetes

The amount of scarring in damaged kidneys as a result of diabetes or acute injury, is a key factor in determining treatment. But it has not been possible, using traditional techniques, to quickly and accurately assess how widespread this kind of wounding extends within the organ.

28 May 2020

Some ivory towers are ideal for a pandemic. Most aren’t.

Saint Mary's College in Moraga, California, is open for business this fall — but to get there, you really have to want it. Tucked amid verdant hills 23 miles east of San Francisco, accessible by a single road and a single entrance, the small, private Roman Catholic school receives almost no visitors by accident.

28 May 2020

Nearly 50% of COVID-19 patients have altered sense of tastes

Nearly half of individuals who contract COVID-19 experience changes in their sense of taste, a new analysis led by a University of Toledo researcher has found.

28 May 2020

New framework for assessing and managing people with serious spinal pathologies

Rehabilitation clinicians and other health care professionals now have a framework for assessing and managing people who may have serious spinal pathologies.

28 May 2020

Early exposure to anesthetics may cause alcohol use disorder in adolescents

Early exposure to anesthetics may make adolescents more susceptible to developing alcohol use disorder (AUD), according to new research from Binghamton University, State University of New York.

28 May 2020

Searching for safety: Where children hide when gunfire is all too common

Champale Greene-Anderson keeps the volume up on her television when she watches 5-year-old granddaughter Amor Robinson while the girl's mom is at work.

28 May 2020

For seniors, COVID-19 sets off a pandemic of despair

As states relax coronavirus restrictions, older adults are advised, in most cases, to keep sheltering in place. But for some, the burden of isolation and uncertainty is becoming hard to bear.

28 May 2020

New project launched to find novel treatments for rare genetic diseases

The University Carlos III Madrid, Almirall, S.A. and the MEDINA Foundation have launched a project to find new treatments for recessive dystrophic epidermolysis bullosa and other genetic diseases caused by nonsense mutations.

28 May 2020

Antibody tests were hailed as way to end lockdowns. Instead, they cause confusion.

Aspen was an early COVID-19 hot spot in Colorado, with a cluster of cases in March linked to tourists visiting for its world-famous skiing. Tests were in short supply, making it difficult to know how the virus was spreading.

28 May 2020

Studies advance the understanding of sensory disconnection during sleep and anesthesia

During sleep and under anesthesia, we rarely respond to such external stimuli as sounds even though our brains remain highly active.

28 May 2020

Fluctuating estrogen levels could make alcohol more rewarding to women

Fluctuating estrogen levels may make alcohol more rewarding to female mice, according to new research in JNeurosci. Untangling the involved signaling pathways could unveil sex-based treatments for alcohol use disorders.

28 May 2020

Molecular signatures can predict outcome of sepsis patients based on their immune response

Scientists have identified molecular signatures in the immune component of the blood which indicate how patients in intensive care with sepsis, septic shock and systemic inflammatory response syndrome are likely to respond to the conditions.

28 May 2020

Shandong University offers high-tech support to fight against coronavirus epidemic

Since the COVID-19 outbreak, the SDU-NTU Joint Centre for Artificial Intelligence Research has developed two types of robots, which were sent to hospitals in Wuhan and Huanggang in China’s Hubei Province to aid front-line fight against the coronavirus epidemic.

28 May 2020

Monash study confirms new approach to measure consciousness

An international study involving Monash physicists has confirmed a new approach to measure consciousness, potentially changing our understanding complex neurological problems.

28 May 2020

Digital platform can help reduce healthcare-related infections in surgical environments

One in ten people in hospital care develops a healthcare-related infection. Together with Getinge, Semcon is developing a new digital platform to make it easier to identify where the risk of infections during surgery is greatest.

28 May 2020

Medical News

Women and minorities inadequately represented in clinical trials for novel cardiometabolic drugs

Transgenic mouse model of HLH may play key role in saving lives during COVID-19

Physical activity prevents the accumulation of damaged proteins and keeps muscles healthy

Clinical study shows promising results for treatment of VHL disease-associated renal tumors

Type 2 diabetes is more prevalent in American Indians and Alaska Natives

New device allows rapid disease analysis in kidneys affected by diabetes

Some ivory towers are ideal for a pandemic. Most aren’t.

Nearly 50% of COVID-19 patients have altered sense of tastes

New framework for assessing and managing people with serious spinal pathologies

Early exposure to anesthetics may cause alcohol use disorder in adolescents

Searching for safety: Where children hide when gunfire is all too common

For seniors, COVID-19 sets off a pandemic of despair

New project launched to find novel treatments for rare genetic diseases

Antibody tests were hailed as way to end lockdowns. Instead, they cause confusion.

Studies advance the understanding of sensory disconnection during sleep and anesthesia

Fluctuating estrogen levels could make alcohol more rewarding to women

Molecular signatures can predict outcome of sepsis patients based on their immune response

Shandong University offers high-tech support to fight against coronavirus epidemic

Monash study confirms new approach to measure consciousness

Digital platform can help reduce healthcare-related infections in surgical environments

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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