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Targeted drugs shrink breast cancer tumors in mice without toxic side effects

A team of researchers led by Worcester Polytechnic Institute Provost Wole Soboyejo has identified targeted drugs that reduced the sizes of hard-to-treat breast cancer tumors in mice without inducing the toxic side effects that are typically associated with conventional chemotherapy.

28 May 2020

Temple research suggests new way to prevent abdominal aortic aneurysm therapeutically

The main thoroughfare that carries oxygen-rich blood from the heart to the abdomen is known as the abdominal aorta.

28 May 2020

Study provides groundwork for restoring nerve-muscle connection in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

28 May 2020

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

A new study published on the online preprint server bioRxiv in May 2020 reports the construction and testing of a new ferritin-based antigen-bearing protein that has biological activity towards the ACE2 receptor. This could indicate its potential for development as a vaccine or antiviral.

28 May 2020

$Study finds increase in pediatric fractures sustained at home during COVID-19 pandemic$

Study finds increase in pediatric fractures sustained at home during COVID-19 pandemic

COVID-19 social distancing measures, including the closure of schools and parks and the indefinite cancellation of team sports, have led to a nearly 60% decrease overall in pediatric fractures but an increase in the proportion of fractures sustained at home, according to a new study by researchers at Children's Hospital of Philadelphia.

28 May 2020

Study finds gender differences in autism severity changes during early childhood

During early childhood, girls with autism tend to show greater reduction and less rise in their autism symptom severity than boys with autism, a UC Davis MIND Institute study has found.

28 May 2020

Pitt researcher to explore the neurological sex-based divide in dementia

Fifty million people worldwide are living with dementia, a broad term for diseases and conditions characterized by progressive cognitive decline.

28 May 2020

PCR and CRF partner to deliver practical education in virtual format

PCR and CRF are pleased to announce the creation of virtual Partners in Learning sessions that will be broadcast during the PCR e-Course (June 25-27, 2020) and CRF’s TVT Connect meeting (June 18-28, 2020).

28 May 2020

Experts issue new guidance to improve stroke care amid COVID-19

Top stroke experts have issued new guidance to ensure stroke patients receive safe, timely care while preventing the transmission of COVID-19.

28 May 2020

A closer look at TMPRSS2: This could help treat COVID-19

The transmembrane protease serine-type 2 (TMPRSS2) protein plays a key role in COVID-19 infection since it primes the viral spike protein to allow viral entry into the target cell. A new study by researchers at Imperial College London and published on the preprint server bioRxiv in May 2020 describes the protein, which could be an attractive drug target to help manage COVID-19.

28 May 2020

Inhibiting tumor signals can suppress the spread of cancer

For most people who die of cancer, the spread of the initial tumor is to blame. "Metastasis is what kills most cancer patients," says Serge Fuchs, a professor in Penn's School of Veterinary Medicine.

28 May 2020

CBD treatment improves arthritis symptoms in dogs, study finds

A team led by researchers at Baylor College of Medicine in collaboration with Medterra CBD conducted the first scientific studies to assess the potential therapeutic effects of cannabidiol for arthritic pain in dogs, and the results could lead the way to studying its effect in humans.

28 May 2020

KHN’s ‘What the Health?’: Still seeking a federal coronavirus strategy

The Trump administration sent its COVID-19 testing strategy plan to Congress, formalizing its policy that most testing responsibilities should remain with individual states.

28 May 2020

Research provides important insights into genetic adaptation of SARS-CoV-2 to humans

In their groundbreaking paper available on the preprint server medRxiv, University of Pittsburgh researchers were appraising signals of SARS-CoV-2 genome evolution and found that purifying selection (i.e., removal of deleterious mutations) represents the dominant trait during early coronavirus disease (COVID-19) pandemic - suggesting that the virus will evolve as it diversifies in a growing number of hosts.

28 May 2020

Johns Hopkins team develops new method to maintain sufficient supplies of kidney dialysis fluid

The ongoing COVID-19 pandemic has severely impacted the manufacturing and supply chains for many products.

28 May 2020

New drug combinations could help overcome genetic immunotherapy resistance

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way.

28 May 2020

Researchers study the effect of major life events on wellbeing

Major life events such as marriage, death of a loved one or bankruptcy all affect our wellbeing. Now, for the first time, researchers have compared the differing impact of these events on the happiness and life satisfaction and how long that impact lasts.

28 May 2020