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New therapeutic approach for preserving inflammation-free phases of Crohn's disease

Intestinal stem cell metabolism is facilitated by mitochondria - the in-cell power plants. Chronic inflammation processes inhibit the cells' metabolism and lead to functional loss of these stem cells.

15 Apr 2020

European Commission issues guidelines on coronavirus testing methodologies

Today, as part of the European Roadmap towards lifting coronavirus containment measures, the Commission is presenting guidelines on coronavirus testing methodologies.

15 Apr 2020

Remdesivir drug stops novel coronavirus from replicating

Scientists from the University of Alberta have published findings that the antiviral drug remdesivir prevents replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by inhibiting RNA replication. The study, published in April 2020 in the Journal of Biological Chemistry, follows on the heels of earlier reports from the same lab in February, showing the drug's effectiveness against the related Middle East Respiratory Syndrome (MERS) virus.

15 Apr 2020

Depression, anxiety may be side effects of COVID-19 pandemic

Millions of Americans are being impacted by the psychological fallout from the COVID-19 pandemic and its economic aftermath, and large numbers may experience emotional distress and be at increased risk of developing psychiatric disorders such as depression and anxiety, according to a new article published this week in the New England Journal of Medicine.

15 Apr 2020

Researchers explore how probiotic Bifidobacteria could help celiac disease patients

Gluten is enemy No. 1 for those with celiac disease, and it's hard to avoid. Episodes of this chronic autoimmune illness can be triggered by ingesting gluten, a key protein in wheat and some other grains.

15 Apr 2020

Anosmia (loss of smell) confirmed as a clinical feature of COVID-19

Earlier last month, the association of ear, nose, and throat (ENT) specialists in the UK issued a public statement advising patients with a sudden loss of smell or taste to get tested for COVID-19. They cited not only their own observations but those from numerous other ENT consultants the world around. A review of multiple papers on the sinus and nasal symptoms and signs related to the diagnosis of COVID-19, published in April 2020, in the journal Laryngoscope Investigative Otolaryngology, reiterates this finding.

15 Apr 2020

New drug preserves cognitive function in mice after brain irradiation

A study by researchers at the UCLA Jonsson Comprehensive Cancer Center has identified a possible new drug that could help prevent cognitive decline in people who undergo radiation therapy for brain tumors.

15 Apr 2020

Alzheimer's patients may need modified dosing regimens for selected drugs

Patients with Alzheimer's disease are often prescribed drugs for other conditions -- including diabetes or high blood pressure -- at the same doses as those without dementia.

15 Apr 2020

Aspirin associated with reduction in risk of several digestive tract cancers

Aspirin is associated with a reduction in the risk of developing several cancers of the digestive tract, including some that are almost invariably fatal, such as pancreatic and liver cancers.

15 Apr 2020

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

15 Apr 2020

New grant aims to develop digital tools for assessing patients with cardiovascular disease

A new grant will fund an international collaboration to develop tools to assess patients who suffer from cardiovascular disease.

15 Apr 2020

Review: The effect of probiotics in ameliorating altered CNS functions in neurological disorders

As per the WHO report, one in every four people are affected by a mental or neurological disorder at some point in their lives making mental disorders among the leading cause of ill-health and disability worldwide.

15 Apr 2020

High-resolution imaging with elastography could accurately spot breast cancer in surgical margins

A high-resolution, three-dimensional imaging technique, when combined with quantitative measurement of tissue elasticity, could accurately detect cancer within the resected margins of surgical specimens taken from patients undergoing breast-conserving surgery.

15 Apr 2020

Coronavirus able to survive near boiling point of water, study shows

A startling paper by a team of French scientists published in the preprint journal bioRxiv in April 2020 suggests that the novel coronavirus is capable of surviving at high temperatures. This could mean that laboratory technicians handling the virus are at danger of infection.

15 Apr 2020

Young people cite barriers to seeking help for eating disorders

A new study has found young people are leaving it 'too late' to seek help for eating disorders, citing fear of losing control over their eating or weight, denial, and failure to perceive the severity of the illness as reasons not to get professional advice.

15 Apr 2020

Unexpected benefit of COVID-19 lockdowns on the environment and health

The pandemic spreading over the world has affected over 185 countries and territories so far, with over 2 million cases and 134,354 deaths. In response, many countries and regions have enforced lockdowns, in addition to the almost universal recommendations for social distancing. One of the most significant impacts has been the effect on economic activity the world over.

15 Apr 2020

Vegetable intake before pregnancy reduces risk of preterm birth

A new study shows that women who eat vegetables regularly before becoming pregnant have a significantly lower risk of premature birth. The new study from the University of Queensland titled, "Prepregnancy dietary patterns and risk of preterm birth and low birth weight: findings from the Australian Longitudinal Study on Women's Health," was published in the latest issue of the journal The American Journal of Clinical Nutrition.

15 Apr 2020

Australian researchers split ventilators for COVID-19

Australian researchers have found that in cases of “extreme emergencies,” a single ventilator could be used between multiple patients of COVID-19 who require ventilator support. These ventilators could be split between the critically ill patients with not only COVID-19 but also other respiratory illnesses, the team of Australian researchers found. The study titled, “'Ventilator splitting with differential driving pressures using commodity hospital equipment,” was published in the latest issue of the journal Anaesthesia.

15 Apr 2020

COVID-19 modeling shows that social distancing is a must, must, must

A new study shows that using mathematical modeling and accounting for several factors such as age distribution and density of the population, a clearer picture of COVID-19 infection in a population could be gained. The study titled, "Level of under-reporting including under-diagnosis before the first peak of COVID-19 in various countries: Preliminary Retrospective Results Based on Wavelets and Deterministic Modeling," is published as an accepted manuscript in the journal Infection Control & Hospital Epidemiology.

15 Apr 2020

New coronavirus possibly circulated within humans before COVID-19 pandemic

Genetic variation analysis and the evidence of recombination events point towards the conclusion that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might have circulated cryptically among humans for years, as reported by a recent paper on a preprint server bioRxiv.

15 Apr 2020