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'Mini-brains' can be infected by SARS-CoV-2 virus

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.

30 Jun 2020

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown.

30 Jun 2020

Potential new biomarker could improve COVID-19 diagnosis

Researchers at Montpellier University Hospital have discovered that an interferon-inducible receptor expressed on monocytes could be a useful biomarker for the rapid triaging of patients suspected to have severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

30 Jun 2020

In-home portable air cleaners reduce particulate exposure for cardiac patients

Using an in-home portable air cleaner (PAC) can significantly reduce exposure to fine-particle air pollutants - a major risk factor for cardiovascular events in people with pre-existing heart disease, reports a pilot study in the July issue of Journal of Cardiopulmonary Rehabilitation and Prevention.

30 Jun 2020

New study will help primary care nurses better care for dementia patients

McLean Hospital's Brent P. Forester, MD, MSc, is heading a new study of a training model to help primary care nurses better care for patients with dementia.

30 Jun 2020

Alternative antibiotics for unverified penicillin allergies likely unnecessary

Hospitalized patients who report an allergy to penicillin are often prescribed alternative antibiotics for infection that can be harmful, even though diagnostic testing or evaluations would show that the vast majority of these reported allergies could be disproven, according to researchers from Massachusetts General Hospital.

30 Jun 2020

Novel brain pathology could improve diagnosis, treatment of neurodegenerative diseases

Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease.

30 Jun 2020

A semi-empirical model to reproduce the brain states from wakefulness to deep sleep

The human brain is a complex system comprising 1010 non-linear units (neurons) that interact in 1015 sites (synapses).

30 Jun 2020

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

Cancer cases have been rising over the years and according to the statistics, the number of people living with cancer will continue to increase.

30 Jun 2020

Survey: 47% of people use technology to communicate with their healthcare providers

New research shows that 47 percent of people are using technology to communicate with their healthcare providers, and less than a quarter are having conversations with their providers about using health information technology (HIT).

30 Jun 2020

Ghana's efforts to eliminate malaria at risk as economy improves

Ghana's efforts to eliminate malaria could be in jeopardy as its improved economy results in reduced external funding for fighting malaria, a study suggests.

30 Jun 2020

Researchers uncover a potentially promising strategy to target brain tumors

Gliomas with mutations in what are called the isocitrate dehydrogenase (IDH) genes are the most common brain tumors diagnosed in younger adults aged 18 to 45 years.

30 Jun 2020

SARS-CoV-2 can infect heart cells in a lab dish, study shows

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

30 Jun 2020

A biocompatible polymer can help heal broken bones

Healing broken bones could get easier with a device that provides both a scaffold for the bone to grow on and electrical stimulation to urge it forward, UConn engineers reported on June 27 in the Journal of Nano Energy.

30 Jun 2020

The biggest database for automated gait analysis

The database comprises information on the so-called "ground reaction force" which is the force between the foot and the ground that is generated during movement. It is an important standard parameter used in clinical practice and in research.

30 Jun 2020

Foldable tent-like device shields healthcare workers caring for COVID-19 patients

A team of researchers from the National University of Singapore has invented a foldable tent-like device that serves as a physical shield to reduce the risk of exposure to pathogens for healthcare workers performing droplet and aerosol-generating procedures on COVID-19 patients.

30 Jun 2020

COVID-19 triggers changes in blood platelets

Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease, according to University of Utah Health scientists.

30 Jun 2020

Novel vaccine that removes aged immune cells mitigates metabolic disorders in obese mice

Aging is a multifaceted process that affects our bodies in many ways. In a new study, researchers from Osaka University developed a novel vaccine that removes aged immune cells and then demonstrated an improvement of diabetes-associated metabolic derangements by vaccinating obese mice.

30 Jun 2020

Residents of some cities unwilling to follow practices that reduce COVID-19 spread

Several U.S. cities may be at increased risk of surges in COVID-19 cases as they reopen their economies because their residents are unwilling to follow practices that reduce the spread of the disease, according to Penn State researchers.

30 Jun 2020

Stool microbial and metabolite signatures predict cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to cirrhosis, liver cancer, liver failure and death.

30 Jun 2020

Medical News

'Mini-brains' can be infected by SARS-CoV-2 virus

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

Potential new biomarker could improve COVID-19 diagnosis

In-home portable air cleaners reduce particulate exposure for cardiac patients

New study will help primary care nurses better care for dementia patients

Alternative antibiotics for unverified penicillin allergies likely unnecessary

Novel brain pathology could improve diagnosis, treatment of neurodegenerative diseases

A semi-empirical model to reproduce the brain states from wakefulness to deep sleep

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

Survey: 47% of people use technology to communicate with their healthcare providers

Ghana's efforts to eliminate malaria at risk as economy improves

Researchers uncover a potentially promising strategy to target brain tumors

SARS-CoV-2 can infect heart cells in a lab dish, study shows

A biocompatible polymer can help heal broken bones

The biggest database for automated gait analysis

Foldable tent-like device shields healthcare workers caring for COVID-19 patients

COVID-19 triggers changes in blood platelets

Novel vaccine that removes aged immune cells mitigates metabolic disorders in obese mice

Residents of some cities unwilling to follow practices that reduce COVID-19 spread

Stool microbial and metabolite signatures predict cirrhosis

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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