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New evidence shows that type 1 diabetes is not one but two separate conditions

Children who are diagnosed with type 1 diabetes under the age of seven have a different form (or "endotype") of the condition compared with those diagnosed aged 13 or above, new research has shown.

15 Mar 2020

Type 1 diabetes mellitus comprises of two different conditions based on age

A new study published in the journal Diabetologia in March 2020 reports that children aged below seven years with type 1 diabetes mellitus (T1DM) have a distinct form of the condition from children aged 13 or more.

15 Mar 2020

Chest CT shows COVID-19 damage to the lungs

A new study presents peer-reviewed cases of COVID-19 in order to ensure that the disease is diagnosed as rapidly as possible, and thus help prevent an overwhelming spike in infections in any one place during the course of the current pandemic. Much interest has been shown in the possibility of using chest X-rays, and computed tomography (CT) scans to screen for and diagnose patients with this illness, whether suspected or confirmed.

15 Mar 2020

Are opioids necessary after tooth extraction?

A new study published in the journal JAMA Network Open in March 2020 shows that dentists can eliminate opioid analgesia from their armory of pain reliever after a tooth extraction, or at least dramatically reduce its use.

15 Mar 2020

Suicidal ideation seen in 8 percent of kids says study

According to an alarming new report from the American researchers, 8.4 percent of the children aged between 9 and 10 years are temporarily or regularly thinking about suicide or considering and planning suicide. This study that included 7,994 children was titled, "Risk and protective factors for childhood suicidality: A US population-based study" and was published in the latest issue of The Lancet Psychiatry journal.

15 Mar 2020

Reports of flu-like symptoms seen with Keto diet

A new study has shown that those starting on a keto diet could develop certain flu-like symptoms in the initial weeks. The study titled, “Consumer Reports of “Keto Flu” Associated With the Ketogenic Diet,” was published in the latest issue of the journal Frontiers in Nutrition.

15 Mar 2020

Reusing masks may increase your risk of coronavirus infection, expert says

Panic buying and the hoarding of face masks to protect from the coronavirus disease (COVID-19) may not be a good idea, says a health expert. It puts you at an increased risk of contracting the virus.

15 Mar 2020

Alzheimer's and its helper protein

It is commonly observed that the brain in patients with Alzheimer's disease (AD) often contains fibrils of tau protein, which build up within the brain neurons to interrupt proper communication between them. However, it is far from clear what these deposits mean and how they form.

15 Mar 2020

Drosophila flies lose long-term memory of traumatic event when kept in the dark, study shows

Scientists from Tokyo Metropolitan University have discovered that Drosophila flies lose long-term memory of a traumatic event when kept in the dark, the first confirmation of environmental light playing a role in LTM maintenance.

14 Mar 2020

Administering specialized lipids prevents memory loss, inflammation in Down syndrome mouse model

Individuals with Down syndrome are at a much greater risk of developing Alzheimer's disease, with inflammation of the brain starting early in life and the risk of Alzheimer's reaching nearly 80% by the age of 60.

13 Mar 2020

Bacteria multiply and grow into biofilms like settlers form cities

Microbiologists have long adopted the language of human settlement to describe how bacteria live and grow: They "invade" and "colonize." Relations dwelling in close proximity are "colonies."

13 Mar 2020

Study provides insights on evaluating hypertension in children

Results from a new study provide insights on evaluating high blood pressure in children. The findings appear in an upcoming issue of CJASN.

13 Mar 2020

Testing shortages force extreme shift in strategy by local health officials

Public health officials in California's state capital region announced this week they have stopped tracing the contacts of patients diagnosed with the novel coronavirus. They've also ceased recommending quarantines for residents exposed to people confirmed to have the virus.

13 Mar 2020

Researchers engineer microparticles that show promise against transplant rejection

Inspired by a tactic cancer cells use to evade the immune system, University of Pittsburgh researchers have engineered tiny particles that can trick the body into accepting transplanted tissue as its own.

13 Mar 2020

Looking for answers after coronavirus contact? Welcome to the gray zone

Liz Lucas got a call Tuesday afternoon from a friend she'd interacted with closely at a journalism conference in New Orleans days earlier who had tested presumptively positive for coronavirus. She wondered what this meant for her and those around her, so she reached out to local and state health officials in Missouri for guidance.

13 Mar 2020

Experts call for older people to be considered in global responses to coronavirus

Current guidance on coronavirus “largely ignores” the implications for public health and clinical responses in light of those most at risk, according to an international group of global health experts.

13 Mar 2020

Overview of prognostic and predictive factors in pancreatic cancer

Oncotarget Volume 11, Issue 10 reported that there are not standardized predictive biomarkers able to identify patients who benefit most from treatments.

13 Mar 2020

A miRNA signature linked to local-regional failure and overall survival after pancreatic cancer resection

The cover for issue 10 of Oncotarget features Figure 3, "Overall survival (OS) for high (red) versus low (black) risk groups in the (A) OSU, (B) TCGA, and (C) SNU resected cohorts," by Wolfe, et al.

13 Mar 2020

MicroRNA dysregulation has critical impacts on development, inflammation and cancer development

Oncotarget Volume 11, Issue 10 reported that dysregulation of noncoding micro RNA molecules has been associated with immune cell activation in the context of Helicobacter pylori-induced gastric inflammation as well as carcinogenesis, but also with downregulation of mismatch repair genes, and may interfere with immune checkpoint proteins that lead to the overexpression of antigens on gastric tumor cells.

13 Mar 2020

Characterization of DNAm status of MMPs and TIMPs in atheromatous plaques

Oncotarget Volume 11, Issue 10 reported that the statistically associated Cp G sites were analyzed in blood samples from two separate atherothrombotic stroke cohorts, ischemic stroke-cohort 1: 37 atherothrombotic patients and 6 controls, ischemic stroke-cohort 2: 80 atherothrombotic patients and 184 controls.

13 Mar 2020