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New clinical trial to examine the safety of dapivirine vaginal ring and PrEP in pregnant women

The first clinical trial specifically designed to test the safety of the monthly dapivirine vaginal ring in pregnant women has begun in southern and eastern Africa.

10 Feb 2020

Statin use alone or with metformin may increase survival in high-risk prostate cancer patients

Among high-risk prostate cancer patients - those with high PSA and Gleason scores of 8 or more - many will develop a difficult-to-treat disease.

10 Feb 2020

Clinical trial of two investigational drugs for rare, inherited Alzheimer's yields disappointing results

An international clinical trial evaluating whether two investigational drugs can slow memory loss and cognitive decline in people in the early stages of a rare, inherited form of Alzheimer's disease has yielded disappointing results, an initial analysis of the data has shown.

10 Feb 2020

Novel innate immunity factor inhibits HIV infection by targeting lipid rafts, study finds

The human protein apolipoprotein A-I binding protein inhibits HIV replication by targeting lipid rafts and reducing virus-cell fusion, according to a new study published in the premier American Society for Microbiology journal mBio by researchers from the George Washington University.

10 Feb 2020

Researchers simulate leaky gut conditions using 3D models of human intestines

Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut" -- in which microbes and other molecules seep out of the intestines -- may be more common, and more harmful, than previously thought.

10 Feb 2020

New treatment effective at reversing the manifestations of thyroid eye disease

Patients with thyroid eye disease who used the minimally invasive insulin-like growth factor I blocking antibody, teprotumumab, experienced improvement in their symptoms, appearance and quality of life, according to a study recently published in the New England Journal of Medicine.

10 Feb 2020

Youth with HIV have lower rates of viral suppression than adults

Despite similar rates of enrollment into medical care, youth with HIV have much lower rates of viral suppression--reducing HIV to undetectable levels--compared to adults, according to an analysis funded by the National Institutes of Health.

10 Feb 2020

Common drug could mitigate risk of 'a broken heart' during bereavement

The increased risk of heart attack or "a broken heart" in early bereavement could be reduced by using common medication in a novel way, according to a world-first study led by the University of Sydney and funded by Heart Research Australia.

10 Feb 2020

WHO and FIND formalize strategic collaboration to close major diagnostic gaps

The World Health Organization and the Foundation for Innovative New Diagnostics announced today that a memorandum of understanding has been signed by the two organizations to formalize a strategic collaboration that will strengthen diagnosis in resource-poor countries by closing major diagnostic gaps at country level and bolstering disease surveillance that will inform public health initiatives and enhance outbreak preparedness and response.

10 Feb 2020

Vision Engineering to showcase innovative new products at Southern Manufacturing & Electronics show

Vision Engineering, the leading manufacturer of high-quality visual inspection and measurement technologies, will return to the Southern Manufacturing & Electronics show in Farnborough this month, to exhibit some of its brand new technologies and products, including: the TVM, the Deep Reality Viewer (DRV-Z1), LVC400 and new EVO Cam II firmware.

From Vision Engineering Limited 10 Feb 2020

Outcomes-based drug reimbursement may be on the horizon, report says

How can pharma and life sciences be prepared and agile enough to respond to future challenges if it has not thought about the current trends and emerging challenges?

10 Feb 2020

InterSystems deploys TrakCare with novel coronavirus screening functionality

InterSystems is releasing global functionality for its TrakCare unified healthcare information system to screen and support patients with 2019-nCoV, the novel coronavirus infection that originated in Wuhan in China.

10 Feb 2020

Higher maternal blood pressure linked to placental gene modifications

Higher maternal blood pressure in pregnancy is associated with chemical modifications to placental genes, according to a study by researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health.

10 Feb 2020

Protein Data Bank archive releases new coronavirus protease structure

The Protein Data Bank archive, which contains more than 160,000 3D structures for proteins, DNA, and RNA, this month released a new Coronavirus protease structure following the recent coronavirus outbreak, an ongoing viral epidemic primarily affecting mainland China that now threatens to spread to populations in other parts of the world.

10 Feb 2020

How lifesaving organs for transplant go missing in transit

When a human heart was left behind by mistake on a Southwest Airlines plane in 2018, transplant officials downplayed the incident. They emphasized that the organ was used for valves and tissues, not to save the life of a waiting patient, so the delay was inconsequential.

10 Feb 2020

Single dose of HPV vaccine is effective for preventing preinvasive cervical disease

New research indicates that a single dose of the human papillomavirus vaccine is as effective as multiple doses for preventing preinvasive cervical disease, which can later develop into cervical cancer.

10 Feb 2020

Quick reference points on egg freezing for age-related fertility

Egg freezing for age-related fertility is becoming more common, and a short article in CMAJ provides quick reference points on the topic for primary care providers.

10 Feb 2020

Study uncovers new avenue for melanoma diagnosis and therapies

A new way to spot melanoma cells circulating in the blood has the potential to significantly improve the monitoring of cancer patients and guide future treatment.

10 Feb 2020

Research reveals novel way to treat cancers using CAR T cell therapy

Too many patients with cancers like multiple myeloma relapse after treatment. This grim reality motivated researchers at Huntsman Cancer Institute at the University of Utah to try to improve the depth and durability of treatment response in multiple myeloma through a new cancer cell targeting mechanism.

10 Feb 2020

UK facing a major coronavirus outbreak, experts warn

The novel coronavirus (2019-nCoV or Wuhan coronavirus) is spreading like wildfire across the globe and health officials are racing to contain the virus. Experts in the United Kingdom warn that the country is facing a major coronavirus outbreak in the coming weeks as the number of confirmed cases rises to four, as more than 25 countries have reported increasing case toll.

9 Feb 2020