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Review highlights calcium handling mechanisms involved in reperfusion injury

Stroke and myocardial infarction (MI) are a significant cause of death and disability worldwide. However, over the past several decades because of advances in medicines (thrombolytic agents, antiplatelet drugs, beta blockers, and angiotensin converting enzyme inhibitors) and approaches to restore tissue perfusion (percutaneous coronary intervention and cardiopulmonary bypass), the mortality of MI has declined dramatically.

20 Dec 2018

WU biomedical engineer makes a significant step toward precision medicine

In 2015, then President Barack Obama launched a precision medicine initiative, saying that its promise was "delivering the right treatments, at the right time, every time to the right person.

20 Dec 2018

Stress related pathway instrumental in controlling function of immune cells

The immune system is composed of a wide range of different immune cells each with dedicated functions. Natural killer T cells form a specialized immune cell that protects against a variety of diseases such as cancer, autoimmunity, metabolic disease or certain infections such as Lyme disease.

20 Dec 2018

IASLC’s ELIC pilot project develops innovative technique for improving early lung cancer detection

Evidence proves that screening saves lives, with screening for breast, colon, prostate and cervical cancers, for example, being accepted in many parts of the world as a routine part of medical care.

20 Dec 2018

UNH study offers insight into lasting impact of concussions on young adults

Researchers at the University of New Hampshire have found that young adults who experienced repetitive mild traumatic brain injury, or concussions, can experience persistent cognitive changes as well as altered brain activity.

20 Dec 2018

New communication strategies can help spread the word about cancer screening

Is there ever a truly good time for a colonoscopy? Even with the recommendation of a primary care physician, it's easy to procrastinate or simply forget to schedule an appointment with your friendly neighborhood endoscopist.

19 Dec 2018

Study finds how pyruvate helps improve cardiac output in pediatric patients with LCOS

Can pyruvate, the end product of glycolysis, help improve cardiovascular function in children who have cardiopulmonary bypass surgery and suffer from low cardiac output syndrome? This question is one that Rafael Jaimes, Ph.D., a staff scientist at Children's National Heart Institute, a division of Children's National Health System, is studying, thanks to a two-year grant from the American Heart Association.

19 Dec 2018

Tau protein reduces neural activity in Alzheimer's mouse models

A study from Massachusetts General Hospital investigators sheds new light on how the hallmarks of Alzheimer's disease - amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau - produce their damaging effects in the brain.

19 Dec 2018

FAU Brain Institute fellows awarded $1.1 million for Alzheimer's disease research

In Florida, there are more than 540,000 people living with Alzheimer's disease (AD), the most recognized form of dementia. The number of people in Florida who are age 65 and older with AD is expected to increase 41.2 percent by 2025 to a projected 720,000, highlighting the urgency of finding medical and treatment breakthroughs.

19 Dec 2018

New study uses intracranial recordings to investigate memory development

Declarative memory -- memories that can be consciously recalled -- is critical to everyday life. Throughout childhood and adolescence, declarative memory improves remarkably. However, until most recently, there was a critical gap in our understanding of how maturation of the prefrontal cortex drives memory development.

19 Dec 2018

$Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction$

Type 2 diabetes drug may be used to treat heart failure with preserved ejection fraction

Researchers at the University of Arizona have discovered that metformin, a drug commonly used to treat type 2 diabetes, might also be used to treat heart failure with preserved ejection fraction, a condition that is predicted to affect over 8% of people ages 65 or older by the year 2020.

19 Dec 2018

MUSC researchers identify potential therapeutic target for lung fibrosis

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or scarring.

19 Dec 2018

Viral hepatitis: Liver failure caused by defects in the vascular system

In severe cases, a viral hepatitis infection can result in liver failure. A team from the Technical University of Munich has now discovered how this occurs: by immune cells attacking cells in the vascular system, which disrupts the organ's blood and nutrient supply.

19 Dec 2018

Women who were born small may be at increased risk of pregnancy complications

Women who were born with a low birthweight are at increased risk of pregnancy complications, according to a new Obesity study. The findings suggest that women who were born small may have been affected by unfavorable intrauterine conditions, and the physiological demands of pregnancy may act as a "second hit" leading to pregnancy complications.

19 Dec 2018

Obesity help on the front line

The Australian National University (ANU) has developed a new program to be rolled out across the country to help GPs treat patients with obesity.

19 Dec 2018

Vaping surges among American teenagers says new report

A latest report finds that United States teenagers are increasingly using e-cigarettes also known as vapes. These electronic cigarettes were initially targeted towards adults who were willing to quit smoking.

19 Dec 2018

Self-powered bandage generates electricity, reduces healing time for skin wounds in rats

Skin has a remarkable ability to heal itself. But in some cases, wounds heal very slowly or not at all, putting a person at risk for chronic pain, infection and scarring. Now, researchers have developed a self-powered bandage that generates an electric field over an injury, dramatically reducing the healing time for skin wounds in rats.

19 Dec 2018

GABA cells help fight alcohol dependence, study finds

Scientists of the Higher School of Economics, Indiana University, and École normale supérieure clarified how alcohol influences the dopamine and inhibitory cells in the midbrain that are involved in the reward system and the formation of dependency on addictive drugs.

19 Dec 2018

KU Leuven scientists develop new vaccine against Zika virus

Scientists at the KU Leuven Rega Institute in Belgium have developed a new vaccine against the Zika virus. This vaccine should prevent the virus from causing microcephaly and other serious conditions in unborn babies.

19 Dec 2018

Loss of vision has considerable impact on brain organization, memory ability

If mice lose their vision immediately after birth due to a genetic defect, this has a considerable impact, both on the organization of the cerebral cortex and on memory ability.

19 Dec 2018