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Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

Mesoblast Limited today announced that it has entered into a partnership with Cartherics Pty Ltd to develop allogeneic ‘off-the-shelf’ CAR-T cells armed with multiple targeting receptors for use in solid cancers. Off the shelf CAR-T therapies have the potential to reduce costs dramatically and open up this very effective treatment to millions of cancer patients across the world.

31 May 2018

Scientists introduce combination approach to fight cancer

For efficient cancer therapy with few side effects, the active drug should selectively attain high concentration in the tumor. In the journal Angewandte Chemie, scientists have introduced a new approach, in which two synergistic drug components are combined into a dimer.

31 May 2018

UTSA scientists explore stuttering and develop new technology to optimize brain function

A team of researchers at The University of Texas at San Antonio received a two-year, $387,000 grant, from the National Institutes of Health (NIH), to develop technology that will identify brain activity patterns that contribute to stuttering and use that technology to train people how to optimize brain functions.

31 May 2018

Telemedicine approach improves genetic counseling at community-based cancer care

Genetic counseling for cancer patients has become standard of care at academic medical centers, but patients cared for at community-based medical practices across the United States may not have access to these resources. Video and phone sessions can close that gap and bring genetic counseling to patients who would not otherwise have the chance to receive it, according to a new study from the Basser Center for BRCA at the University of Pennsylvania's Abramson Cancer Center.

31 May 2018

NIH study unravels how tularemia bacteria trick host cells to cause disease

Scientists from the National Institute of Allergy and Infectious Diseases--part of the National Institutes of Health--have unraveled the process by which the bacteria cause disease.

31 May 2018

Researchers identify workplace dress codes as hindrance for people with disabilities

According to the U.S. Census, nearly 20 million people of working age live with a disability. While past research has indicated that people living with disabilities face barriers in workplace participation, researchers from the University of Missouri have now found one hindrance to workplace participation for people with disabilities is the lack of appropriate clothing. This barrier increases their stigma and decreases their confidence.

31 May 2018

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Like exposing a crime boss whose authority has gone undetected, St. Jude Children's Research Hospital scientists have identified a hidden driver that influences production of the T cells that fight cancer and infections. The study appears today as an advance online publication in the journal Nature.

31 May 2018

New guideline for HER2 testing in breast cancer benefits patients and clinicians

Published today, a Focused Update to the American Society of Clinical Oncology/College of American Pathologists guideline for human epidermal growth factor receptor 2 (HER2) testing in breast cancer brings new levels of clarity that will benefit patients and clinical teams alike.

31 May 2018

FDA approves first stand-alone prosthetic iris in the U.S.

The U.S. Food and Drug Administration today approved the first stand-alone prosthetic iris in the United States, a surgically implanted device to treat adults and children whose iris (the colored part of the eye around the pupil) is completely missing or damaged due to a congenital condition called aniridia or other damage to the eye.

30 May 2018

Review: Health information exchanges reduce costs and lead to better care

An updated systematic review of recent studies of health information exchanges found evidence the exchanges reduced both the cost of health care and its use. That contrasts with an assessment published three years ago that found little such evidence.

30 May 2018

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

The U.S. Food and Drug Administration today expanded the approval of Xeljanz (tofacitinib) to include adults with moderately to severely active ulcerative colitis. Xeljanz is the first oral medication approved for chronic use in this indication.

30 May 2018

Novel surgical approach to limb amputation improves sensation, control of prosthesis

Humans can accurately sense the position, speed and torque of their limbs, even with their eyes shut. This sense, known as proprioception, allows humans to precisely control their body movements.

30 May 2018

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

Our immune system's arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system.

30 May 2018

Impaired maternal-fetal environment associated with lower survival after surgery in newborns with CHD

Children who undergo surgery for congenital heart disease have lower survival rates by three years of age if there are specific problems during fetal development, such as hypertension in the mother or the newborn being born preterm or small for gestational age.

30 May 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

Zinc and copper metabolism in baby teeth may help predict ASD risk

Using evidence found in baby teeth, researchers from the Department of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai report that cycles involved in zinc and copper metabolism are dysregulated in autism spectrum disorder, and can be used to predict who will later develop the disease.

30 May 2018

Research supports use of symbolic gestures to foster child's verbal growth and language skills

Many parents are hesitant to use signs with their babies because they fear it will delay their child's verbal growth. However, research supports the use of symbolic gestures to foster language skills and verbal development.

30 May 2018

New trial to test if omega-3 capsules can stop secondary liver cancer recurrence after surgery

A new clinical trial from the University of Leeds is testing omega-3 capsules in patients who have bowel cancer which has spread to the liver, to see if it can stop the cancer returning after surgery.

30 May 2018

Abortion does not increase woman's risk for depression

Having an abortion does not increase a woman's risk for depression, according to a new study of nearly 400,000 women published today in JAMA Psychiatry.

30 May 2018

Cockroach milk may sound yucky but could be the next big 'superfood'

According to a new report, cockroach milk could be the next big superfood as it is packed with nutrients over and above conventional dairy as well as almond and soy milk preparations. The results of the study appeared in the latest issue of the Journal of the International Union of Crystallography.

30 May 2018

Medical News

Mesoblast and Cartherics form partnership to develop 'off-the-shelf' CAR-T therapies for solid cancers

Scientists introduce combination approach to fight cancer

UTSA scientists explore stuttering and develop new technology to optimize brain function

Telemedicine approach improves genetic counseling at community-based cancer care

NIH study unravels how tularemia bacteria trick host cells to cause disease

Researchers identify workplace dress codes as hindrance for people with disabilities

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

New guideline for HER2 testing in breast cancer benefits patients and clinicians

FDA approves first stand-alone prosthetic iris in the U.S.

Review: Health information exchanges reduce costs and lead to better care

FDA approves first oral medication for adults with moderately to severely active ulcerative colitis

Novel surgical approach to limb amputation improves sensation, control of prosthesis

Scientists engineer bi-specific antibodies that attract immune killers directly to cancer cells

Impaired maternal-fetal environment associated with lower survival after surgery in newborns with CHD

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

Zinc and copper metabolism in baby teeth may help predict ASD risk

Research supports use of symbolic gestures to foster child's verbal growth and language skills

New trial to test if omega-3 capsules can stop secondary liver cancer recurrence after surgery

Abortion does not increase woman's risk for depression

Cockroach milk may sound yucky but could be the next big 'superfood'

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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