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Study reveals why Alzheimer's drugs fail in clinical trials

A tremendous amount of Amyloid-β peptide (Aβ) (a peptide of ～40 amino acids) accumulates in the brain of Alzheimer's disease patients. γ-Secretase inhibitors were designed to inhibit the enzymatic activity that produces Aβ. By reducing Aβ production, γ-secretase inhibitors were considered able to treat Alzheimer's disease (Aβ hypothesis).

25 Oct 2017

Long-term risk of premature death in men and women strongly associated with depression, study reveals

A Stirling County study, published in Canadian Medical Association Journal, suggests that depression remains strongly associated with a higher risk of early death in both men and women.

25 Oct 2017

Scientists develop new method for enhancing breast reconstruction with autologous fat

5.000 women develop breast cancer every year in Austria. Surgical removal of the tumour continues to be a crucial part of successful treatment but frequently results in loss of breast tissue, making partial mastectomy necessary in 80% of cases.

25 Oct 2017

New trial to assess effectiveness of self-management program for women with pelvic organ prolapse

A new £1.1million trial led by the University of Stirling will assess whether a self-management program could help to improve the lives of women who suffer pelvic organ prolapse.

25 Oct 2017

Researchers discover mechanism that corrects protein misfolding in plants

Various human nervous system diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer's, Huntington's, and Parkinson's diseases, are associated with the same basic disorder: the loss of nerve cells capacity to fold their proteins correctly, which causes protein aggregations that form "clumps" that end up generating the cell death.

25 Oct 2017

New discovery could speed development and approval of antiviral drugs

New research shows that a new class of antiviral drugs works by causing the virus' replication machinery to pause and backtrack, preventing the virus from efficiently replicating. This discovery, made possible by a high-throughput experimental technique called "magnetic tweezers," could speed the development and approval of related antiviral drugs.

25 Oct 2017

Hospitals need to improve emergency care practices for treating older cancer patients, study reveals

A new study finds that patients with cancer, especially those aged 75 or older, are more likely to be admitted to the hospital – and less likely to be observed and released home – than patients without cancer.

25 Oct 2017

New survey finds huge decline in substance abuse, delinquency among teens

More than a decade of data indicates teens have become far less likely to abuse alcohol, nicotine and illicit drugs, and they also are less likely to engage in delinquent behaviors, such as fighting and stealing, according to results of a national survey analyzed by researchers at Washington University School of Medicine in St. Louis.

25 Oct 2017

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New research from The University of Texas Health Science Center at San Antonio and U.S. Department of Veterans Affairs has identified the molecular mechanism that causes kidney cancer to resist drug treatment.

25 Oct 2017

Proton beam therapy can help improve outcomes in elderly patients with esophageal cancer

A study led by Mayo Clinic researchers has found that proton beam therapy, in combination with chemotherapy, prior to surgery, may be a better option than a combination using traditional radiation therapy techniques with chemotherapy when treating elderly patients with esophageal cancer.

25 Oct 2017

Scientists get one step closer to reversing retinal degenerative diseases

Degenerative disorders affecting the retinal pigment epithelium (RPE), such as age-related macular degeneration and autosomal recessive bestrophinopathy, can ultimately lead to blindness. Some of these life-changing disorders are the result of mutations in a single gene, called BEST1.

25 Oct 2017

Researchers mine blood-based epigenetic data to gain insights into autism biology

Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.

25 Oct 2017

New set of guidelines released for managing and caring patients with mitochondrial disease

Physicians who see patients with mitochondrial disease now have a practical new tool--a set of guidelines for managing and caring for those patients.

25 Oct 2017

Weight loss following bariatric operation leads to improvements in heart health

In overweight and obese people, fat often gets deposited in the midsection of the body. Large amounts of this belly fat can lead to unhealthy changes in a heart's function and size.

25 Oct 2017

New York bans vaping, e-cigs from everywhere that smoking is

Governor of New York Andrew M. Cuomo has signed a legislation that prohibits electronic cigarette smoking in areas and regions where smoking tobacco products are banned. This is an addition to the Clean Indoor Air Act. This bill - S.2543A/ A.516A, is meant to prevent the exposure to the harmful chemicals from the e-cigarettes to people around these smokers.

24 Oct 2017

Stony Brook University scientist receives $3.9 million NIH grant for ALS research

Stony Brook University scientist Josh Dubnau, PhD, has received a $3.9 million grant from the National Institutes of Health to investigate the impact of environmental stressors and other external factors that contribute to the development of amyotrophic lateral sclerosis (ALS).

24 Oct 2017

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Genetically modified leaner pigs are on the cards soon. Researchers in china used the gene-editing technology, CRISPR, to create pigs that are less fatty and leaner with more muscle. This could mean genetically modified bacon on the plates.

24 Oct 2017

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

The genome editing tool known as CRISPR/Cas9 has opened many doors for biomedical research by allowing scientists to precisely edit DNA sequences and alter function. The technology offers hope for correcting genetic defects and preventing disease.

24 Oct 2017

Case report of a 21 year old woman sweating blood

She had a rare condition called hematohidrosis where she was sweating blood and her tears too contained blood. The dermatologists published the report of her rare case while protecting her identity, this week in the Canadian Medical Association Journal.

24 Oct 2017

Human exposure to glyphosate has increased significantly over 23 years, research finds

Analyzing samples from a prospective study, University of California San Diego School of Medicine researchers found that human exposure to glyphosate, a chemical widely found in weed killers, has increased approximately 500 percent since the introduction of genetically modified crops.

24 Oct 2017

Medical News

Study reveals why Alzheimer's drugs fail in clinical trials

Long-term risk of premature death in men and women strongly associated with depression, study reveals

Scientists develop new method for enhancing breast reconstruction with autologous fat

New trial to assess effectiveness of self-management program for women with pelvic organ prolapse

Researchers discover mechanism that corrects protein misfolding in plants

New discovery could speed development and approval of antiviral drugs

Hospitals need to improve emergency care practices for treating older cancer patients, study reveals

New survey finds huge decline in substance abuse, delinquency among teens

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

Proton beam therapy can help improve outcomes in elderly patients with esophageal cancer

Scientists get one step closer to reversing retinal degenerative diseases

Researchers mine blood-based epigenetic data to gain insights into autism biology

New set of guidelines released for managing and caring patients with mitochondrial disease

Weight loss following bariatric operation leads to improvements in heart health

New York bans vaping, e-cigs from everywhere that smoking is

Stony Brook University scientist receives $3.9 million NIH grant for ALS research

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

Case report of a 21 year old woman sweating blood

Human exposure to glyphosate has increased significantly over 23 years, research finds

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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