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People with severe mental illness have higher risk for cardiovascular disease, study reveals

An international study of more than 3.2 million people with severe mental illness reveals a substantially increased risk for developing cardiovascular disease compared to the general population.

12 May 2017

Scientists use new RNA sequencing and statistical techniques to track stem cells in the nose

Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.

12 May 2017

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

The discovery of key signals that help tissues repair after injury could pave the way for new treatments for asthma and organ scarring, a study suggests.

12 May 2017

Women tend to endorse gender roles portrayed on TV at expense of their needs, says researcher

College women who frequently watch television or who believe that the content is real, tend to endorse the gender roles that are portrayed often on TV, says a University of Michigan researcher.

11 May 2017

Phase 1 trial shows safety and tolerability of oncolytic HSV-1 for children, young adults with cancer

HSV1716 – an oncolytic herpes simplex virus-1 – has been studied in adults via injection into the brain and superficial tumors.

11 May 2017

Research findings identify protein as potential new drug target for HCMV infections

Scientists have demonstrated that a human protein known as valosin containing protein (VCP) is essential for replication of human cytomegalovirus. The findings, published in PLOS Pathogens, identify VCP as a potential new treatment target.

11 May 2017

Study finds substantial increase in hepatitis C infections among pregnant women

Hepatitis C infections among pregnant women nearly doubled from 2009-2014, likely a consequence of the country's increasing opioid epidemic that is disproportionately affecting rural areas of states including Tennessee and West Virginia.

11 May 2017

Scientists reveal how immune cells activate to kill parasitic worms

An international team of researchers including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine, reveals how immune cells called macrophages activate to kill parasitic worms.

11 May 2017

New study reveals 80% of stethoscopes are contaminated with infectious bacteria

There are now two reasons for patients to flinch at the touch of a stethoscope: because it's cold, of course; and because it's covered with germs.

11 May 2017

Preclinical data reinforces potential efficacy, durability of investigational gene therapy for DMD

Solid Biosciences announced today that new data from two preclinical studies reinforce the potential of its investigational microdystrophin gene therapy, SGT-001, to be an effective treatment approach for Duchenne muscular dystrophy.

11 May 2017

Study reveals how proline metabolism supports breast cancer metastasis

A multinational group of scientists, led by professor Sarah-Maria Fendt, have discovered that breast cancer cells that have invaded other organs rely on a different nutrient metabolism to produce energy than normal cells and non-metastasizing cancer cells.

11 May 2017

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechanism that links the two phenomena.

11 May 2017

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

According to research published online in The FASEB Journal, scientists have discovered a dual peptide called "PGLP-1" that promotes insulin secretion and inhibits gluconeogenesis.

11 May 2017

Scientists shed light on evolutionary history of multidrug-resistant enterococci bacteria

Enterococci bacteria are the bane of hospitals, causing thousands of multidrug-resistant infections in patients each year.

11 May 2017

CUMC researchers create new organoids that mimic features of full-sized lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung- have been created from human pluripotent stem cells by researchers at Columbia University Medical Center. The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

11 May 2017

Improper methylation of cilia protein linked to increased risk of neural tube defects

Research published online in The FASEB Journal shows that the improper methylation of a protein called "Septin2," which regulates the structure of cilia, was associated with an increased risk of having a neural tube defect (NTD) and confirms that cilia are important factors in determining susceptibility of NTDs.

11 May 2017

Medical News

People with severe mental illness have higher risk for cardiovascular disease, study reveals

Scientists use new RNA sequencing and statistical techniques to track stem cells in the nose

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

Women tend to endorse gender roles portrayed on TV at expense of their needs, says researcher

Phase 1 trial shows safety and tolerability of oncolytic HSV-1 for children, young adults with cancer

Research findings identify protein as potential new drug target for HCMV infections

Study finds substantial increase in hepatitis C infections among pregnant women

Scientists reveal how immune cells activate to kill parasitic worms

New study reveals 80% of stethoscopes are contaminated with infectious bacteria

Preclinical data reinforces potential efficacy, durability of investigational gene therapy for DMD

Study reveals how proline metabolism supports breast cancer metastasis

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

Researchers discover dual-functional compound that shows potential to combat type 1, type 2 diabetes

Scientists shed light on evolutionary history of multidrug-resistant enterococci bacteria

CUMC researchers create new organoids that mimic features of full-sized lung

Improper methylation of cilia protein linked to increased risk of neural tube defects

Study shows link between susceptibility to malignant hyperthermia and exertional heat stroke

Suppression of thyroid hormone receptor protects cone cells in mouse models of retinal diseases

Research explores effect of alcohol on adolescent brain

Researchers identify microRNA biomarker linked to incidence of atrial fibrillation

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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