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$Lipoprotein apheresis may have new role in patients with refractory angina$

Lipoprotein apheresis may have new role in patients with refractory angina

Initial investigation of patients with suspected coronary heart disease (CHD) using functional imaging - rather than guideline-directed care - resulted in significantly less unnecessary angiography, according to results of the CE-MARC 2 trial.

29 Aug 2016

PACIFIC study may offer guidance to choose from number of non-invasive coronary artery imaging

For patients presenting for the first time with suspected coronary artery disease (CAD) clinicians have had a number of non-invasive diagnostic tests to choose from, but little evidence for which is best.

29 Aug 2016

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

In patients with high-risk coronary artery disease (CAD), an active strategy of detecting and treating asymptomatic multisite artery disease (MSAD) combined with intensive medical therapy did not improve 2-year outcomes compared to a more traditional approach of managing only symptomatic coronary and extracoronary lesions, new research shows.

29 Aug 2016

Invasive imaging technique can help achieve better outcomes in patients undergoing PCI

An invasive imaging technique called optical coherence tomography (OCT) can visualize the coronary arteries in patients undergoing percutaneous coronary intervention (PCI) and lead to better outcomes compared to standard angiography-guided PCI, according to new findings reported here.

29 Aug 2016

New study shows how the brain calculates distribution of probabilities in orbitofrontal cortex

Even if we find it difficult to calculate complicated probabilities on the spot, our brains constantly carry out these sorts of computations without our awareness -- and they're remarkably good at it.

29 Aug 2016

Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

For heart failure patients with cardiac implantable electronic devices (CIEDs), remote monitoring of their condition does not improve outcomes compared to usual care, according to Hot Line results presented at ESC Congress 2016 and to be simultaneously published in JAMA.

29 Aug 2016

Long-term exposure to combination of lower LDL-C and SBP can reduce cardiovascular risk

Long-term exposure to the combination of even modestly lower LDL cholesterol (LDL-C) and systolic blood pressure (SBP) has the potential to "dramatically reduce" a person's lifetime risk of cardiovascular disease, according to new findings reported at ESC Congress 2016.

29 Aug 2016

HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

Survival and other cardiovascular outcomes were not significantly reduced with intensive treatment using a second-line cholesterol-lowering medication on top of a standard statin, compared to statin treatment alone in patients with acute coronary syndrome (ACS) and dyslipidemia, investigators reported here.

29 Aug 2016

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

A single dose of mesenchymal stem cells delivered intravenously to patients with chronic non-ischemic cardiomyopathy was not associated with significant cardiac structural or functional improvements, but did result in several clinically relevant benefits, according to results from a phase II-a randomized trial.

29 Aug 2016

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

BRAF mutation occurs in between 40% and 50% of metastasising melanomas (skin cancers), boosting tumour growth.

29 Aug 2016

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Patients who have heterozygous familial hypercholesterolemia (HeFH), a condition that causes abnormally raised low-density lipoprotein cholesterol (LDL-C) levels and premature cardiovascular disease, can significantly reduce or even eliminate their need for expensive and time-consuming apheresis treatments with the PCSK9 inhibitor alirocumab.

29 Aug 2016

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

A therapy that uses bone-marrow stem cells to promote heart repair did not significantly improve the primary outcome over a sham procedure among patients with congestive heart failure.

29 Aug 2016

An Introduction to Specialty Pharmaceuticals

In this interview, News Medical talks to David Moran, Managing Director of Clinigen SP about specialty pharmaceuticals.

From Clinigen Group 29 Aug 2016

Cleft palate repair costs the same for internationally adopted children

Since 2009, United States residents have adopted more children from China than any other country. Since China has a high prevalence of cleft lip and palate, some of these children require extra medical care early in their lives. Many prospective families are fearful of the treatment costs needed by a child affected by cleft lip and palate. However, recent research suggests that the costs are not nearly as high as previously thought.

29 Aug 2016

Each NHS hospital admission linked to 2% increased risk of death for heart failure patients

Heart failure patients have a 2% increased risk of dying with each admission to NHS hospitals, according to research presented at ESC Congress 2016 today.

29 Aug 2016

Waiting impulsivity may help spot offspring of alcoholics at risk for developing alcohol addiction

Researchers know that youth with a family history of alcoholism have a greater risk of developing an alcohol use disorder; this heightened vulnerability may be due to impulsive behavior.

29 Aug 2016

Occasional medicine users not getting the full benefits of their medicines

Survey findings released for Be Medicinewise Week (22-28 August) have revealed that occasional users of medicines—including prescription, over-the-counter, and alternative or complementary forms of medicines—are potentially not getting the full benefits from their medicines, compared to people who take medicines more often.

29 Aug 2016

Cases of rotavirus infections fall by 84% thanks to vaccination

Figures published by Public Health England have shown that the number of diagnosed Rotavirus cases, a highly infectious virus which may cause vomiting and diarrhoea, have dropped by 84% since the introduction of a vaccine to the national childhood immunisation schedule in July 2013.

29 Aug 2016

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Although the current practice of analysing defined gene panels for a specific disease has great utility, it is of limited benefit when a condition is not well defined.

29 Aug 2016

Blacktrace launches Particle Works, a nano- and microstructure specialist brand

Blacktrace Holdings Limited, a leading group of companies focused on Productizing Science®, will be launching its latest brand, Particle Works, at the NANOTEXNOLOGY 2016 conference in Thessaloniki, Greece, from the 4th to the 8th of July. The Blacktrace group’s many years of expertise and world-leading capabilities in the design, development and manufacture of automated microfluidic continuous flow equipment provide the perfect foundation for this newly created brand specializing in high performance nano- and microstructured materials.

29 Aug 2016

Medical News

Lipoprotein apheresis may have new role in patients with refractory angina

PACIFIC study may offer guidance to choose from number of non-invasive coronary artery imaging

Active strategy of detecting and treating asymptomatic MSAD results in no clinical benefit

Invasive imaging technique can help achieve better outcomes in patients undergoing PCI

New study shows how the brain calculates distribution of probabilities in orbitofrontal cortex

Remote monitoring shows no improvement in outcomes for heart failure patients with CIEDs

Long-term exposure to combination of lower LDL-C and SBP can reduce cardiovascular risk

HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

Researcher identifies mechanisms that may cause resistance to BRAF inhibitor

PCSK9 inhibitor can reduce need for apheresis treatment in patients with familial hypercholesterolemia

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

An Introduction to Specialty Pharmaceuticals

Cleft palate repair costs the same for internationally adopted children

Each NHS hospital admission linked to 2% increased risk of death for heart failure patients

Waiting impulsivity may help spot offspring of alcoholics at risk for developing alcohol addiction

Occasional medicine users not getting the full benefits of their medicines

Cases of rotavirus infections fall by 84% thanks to vaccination

Is the virtual gene panel the way forward asks Congenica at Dx Summit

Blacktrace launches Particle Works, a nano- and microstructure specialist brand

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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