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Several medical groups urge Congress to provide required funding for Zika virus prevention, treatment

The American College of Physicians along with the American Academy of Family Physicians, the American Academy of Pediatrics and the American Congress of Obstetricians and Gynecologists sent a letter today to House and Senate leaders urging them to immediately pass legislation that would provide the highest possible funding level for research, prevention, control, and treatment of illnesses associated with the Zika virus that is commensurate with the public health emergency that the virus represents.

28 May 2016

Surrogate endpoints for cancer drug approval often lack formal empirical verification

Surrogate endpoints used to support the majority of new cancer drugs approved in the U.S. often lack formal study, according to the authors of a study published in the June issue of Mayo Clinic Proceedings.

28 May 2016

New research estimates unmet surgical needs of forcibly displaced persons

New research from the Johns Hopkins Bloomberg School of Public Health suggests that the world's estimated 60 million refugees, displaced from their homes due to conflict, persecution or human rights violations, may need at least 2.78 million surgeries a year, something thought to be very difficult to arrange in the midst of their upheaval.

28 May 2016

Rise and fall of alcohol-related mortality in Scotland linked to variations in alcohol affordability

New research has found that the rise in alcohol-related mortality during the 1990s and early 2000s in Scotland, and the subsequent decline, were likely to be explained in part by increasing then decreasing alcohol affordability.

28 May 2016

OIST scientists reveal how big protein complex inside E. coli cells divide and multiply

Escherichia coli (E. coli) are bacteria that live all around and inside of us. Most E. coli are harmless, but some strains can cause illness, and can even, in extreme cases, be deadly. With recent outbreaks of E. coli around the world, there is a fear of acquiring an infection from these bacteria.

28 May 2016

Slime mold provides key to understanding directional ability of immune cells

How white blood cells in our immune systems home in on and engulf bacterial invaders--like humans following the scent of oven-fresh pizza--has long been a mystery to scientists.

28 May 2016

Reducing use of opioid medications possible, but challenging

A team of researchers at the University of Colorado School of Medicine and the VA Eastern Colorado Health Care System recently surveyed patients to understand barriers to reducing the use of opioids to manage chronic pain. The results of those interviews are published in the current issue of the journal Pain Medicine.

28 May 2016

New, simpler way for encapsulation-free controlled protein release

A U of T Engineering team has designed a simpler way to keep therapeutic proteins where they are needed for long periods of time. The discovery is a potential game-changer for the treatment of chronic illnesses or injuries that often require multiple injections or daily pills.

28 May 2016

Inadequate monitoring places post-operative patients at risk for opioid-induced respiratory depression

Nearly 75 percent of hospitalized patients receiving opioids for pain management are not monitored according to hospital guidelines.

28 May 2016

Researchers demonstrate decisive role of cholesterol in T cell activation

T cell receptors are an important part of the human immune system. They are able to switch their conformation from an inactive to an active state spontaneously without any antigens present.

28 May 2016

Study finds link between respiratory sinus arrhythmia and survival prospects of heart attack patients

The heart rate may be an indicator of a person's life expectancy. A research team at the Technical University of Munich has to this end analyzed an effect which at first seems paradoxical: Minor irregularities in the heartbeat are indicative of a healthy body.

28 May 2016

$Review outlines fatigue, fracture behavior of wire-based systems used in biomedical applications$

Review outlines fatigue, fracture behavior of wire-based systems used in biomedical applications

Gbur and Lewandowski, of Case Western Reserve University, have published an extensive review of the fatigue and fracture behavior of wire-based systems used in biomedical applications in International Materials Reviews.

28 May 2016

Pharmacist suggests education as foremost strategy to control opioid abuse

Technologies that make it harder for people to abuse opioids - like doctoring pills so that they produce unpleasant side effects if broken, crushed or injected -- likely will have limited effectiveness in stemming the global epidemic of opioid abuse, according to Adam Kaye, a professor of pharmacy at University of the Pacific.

28 May 2016

New CRISPR-EZ method makes genome editing much easier in mice

University of California, Berkeley scientists have developed a quicker and more efficient method to alter the genes of mice with CRISPR-Cas9, simplifying a procedure growing in popularity because of the ease of using the new gene-editing tool.

28 May 2016

Study finds majority of older Americans work longer after retirement

Departing the workforce entirely and entering retirement at age 65 is no longer a reality for many older people in the United States, according to a recent survey by The Associated Press-NORC Center for Public Affairs Research.

28 May 2016

Overcoming barriers to move beyond race-based treatment decisions

Prescribing certain medications on the basis of a patient's race has long come under fire from those uneasy with using race as a surrogate for biology when treating disease.

28 May 2016

NASA releases new video that highlights Mark and Scott Kelly's metabolites

NASA's Human Research Program is releasing "Metabolomics: You Are What You Eat" video to highlight its Twins Study which uses omics to study Mark and Scott Kelly's metabolites.

28 May 2016

Certain HLA genes may increase ovarian cancer risk in women

Researchers in the Center for Immunotherapy at Roswell Park Cancer Institute have evaluated the human leukocyte antigen (HLA), a group of genes that help regulate the body's immune system, for underlying differences in ovarian cancer patients' response to therapy.

28 May 2016

Vismodegib drug shows no addded benefit in advanced or symptomatic metastatic BCC patients

Vismodegib (trade name: Erivedge) has already been approved since 2013 for the treatment of patients with locally advanced basal cell carcinoma (BCC) or symptomatic metastatic BCC and has already undergone an early benefit assessment according to the Act on the Reform of the Market for Medicinal Products.

28 May 2016

New player in calcium signalling pathways acts as molecular brake to Orai activation

Information flow in cells relies on calcium as a key agent in several signalling pathways. Calcium dependent signalling is crucial in nearly every aspect of life - muscle movement, immune reactions, nerve function, light sensing and many such processes.

28 May 2016

Medical News

Several medical groups urge Congress to provide required funding for Zika virus prevention, treatment

Surrogate endpoints for cancer drug approval often lack formal empirical verification

New research estimates unmet surgical needs of forcibly displaced persons

Rise and fall of alcohol-related mortality in Scotland linked to variations in alcohol affordability

OIST scientists reveal how big protein complex inside E. coli cells divide and multiply

Slime mold provides key to understanding directional ability of immune cells

Reducing use of opioid medications possible, but challenging

New, simpler way for encapsulation-free controlled protein release

Inadequate monitoring places post-operative patients at risk for opioid-induced respiratory depression

Researchers demonstrate decisive role of cholesterol in T cell activation

Study finds link between respiratory sinus arrhythmia and survival prospects of heart attack patients

Review outlines fatigue, fracture behavior of wire-based systems used in biomedical applications

Pharmacist suggests education as foremost strategy to control opioid abuse

New CRISPR-EZ method makes genome editing much easier in mice

Study finds majority of older Americans work longer after retirement

Overcoming barriers to move beyond race-based treatment decisions

NASA releases new video that highlights Mark and Scott Kelly's metabolites

Certain HLA genes may increase ovarian cancer risk in women

Vismodegib drug shows no addded benefit in advanced or symptomatic metastatic BCC patients

New player in calcium signalling pathways acts as molecular brake to Orai activation

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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