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Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs

For more than a decade, biomedical researchers have been looking for better ways to deliver cancer-killing medication directly to tumors in the body. Tiny capsules, called nanoparticles, are now being used to transport chemotherapy medicine through the bloodstream, to the doorstep of cancerous tumors.

11 Apr 2016

The Weizmann Institute of Science purchases novel Aeon™ 1GHz NMR system from Bruker

The Weizmann Institute of Science in Rehovot, Israel today announced major scientific instrument purchases from Bruker (NASDAQ: BRKR), including a novel Aeon™ 1GHz nuclear magnetic resonance (NMR) system for expanding frontiers in structural biology and intrinsically disordered protein (IDPs) research. Furthermore, the Weizmann Institute is adding an Aeon 600 MHz NMR, a 263 GHz dynamic nuclear polarization (DNP)-NMR system, and a Biospec® 15 Tesla system for preclinical ultra-high field magnetic resonance imaging (MRI). Various NMR and electron paramagnetic resonance (EPR) instrument upgrades round out this major acquisition, instantly propelling the Weizmann Institute to the frontiers of modern magnetic resonance research infrastructure.

From Bruker BioSpin Division 11 Apr 2016

Cyclodextrin dissolves cholesterol crystals, reduces atherosclerotic plaques

Cardiovascular disease from atherosclerosis is one of the most common causes of death worldwide. Inflammation plays a crucial role in atherosclerosis and cholesterol crystals are considered to be early triggers in the development of the disease.

11 Apr 2016

New GHz-class NMR magnet and probe technologies introduced by Bruker at ENC 2016

At the 57th Experimental Nuclear Magnetic Resonance Conference (www.enc-conference.org), Bruker announced new GHz-class NMR magnet and probe technologies to enable expanding frontiers in structural biology, membrane protein and intrinsically disordered protein (IDP) research.

From Bruker BioSpin Division 11 Apr 2016

Study reveals new activation mechanism for protein kinases

Protein kinases, most scientists would agree, regulate nearly every aspect of cell life. It is no surprise, then, that having faulty protein kinases may lead to a number of human conditions, including cardiovascular diseases, cancer and diabetes.

11 Apr 2016

Researchers identify influenza D antibodies in small ruminants

Although a new influenza virus, now called influenza D, was discovered first in pigs, researchers found it was more common in cattle. However, further research has identified antibodies to the virus in small ruminants, but not in poultry.

11 Apr 2016

Study finds how tumour cells grow through scavenging bad cholesterol

Several studies have recognized a link between obesity and cancer. Richard Lehner, professor of Pediatrics and investigator at the University of Alberta's Faculty of Medicine & Dentistry, has taken his research further to understand how tumour cells grow through scavenging very low-density lipoproteins (VLDL) and low-density lipoproteins (LDL), commonly known as the "bad cholesterol", and what mechanisms can be used to reduce the malignant cells' growth.

11 Apr 2016

Added benefit of crizotinib drug for first-line treatment of advanced bronchial carcinoma not proven

The drug crizotinib (trade name: Xalkori) has been available since 2012 for patients with advanced non-small cell lung cancer (bronchial carcinoma) who have a high activity of the enzyme anaplastic lymphoma kinase (ALK) and have already received another treatment. In November 2015, the approval was extended to first-line treatment.

11 Apr 2016

Long-term medication use reduces risk of relapse and improves symptoms in BDD patients

People with Body Dysmorphic Disorder (BDD) fare better and are less likely to relapse when treated with medication on a long-term basis, according to researchers at Rhode Island Hospital and Massachusetts General Hospital.

11 Apr 2016

Researchers identify gene crucial to development of coeliac disease

Coeliac disease is a chronic, immunological disease that is manifested as intolerance to gluten proteins present in wheat, rye and barley. This intolerance leads to an inflammatory reaction in the small intestine that hampers the absorption of nutrients. The only treatment is a strict, life-long, gluten-free diet.

11 Apr 2016

Simple blood test rapidly detects key genetic mutations in non-small cell lung tumors

A simple blood test can rapidly and accurately detect mutations in two key genes in non-small cell lung tumors, researchers at Dana-Farber Cancer Institute and other institutions report in a new study - demonstrating the test's potential as a clinical tool for identifying patients who can benefit from drugs targeting those mutations.

11 Apr 2016

Rockefeller scientists study molecular mechanism that causes linker cell death in worms

Some cells are meant to live, and some are meant to die. The linker cell of Caenorhabditis elegans, a tiny worm that is a favored model organism for biologists, is among those destined for termination.

11 Apr 2016

AstraZeneca, MedImmune to present new clinical trial and scientific data on lung cancer treatments at ELCC 2016

AstraZeneca and its global biologics research and development arm, MedImmune, will report new clinical trial and scientific data from their industry-leading lung cancer franchise of marketed and pipeline medicines at the European Lung Cancer Conference in Geneva, Switzerland, 13 -16 April 2016.

11 Apr 2016

Orthopedic wear and mechanical testing webinar to be hosted by Lucideon

Lucideon, the international materials technology company, together with Knight Mechanical Testing, is hosting a webinar entitled ‘Wear and Mechanical Testing of Hips and Knees - What the Standards Don’t Tell You’ on the 28th April at 3PM (UK time) 10AM (EST).

From Lucideon 8 Apr 2016

How can deep learning impact healthcare?

“Genomic medicine really needs deep learning,” these were the words of keynote speaker Brendan Frey, CEO Deep Genomics at RE-WORK’s Deep Learning in Healthcare Summit 2016.

8 Apr 2016

Keynotes announced for ECCMID 2016

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) previews some of the keynote lectures at the 26th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). The globe’s most prominent infection specialists will be gathering at its annual congress in Amsterdam from 9 – 12 April 2016.

8 Apr 2016

Obesity and diabetes during pregnancy can cause excessive growth of foetus

A recent study conducted by researchers at the University of Cambridge showed that obese women who develop gestational diabetes have a five-fold greater risk of excessive foetal growth at 6 months gestation. Furthermore, it revealed that such excessive growth starts before women are screened for gestational diabetes.

8 Apr 2016

Medical News

Novel nanoparticle drug delivery system for enhanced tumor penetration of cancer drugs

The Weizmann Institute of Science purchases novel Aeon™ 1GHz NMR system from Bruker

Cyclodextrin dissolves cholesterol crystals, reduces atherosclerotic plaques

New GHz-class NMR magnet and probe technologies introduced by Bruker at ENC 2016

Study reveals new activation mechanism for protein kinases

Researchers identify influenza D antibodies in small ruminants

Study finds how tumour cells grow through scavenging bad cholesterol

Added benefit of crizotinib drug for first-line treatment of advanced bronchial carcinoma not proven

Long-term medication use reduces risk of relapse and improves symptoms in BDD patients

Researchers identify gene crucial to development of coeliac disease

Simple blood test rapidly detects key genetic mutations in non-small cell lung tumors

Rockefeller scientists study molecular mechanism that causes linker cell death in worms

AstraZeneca, MedImmune to present new clinical trial and scientific data on lung cancer treatments at ELCC 2016

Orthopedic wear and mechanical testing webinar to be hosted by Lucideon

How can deep learning impact healthcare?

Keynotes announced for ECCMID 2016

Obesity and diabetes during pregnancy can cause excessive growth of foetus

Proposed charging of migrants for use of the NHS is against government principles

Rituximab shows second-line promise in autoimmune limbic encephalitis

Epilepsy drug exposure does not increase newborn orofacial cleft risk

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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