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Brominated fire retardants overstimulate aldosterone in a way that may lead to cardiovascular disease

Brominated fire retardants, used in many consumer products and known to cause hormonal irregularities, overstimulates an adrenal gland hormone in a way that may lead to the development of cardiovascular disease, new research in human cells finds. Researchers will present their study results Saturday at the Endocrine Society's 98th annual meeting in Boston.

4 Apr 2016

Cambridge Pharmaceutical Cryo-EM Consortium formed by FEI, five pharmaceutical companies, the Medical Research Council and the University of Cambridge

FEI (NASDAQ: FEIC) has partnered with five pharmaceutical companies: Astex Pharmaceuticals, AstraZeneca, GlaxoSmithKline, Heptares Therapeutics, and UCB; the Medical Research Council Laboratory of Molecular Biology (MRC-LMB); and the University of Cambridge’s Nanoscience Centre, to form the “Cambridge Pharmaceutical Cryo-EM Consortium,” which is the first of its kind worldwide.

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Apr 2016

Patient-oriented tool helps shared decision-making between patients and physicians for chest pain

Patients who arrive at the emergency department with low-risk chest pain and talk through treatment options with a physician show improved knowledge of their health status and follow-up options, compared with patients who received standard counseling from a physician, according to Mayo Clinic research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Deferred stent implantation fails to show benefit in STEMI patients

Delayed or deferred stent implantation in patients experiencing the deadliest form of heart attack--ST-segment elevation myocardial infarction (STEMI)—failed to reduce death from any cause, hospitalization for heart failure, subsequent heart attacks or the need for a repeat procedure to restore blood flow to the heart, researchers reported at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Frequent TAVR to replace damaged aortic heart valve improves patient outcomes

The more frequently a hospital performs a minimally invasive technique called transcatheter aortic valve replacement, or TAVR, to replace a damaged aortic heart valve, the better patients fare, on average, immediately after the procedure, researchers reported at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Cognitive speed of processing training could improve driving abilities of older drivers

Older drivers can see their driving abilities improve by participating in certain types of training that improves the brain's processing speed and how the mind reacts when attention is divided, according to a new study by a researcher from the University of South Florida and colleagues from several other universities.

4 Apr 2016

Apple body shape linked to higher heart risk than pear-shape in diabetics

People with type 1 or 2 diabetes who have apple-shaped bodies with excessive fat around the abdomen and stomach, can be at higher risk of serious heart disease than patients with pear-shaped figures who store excess fat around their hips, according to a new study from Intermountain Medical Center Heart Institute and John Hopkins University.

4 Apr 2016

Study demonstrates rarity of familial hypercholesterolemia mutations in individuals with high cholesterol

Only a small fraction of people with very high cholesterol can attribute their condition to a genetic mutation related to familial hypercholesterolemia, but individuals with these mutations face a high risk of developing early-onset coronary artery disease, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Technology-based virtual race helps participants lose weight, exercise more

A competition that used technology to encourage and track physical activity was effective at helping participants lose weight and exercise more in both developed and developing countries, according to a study presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Testosterone therapy helps reduce risk of adverse cardiovascular events in elderly men

A new multi-year study from the Intermountain Medical Center Heart Institute in Salt Lake City shows that testosterone therapy helped elderly men with low testosterone levels and pre-existing coronary artery disease reduce their risks of major adverse cardiovascular events — including strokes, heart attacks, and death.

4 Apr 2016

Women who undergo uterine fibroid embolization experience improved sexual function

Women who underwent a nonsurgical, image-guided treatment, uterine fibroid embolization (UFE), for the treatment of uterine fibroids experienced improved sexual function and a higher overall quality of life. The research, part of a French multicenter study, presented at the Society of Interventional Radiology's Annual Scientific Meeting, also found the vast majority of women treated with UFE sustained improvement for more than a year.

4 Apr 2016

Researchers compare lipid-lowering efficacy for two nonstatin therapies in statin-intolerant patients

Steven E. Nissen, M.D., of the Cleveland Clinic, and colleagues identified patients with muscle-related adverse effects from statins and compared lipid-lowering efficacy for two nonstatin therapies, ezetimibe and evolocumab. The study was published online by JAMA, and is being released to coincide with its presentation at the American College of Cardiology's 65th Annual Scientific Session & Expo.

4 Apr 2016

Liu Laboratory at Augusta University studies exosomes using Particle Metrix’s ZetaView

Particle Metrix, developers of versatile particle characterization solutions for the life sciences, report on the work in the Liu Laboratory at Augusta University which is studying exosomes where size and concentration are critical parameters.

4 Apr 2016

Investigational drug abaloparatide-SC may help increase bone mineral density in postmenopausal women

The investigational drug abaloparatide-SC (subcutaneous) may help increase bone mineral density in postmenopausal women and reduce their risk of fracture, new industry-sponsored research suggests. The results of the subgroup analysis within the ACTIVE clinical trial will be presented Friday, April 1, at ENDO 2016, the annual meeting of the Endocrine Society in Boston.

4 Apr 2016

Bariatric arterial embolization could offer viable, safe alternative to surgical weight-loss treatments

A safe, new, minimally invasive treatment, developed by interventional radiologists, led to sustained weight loss in severely obese people, according to research presented at the Society of Interventional Radiology's 2016 Annual Scientific Meeting. Researchers said the treatment--bariatric arterial embolization (BAE)--could offer individuals a viable, safe alternative to surgical weight-loss treatments.

4 Apr 2016

One in 10 people in UK believed to be vitamin B12 deficient

One in 10 people in the UK are believed to be deficient in vitamin B12 – that’s an astonishing six million people suffering from the consequences of having less than the optimum amount of B12 in their system.

From BetterYou Ltd 4 Apr 2016

Heart disease patients who experience mental stress ischemia tend to have higher levels of troponin

Some people with heart disease experience a restriction of blood flow to the heart in response to psychological stress. Usually silent (not painful), the temporary restriction in blood flow, called ischemia, is an indicator of greater mortality risk.

4 Apr 2016

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

Despite lowering low-density lipoprotein (LDL), known as "bad" cholesterol, while markedly increasing levels of high-density lipoprotein (HDL), or "good" cholesterol, a large clinical trial to investigate the cholesterol drug evacetrapib was discontinued early after a preliminary analysis showed it did not reduce rates of major adverse cardiovascular events, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Understanding idiopathic pulmonary fibrosis: an interview with Michael Durheim, M.D.

IPF is a rare and fatal lung disease that causes permanent scarring of the lungs, leading to debilitating shortness of breath and cough in affected patients. It affects as many as 132,000 Americans, most commonly those over the age of 65.

4 Apr 2016

Wear and medical device testing seminars to be run by Lucideon and STC in China

US and UK-based Lucideon, the materials technology company, and Hong Kong Standards and Testing Centre (STC), the testing, inspection and certification organization based in Hong Kong and China, are offering orthopaedic implant manufacturers in the Asia region, and their supply chain, a series of seminars on wear testing and medical devices testing.

From Lucideon 4 Apr 2016

Medical News

Brominated fire retardants overstimulate aldosterone in a way that may lead to cardiovascular disease

Cambridge Pharmaceutical Cryo-EM Consortium formed by FEI, five pharmaceutical companies, the Medical Research Council and the University of Cambridge

Patient-oriented tool helps shared decision-making between patients and physicians for chest pain

Deferred stent implantation fails to show benefit in STEMI patients

Frequent TAVR to replace damaged aortic heart valve improves patient outcomes

Cognitive speed of processing training could improve driving abilities of older drivers

Apple body shape linked to higher heart risk than pear-shape in diabetics

Study demonstrates rarity of familial hypercholesterolemia mutations in individuals with high cholesterol

Technology-based virtual race helps participants lose weight, exercise more

Testosterone therapy helps reduce risk of adverse cardiovascular events in elderly men

Women who undergo uterine fibroid embolization experience improved sexual function

Researchers compare lipid-lowering efficacy for two nonstatin therapies in statin-intolerant patients

Liu Laboratory at Augusta University studies exosomes using Particle Metrix’s ZetaView

Investigational drug abaloparatide-SC may help increase bone mineral density in postmenopausal women

Bariatric arterial embolization could offer viable, safe alternative to surgical weight-loss treatments

One in 10 people in UK believed to be vitamin B12 deficient

Heart disease patients who experience mental stress ischemia tend to have higher levels of troponin

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

Understanding idiopathic pulmonary fibrosis: an interview with Michael Durheim, M.D.

Wear and medical device testing seminars to be run by Lucideon and STC in China

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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