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Theravectys gets authorization to produce lentiviral vectors for clinical use and CAR-T cell-based immunotherapy

THERAVECTYS, a clinical development biotechnology company that focuses on the development of therapeutic vaccines and immunotherapies, proudly announces that its manufacturing plant has obtained the status of a pharmaceutical manufacturing establishment, granted by the French National Agency for Medicines and Health Products Safety.

26 Mar 2015

TSRI scientists identify enzyme that maintains healthy periods of inactivity in HSCs to prevent anemia

Stem cells can generate any type of cell in the body, but they are inactive most of the time—and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations. In the case of blood stem cells (also called hematopoietic stem cells or HSCs), this can lead to blood cancers, a loss of blood cells and an impaired ability to fight disease.

26 Mar 2015

Claritas to present data on Pediatric Neurological Exome Assay and new sequencing approach at ACMG 2015

Claritas Genomics will present data on the quality of parallel multi-technology sequencing, a comparison of the company’s phenotypically driven Pediatric Neurology Exome Assay to whole exome and panel-based approaches, three-part reports for rapid results reporting, and the clinical utility of the Neurology Exome’s tailored approach compared to other tests currently on the market.

26 Mar 2015

Denator partners with Maastricht University to develop sample stabilization approaches for clinical applications

Denator AB announced today that the company has entered into a 2-year collaboration with the Maastricht MultiModal Molecular Imaging Institute (M4I) of Maastricht University, the Netherlands. As part of the collaboration, Denator will work closely with the M4I Division of Imaging Mass Spectrometry, headed by university professor Ron Heeren, to jointly develop and evaluate innovative sample stabilization approaches for clinical applications.

26 Mar 2015

Limited anticancer role for preoperative statins in localised RCC setting

Statin use prior to undergoing nephrectomy is not associated with survival outcomes in patients with localised renal cell carcinoma, research suggests.

25 Mar 2015

IMDC prognostic model valid in second-line RCC therapy

The International Metastatic Renal Cell Carcinoma Database Consortium prognostic model can be applied to metastatic renal cell carcinoma patients receiving second-line targeted treatment, according to research published in The Lancet Oncology.

25 Mar 2015

Alternating sunitinib, everolimus not supported in advanced RCC

Australian researchers report that an alternating regimen of sunitinib and everolimus, although feasible and low-risk in patients with advanced renal cell carcinoma, failed to meet the prespecified criteria for use or continued development.

25 Mar 2015

HRQoL benefit of alternative sunitinib dosing schedule in RCC patients

Patients with metastatic renal cell carcinoma reported a marked improvement in their health-related quality of life when given sunitinib on a 2 weeks on and 1 week off schedule compared with a 4 weeks on and 2 weeks off regimen, a Japanese study finds.

25 Mar 2015

Angiotensin system inhibitor use improves metastatic RCC survival outcomes

Use of angiotensin system inhibitors is associated with significant survival benefits in metastatic renal cell carcinoma patients treated in the targeted therapy era, research findings indicate.

25 Mar 2015

Agena Bioscience releases LungFUSION Panel to identify gene fusions in NSCLC tumors

Agena Bioscience today released the LungFUSION Panel for rapid and sensitive identification of oncogenic ALK, RET, and ROS1 gene fusions in non-small cell lung cancer tumors.

25 Mar 2015

Regulus' RG-012 receives orphan medicinal product designation in EU for treatment of Alport syndrome

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today that the European Commission has granted orphan medicinal product designation for RG-012, a single stranded, chemically modified oligonucleotide that binds to and inhibits the function of microRNA-21 ("miR-21") for the treatment of Alport syndrome, a life-threatening genetic kidney disease with no approved therapy.

25 Mar 2015

Lycera achieves milestone in Merck research collaboration

Lycera Corp., a biopharmaceutical company developing breakthrough medicines to treat cancer and autoimmune disease, today announced the achievement of a milestone under the Company's collaboration agreement with Merck, known as MSD outside the United States and Canada, triggering an undisclosed payment.

25 Mar 2015

TVA Medical's novel hemodialysis access technique shows positive outcomes in clinical study

TVA Medical, Inc., today announced promising results from a clinical study evaluating a novel hemodialysis access technique that has the potential to revolutionize vascular access for patients with chronic kidney disease without the use of traditional open surgery.

25 Mar 2015

Accelovance named finalist for Best Contract Research Organization at ViE Awards

Accelovance, a therapeutically focused contract research organization (CRO), has been named a finalist for "Best Contract Research Organization" at the upcoming Vaccine Industry Excellence (ViE) Awards hosted by the World Vaccine Congress.

25 Mar 2015

POCP launches ePrescribing State Law Capsule in U.S.

Point-of-Care Partners, a leading health information technology (HIT) strategy and management consulting firm, has launched the ePrescribing State Law Capsule -- a recurring reference publication to simplify tracking of ePrescribing regulatory requirements in all 50 states and DC.

25 Mar 2015

APM, HIV/AIDS Resource Center merge to strengthen response to HIV in Southeast Michigan

In order to strengthen the response to HIV in Southeast Michigan, AIDS Partnership Michigan and HIV/AIDS Resource Center have merged their organizations. Building on a history of collaboration and excellence, the merger of APM and HARC will ensure the sustainability of comprehensive HIV/AIDS prevention and care in their now 10-county area where 63% of people living with HIV reside.

25 Mar 2015

FDA approves Quadracel vaccine to protect young children from life-threatening diseases

Sanofi Pasteur, the vaccines division of Sanofi, announced today that the U.S. Food and Drug Administration has approved use of Quadracel (Diphtheria and Tetanus Toxoids and Acellular Pertussis Absorbed and Inactivated Poliovirus; DTaP-IPV) vaccine for active immunization against diphtheria, tetanus, pertussis and poliomyelitis in children 4 through 6 years of age.

25 Mar 2015

Medical News

Theravectys gets authorization to produce lentiviral vectors for clinical use and CAR-T cell-based immunotherapy

TSRI scientists identify enzyme that maintains healthy periods of inactivity in HSCs to prevent anemia

Claritas to present data on Pediatric Neurological Exome Assay and new sequencing approach at ACMG 2015

Denator partners with Maastricht University to develop sample stabilization approaches for clinical applications

Limited anticancer role for preoperative statins in localised RCC setting

IMDC prognostic model valid in second-line RCC therapy

Alternating sunitinib, everolimus not supported in advanced RCC

HRQoL benefit of alternative sunitinib dosing schedule in RCC patients

Angiotensin system inhibitor use improves metastatic RCC survival outcomes

Agena Bioscience releases LungFUSION Panel to identify gene fusions in NSCLC tumors

Regulus' RG-012 receives orphan medicinal product designation in EU for treatment of Alport syndrome

Lycera achieves milestone in Merck research collaboration

TVA Medical's novel hemodialysis access technique shows positive outcomes in clinical study

Accelovance named finalist for Best Contract Research Organization at ViE Awards

POCP launches ePrescribing State Law Capsule in U.S.

APM, HIV/AIDS Resource Center merge to strengthen response to HIV in Southeast Michigan

FDA approves Quadracel vaccine to protect young children from life-threatening diseases

Pentax Medical announces new chief marketing officer and Americas region president

Vermillion announces total revenue of $1.6 million for fourth quarter 2014

National Science Foundation announces recipient of Faculty Early Career Development Award

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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