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ContraVir granted Type B meeting with FDA to discuss proposal for FV-100 Phase 3 trial

ContraVir Pharmaceuticals, Inc., a biopharmaceutical company focused on the development and commercialization of targeted antiviral therapies, announced today that it has been granted a Type B meeting with the U.S. Food and Drug Administration (FDA) to discuss its proposal for the design of a Phase 3 trial of ContraVir's lead antiviral candidate, FV-100.

7 Jan 2015

Certain patients with type 2 diabetes, renal impairment discouraged from taking metformin

Many patients with type 2 diabetes in the United States may be discouraged from taking metformin—a proven, oral diabetes medicine—because the U.S. Food and Drug Administration inappropriately labels the drug unsafe for some patients also suffering from kidney problems, researchers from Penn Medicine and Weill Cornel Medical College report this week in a research letter published in JAMA Internal Medicine.

7 Jan 2015

McGill University researchers identify network of complex neurons in the brain

Our ability to pay attention to certain things while ignoring distractions determines how good we are at a given task, whether it is driving a car or doing brain surgery. A research team at McGill University has for the first time convincingly identified a network of neurons in a particular area of the brain, the lateral prefrontal cortex, that interact with one another to promptly filter visual information while at the same time ignoring distractions. It's a discovery with potentially far reaching implications for people who suffer from diseases such as autism, ADHD and schizophrenia.

7 Jan 2015

Researchers detect close functional link between two brain regions for 'absolute pitch'

People who have "absolute pitch" can identify notes immediately without relying on a reference tone. Intensive research is being conducted into the neuronal basis of this extraordinary ability at the University of Zurich's Department of Neuropsychology. The researchers have now detected a close functional link between the auditory cortex in the brain and the frontal lobe in these extraordinary people - a discovery that is not only important in theory, but also in practice.

7 Jan 2015

Study: Almost 40% of people with abnormal results ignore bowel cancer screening tests

Almost 40 per cent of people who have abnormal results from bowel cancer screening tests and are referred for further investigation ignore their next screening invitation two years later, according to a Cancer Research UK study published today (Tuesday) in the British Journal of Cancer.

7 Jan 2015

More insight into influence of obesity on distribution, elimination of drugs needed, say experts

Doctors and pharmacists often do not take obesity into account when prescribing medication. For this, more insight into the influence of obesity on the distribution and elimination of drugs is of the utmost importance. This is emphasized by Catherijne Knibbe in the most recent issue of the Annual Review of Pharmacology and Toxicology.

7 Jan 2015

Arcturus to exhibit new mRNA therapeutics pipeline at two healthcare conferences

Arcturus Therapeutics Inc., developing the 'next wave' of RNA medicines, today announced that Joseph Payne, President and Chief Executive Officer, is scheduled to present a corporate overview, including the company's new messenger RNA (mRNA) therapeutics pipeline, at two upcoming healthcare conferences.

7 Jan 2015

Everyday actions could help prevent spread of flu among college students

As local college students return to Philadelphia from their long winter breaks over the next several days, it is likely that they'll be bringing who-knows-what germs with them from home, said Stacey A. Gorski, PhD, a biology professor who specializes in immunology at University of the Sciences in Philadelphia.

7 Jan 2015

Researchers examine ischemic complications in patients who receive flow-diverting stents

The use of flow-diverting stents to treat intracranial aneurysms appears safe and highly successful. Recently, however, there have been reports of ischemic complications occurring in brain territories supplied by the parent artery in which the stent is placed and in brain regions fed by small arterial branches whose ostia are covered by the stent.

7 Jan 2015

Novel drug delivery technique uses graphene to deliver two anticancer drugs sequentially to cancer cells

An international team of researchers has developed a drug delivery technique that utilizes graphene strips as "flying carpets" to deliver two anticancer drugs sequentially to cancer cells, with each drug targeting the distinct part of the cell where it will be most effective. The technique was found to perform better than either drug in isolation when tested in a mouse model targeting a human lung cancer tumor.

7 Jan 2015

New intervention study examines health outcomes among private-pay home care recipients

Researchers from Harvard Medical School's Department of Health Care Policy have launched a joint partnership with ClearCare, a company that provides a software platform for home care agencies, and Right at Home, senior home care franchise.

7 Jan 2015

LSNE's Harvey Road facility receives approval to manufacture drug product for US distribution

Lyophilization Services of New England, Inc. announced today that following an FDA Pre-Approval Inspection (PAI) in November 2014, their Harvey Road manufacturing site has received approval to manufacture commercial drug product for US distribution.

7 Jan 2015

Personal traits may help protect police officers from PTSD symptoms

Personal traits such as resilience, satisfaction with life and a grateful disposition may help shield police officers from symptoms of post-traumatic stress disorder (PTSD) in the aftermath of a natural disaster.

7 Jan 2015

UCLA researchers develop method that defines unique stages of reprogramming skin cells

In a groundbreaking study that provides scientists with a critical new understanding of stem cell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first-of-its-kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embryo.

7 Jan 2015

Nearly one-quarter of parents report making change from rear-facing to forward-facing car seats

Using a rear-facing car seat until a child is age two reduces risk of serious injury, but close to one-quarter of parents report they turned the seat around before their child was even one year old, according to a new University of Michigan study.

7 Jan 2015

People working in prisons, secure hospitals are at increased risk of developing work-related stress

People working in prisons and in secure hospitals in the UK are at considerable risk of work-related stress, exhaustion and depression. This raises serious concerns for safety.

7 Jan 2015

Real-time RT-PCR TaqMan assay helps differentiate active pulmonary TB from LTBI

One of the roadblocks to the eradication of tuberculosis (TB) is the difficulty in identifying patients with latent TB infections (LTBI). Neither the tuberculin skin test (TST) nor interferon-gamma release assays (IGRAs) are capable of distinguishing active from latent infection or predicting the chance of reactivation.

7 Jan 2015

Very small changes in blood acidity level may have detrimental impact on patients with CKD

A University of Manchester scientist has discovered that very small changes in the level of acidity in blood may have a detrimental impact on the health of patients with kidney disease.

7 Jan 2015

Study highlights public health significance of depression among U.S. adolescents

A recent study published in the January 2015 issue of the Journal of the American Academy of Child and Adolescent Psychiatry underscores the important public health significance of depression among U.S. adolescents.

7 Jan 2015

Taiwan Biophotonic releases DOE reflective sensor for fingerless wrist-worn pulse oximeters

Taiwan Biophotonic Co., a leading provider of non-invasive vital signs sensing solutions, today announced the release of its DOE reflective sensor for fingerless wrist-worn pulse oximeters, which makes a quantum leap forward in the wearable healthcare and medical devices.

7 Jan 2015

Medical News

ContraVir granted Type B meeting with FDA to discuss proposal for FV-100 Phase 3 trial

Certain patients with type 2 diabetes, renal impairment discouraged from taking metformin

McGill University researchers identify network of complex neurons in the brain

Researchers detect close functional link between two brain regions for 'absolute pitch'

Study: Almost 40% of people with abnormal results ignore bowel cancer screening tests

More insight into influence of obesity on distribution, elimination of drugs needed, say experts

Arcturus to exhibit new mRNA therapeutics pipeline at two healthcare conferences

Everyday actions could help prevent spread of flu among college students

Researchers examine ischemic complications in patients who receive flow-diverting stents

Novel drug delivery technique uses graphene to deliver two anticancer drugs sequentially to cancer cells

New intervention study examines health outcomes among private-pay home care recipients

LSNE's Harvey Road facility receives approval to manufacture drug product for US distribution

Personal traits may help protect police officers from PTSD symptoms

UCLA researchers develop method that defines unique stages of reprogramming skin cells

Nearly one-quarter of parents report making change from rear-facing to forward-facing car seats

People working in prisons, secure hospitals are at increased risk of developing work-related stress

Real-time RT-PCR TaqMan assay helps differentiate active pulmonary TB from LTBI

Very small changes in blood acidity level may have detrimental impact on patients with CKD

Study highlights public health significance of depression among U.S. adolescents

Taiwan Biophotonic releases DOE reflective sensor for fingerless wrist-worn pulse oximeters

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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