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New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center, led by Chao Cheng, PhD, have identified a gene signature in E2F4 that is predictive of estrogen receptor positive (ER+) breast cancer.

8 Jan 2015

Current flu vaccine still offers protection, says Loyola infectious disease specialist

In baseball, three strikes and you're out. The most common annual vaccine targets three strains of flu virus. This year, two vaccine strains are spot on and successfully matched. One strain is partially mismatched, but still believed to offer partial coverage for that strain. The current flu vaccine is still in the game and, more importantly, keeping people well and on the playing field, says a Loyola University Medical Center infectious disease specialist.

8 Jan 2015

Better physical functioning associated with remission of general anxiety, PTSD symptoms

In a two-year longitudinal study involving 13 intensive care units in four U.S. hospitals, researchers found that better physical functioning — basic and complex activities considered essential for maintaining independence — is associated with remission of general anxiety and post-traumatic stress disorder (PTSD) symptoms. These findings may help clinicians be better prepared for caring for the growing number of survivors of critical illness, potentially leading to a better quality of recovery for patients.

8 Jan 2015

Johns Hopkins-led study offers strategy to eradicate HIV

Luring dormant HIV out of hiding and destroying its last cure-defying holdouts has become the holy grail of HIV eradication, but several recent attempts to do so have failed. Now the findings of a Johns Hopkins-led study reveal why that is and offer a strategy that could form a blueprint for a therapeutic vaccine to eradicate lingering virus from the body.

8 Jan 2015

American Migraine Foundation plans to create Migraine Patient Registry and Biorepository

Migraine affects 36 million Americans, can have a major impact on patients' quality of life, and even on their relationships. The World Health Organization estimates that migraine is the third most prevalent medical disorder in the world, the 4th most disabling among women and the 7th most disabling overall.

8 Jan 2015

ACS announces launch of new initiative to increase membership

Today the American College of Surgeons announced the launch of a new initiative aimed at stimulating more young surgeons (defined as under the age of 45) to become involved in the organization and increase membership.

8 Jan 2015

Debiopharm receives FDA Fast Track designation for anti-infectious agent Debio 1450

Debiopharm Group, a Swiss-based global biopharmaceutical company, today announced that the US Food and Drug Administration granted Fast Track designation to its anti-infectious agent Debio 1450, a highly potent antibiotic specifically active against all Staphylococcus species.

8 Jan 2015

Survey shows radiation oncologists desire for more formal guidance to improve peer review process

Peer review is a common practice in medicine to support the complementary, multidisciplinary team approach in healthcare. A 2013 survey of radiation oncologists indicates that they would like more formal recommendations and guidance in order to improve the peer review process, according to a study published in the January-February 2015 issue of Practical Radiation Oncology, the clinical practice journal of the American Society for Radiation Oncology.

8 Jan 2015

Improving headache treatment could reduce health care spending, new study suggests

Each year more than 12 million Americans visit their doctors complaining of headaches, which result in lost productivity and costs of upward of $31 billion annually. A new study by researchers from Beth Israel Deaconess Medical Center suggests some of that cost could be offset by physicians ordering fewer tests and an increased focus on counseling about lifestyle changes.

8 Jan 2015

New guidance recommends use of primary HPV test for cervical cancer screening

About 80 million U.S. women ages 25 to 65 should be screened periodically by their health care providers for cervical cancer. At present, the standard way to do that is a Pap smear alone, or co-testing using both a Pap smear and a human papillomavirus (HPV) test.

8 Jan 2015

Findings could accelerate development of prebiotic medicines for bowel problems, autoimmune diseases

Bacteria that have evolved to eat their way through yeast in the human gut could inform the development of new treatments for people suffering from bowel diseases.

8 Jan 2015

$ProNAi enrolls first patient in PNT2258 Phase II study for treatment of refractory or relapsed DLBCL$

ProNAi enrolls first patient in PNT2258 Phase II study for treatment of refractory or relapsed DLBCL

ProNAi Therapeutics Inc., a private hematology/oncology company dedicated to developing and commercializing a new class of therapeutics based on its proprietary DNAi platform, today reported that the first patient with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) has enrolled in the "Wolverine" Phase II study and been treated with PNT2258.

8 Jan 2015

Helsinn, Pharmacosmos sign license agreement for commercialization of Monofer in the US

Helsinn Group and Pharmacosmos A/S today jointly announce that they have entered into an agreement for the exclusive US commercialization rights to Monofer, an innovative intravenous iron replacement therapy under development for the treatment of Iron Deficiency Anemia.

8 Jan 2015

Canadian Blood Services, OPSEU reach tentative agreement to support employees in Ontario

Today, Canadian Blood Services announced that it has reached a tentative agreement with the Ontario Public Service Employees Union, representing its support employees in Ontario.

8 Jan 2015

Sciformix opens new European office in Manchester, UK

Sciformix Corporation, a leading Scientific Process Organization, has opened a new office in Manchester, UK expanding its global presence and footprint to include the European region.

8 Jan 2015

Fast-track diagnostics releases CE-labelled Real-time PCR kit to detect Zaire Ebolavirus

Fast-track diagnostics, a global leader in the design, development and manufacture of infectious disease detection kits, has released a CE labelled Real-time PCR kit for the detection of the Zaire Ebolavirus – the strain responsible for the current outbreak in West Africa.

8 Jan 2015

Carl Zeiss Meditec to invest in Oraya Therapy for treatment of wet AMD

Carl Zeiss Meditec AG and Oraya Therapeutics, Inc. jointly announced today that the companies have entered into a collaboration agreement under which Carl Zeiss Meditec will provide funding to Oraya over a period of up to two years for the implementation of Oraya’s growth strategy, and in turn receive rights in the company reaching up to a majority stake after two years.

8 Jan 2015

Ferrer partners with Cipher Pharmaceuticals to bring Ozenoxacin to the Canadian market

Ferrer, a privately-held Spanish pharmaceutical company, today announces that it has licensed commercialisation rights for Ozenoxacin one per cent cream in Canada to Cipher Pharmaceuticals Inc.

8 Jan 2015

Research findings could lead to new drug design for neurological diseases

A new intermediate step and unexpected enzymatic activity in a metabolic pathway in the body, which could lead to new drug design for psychiatric and neurodegenerative diseases, has been discovered by researchers at Georgia State University.

8 Jan 2015

Combination therapy can reduce recurrence of small, HER2-positive breast tumors

In a phase 2 clinical trial, women with small (stage 1), HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were highly unlikely to have the cancer recur within three years of treatment, investigators at Dana-Farber Cancer Institute and other institutions report in a paper published today by the New England Journal of Medicine.

8 Jan 2015

Medical News

New opportunity for developing simple test to measure E2F4 activity in ER+ breast cancer patients

Current flu vaccine still offers protection, says Loyola infectious disease specialist

Better physical functioning associated with remission of general anxiety, PTSD symptoms

Johns Hopkins-led study offers strategy to eradicate HIV

American Migraine Foundation plans to create Migraine Patient Registry and Biorepository

ACS announces launch of new initiative to increase membership

Debiopharm receives FDA Fast Track designation for anti-infectious agent Debio 1450

Survey shows radiation oncologists desire for more formal guidance to improve peer review process

Improving headache treatment could reduce health care spending, new study suggests

New guidance recommends use of primary HPV test for cervical cancer screening

Findings could accelerate development of prebiotic medicines for bowel problems, autoimmune diseases

ProNAi enrolls first patient in PNT2258 Phase II study for treatment of refractory or relapsed DLBCL

Helsinn, Pharmacosmos sign license agreement for commercialization of Monofer in the US

Canadian Blood Services, OPSEU reach tentative agreement to support employees in Ontario

Sciformix opens new European office in Manchester, UK

Fast-track diagnostics releases CE-labelled Real-time PCR kit to detect Zaire Ebolavirus

Carl Zeiss Meditec to invest in Oraya Therapy for treatment of wet AMD

Ferrer partners with Cipher Pharmaceuticals to bring Ozenoxacin to the Canadian market

Research findings could lead to new drug design for neurological diseases

Combination therapy can reduce recurrence of small, HER2-positive breast tumors

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

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