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Study: Fast-food outlets in inner city neighborhoods linked to risk of diabetes, obesity

How close you are to fast-food outlets may be linked to your risk of Type-2 diabetes and obesity a new study led by the University of Leicester has discovered.

12 Nov 2014

New treatment regimen for hepatitis C in transplant patients produces promising results

A new treatment regimen for hepatitis C, the most common cause of liver cancer and transplantation, has produced results that will transform treatment protocols for transplant patients, according to research published online today in the New England Journal of Medicine.

12 Nov 2014

USC researcher receives first Broad Fellowship to study kidney stem cells

What makes stem cells develop into kidneys? Lori O'Brien, a postdoctoral research associate in the laboratory of Andy McMahon, has received the first Broad Fellowship to help answer this question.

12 Nov 2014

Studies evaluate traditional management of heart attack patients after discharge from hospital

Beta-blockers have been a cornerstone in the treatment of heart attack survivors for more than a quarter of a century. However, many of the data predate contemporary medical therapy such as reperfusion, statins, and antiplatelet agents, and recent data have called the role of beta-blockers into question.

12 Nov 2014

Effecting changes to FosB gene could help control addiction, depression

Regulation of a single, specific gene in a brain region related to drug addiction and depression is sufficient to reduce drug and stress responses, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published October 27 online in the journal Nature Neuroscience.

12 Nov 2014

Pretreatment ILD is a risk factor for developing radiation pneumonitis in stage I NSCLC patients

Pretreatment interstitial lung disease (ILD) is a significant risk factor for developing symptomatic and severe radiation pneumonitis in stage I non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiation therapy (SBRT) alone.

12 Nov 2014

Antibiograms could improve antibiotic effectiveness, help address problems with antibiotic resistance

Use of "antibiograms" in skilled nursing facilities could improve antibiotic effectiveness and help address problems with antibiotic resistance that are becoming a national crisis, researchers conclude in a new study.

12 Nov 2014

Prescription opioids involved in 67.8% of nationwide ED visits in 2010, find researchers

Researchers from Rhode Island and The Miriam hospitals and the Stanford University School of Medicine have found that prescription opioids, including methadone, were involved in 67.8 percent of (or over 135,971 visits to) nationwide emergency department (ED) visits in 2010, with the highest proportion of opioid overdoses occurring in the South.

12 Nov 2014

Research opens new potential target against enterics

In research published in Nature Chemical Biology, scientists from RIKEN in Japan have discovered a surprisingly simple mechanism through which enterics can adjust to the very different oxygen environments inside the human gut and outside.

12 Nov 2014

Scientists identify new therapeutic targets, screening test to uncover compounds for memory disorders

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have identified a number of new therapeutic targets for memory disorders and have developed a new screening test to uncover compounds that may one day work against those disorders.

12 Nov 2014

RPCI researchers identify two novel candidate prognostic markers for ovarian cancer

Cancer researchers at Roswell Park Cancer Institute have identified two independent classes of novel candidate prognostic markers for ovarian cancer, advancing efforts to develop targeted therapies for the disease. The findings resulted from two separate studies published in the peer-reviewed journal PLoS ONE and based on data from The Cancer Genome Atlas (TCGA), the world's largest public database on gene expression in different tumor types.

12 Nov 2014

Enterome, AbbVie to develop novel diagnostic products, therapies for microbiome-related diseases

ENTEROME Bioscience SA, a pioneer in the development of therapeutic solutions (drugs and diagnostics) based on a thorough understanding of the gut microbiome, announces that it has entered into a collaborative development agreement with AbbVie.

12 Nov 2014

University of Melbourne researcher explores impact of living with chronic wounds

People who live with chronic wounds are often disadvantaged financially and emotionally and remain a hidden aspect of our healthcare system.

12 Nov 2014

CMS to cover low-dose CT screening for lung cancer

The Centers for Medicare and Medicaid Services today recognized the importance of lung cancer screening, announcing today that it will cover low-dose computed tomography (CT) screening, or "CAT" scans , for high-risk current and former smokers. The decision validates Mount Sinai's longstanding commitment to providing access to this essential screening tool.

12 Nov 2014

Susan Tolle to be awarded 2014 MacLean Center Prize in Clinical Ethics

The 2014 MacLean Center Prize in Clinical Ethics, an award of $50,000, will be presented to Susan Tolle, MD, a former MacLean Center fellow who has pioneered efforts to improve communication between health care providers and patients regarding end-of-life care.

12 Nov 2014

Tdap vaccination during pregnancy not associated with increased risk of preterm delivery

Among approximately 26,000 women, receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during pregnancy was not associated with increased risk of preterm delivery or small-for-gestational-age birth or with hypertensive disorders of pregnancy, although a small increased risk of being diagnosed with chorioamnionitis (an inflammation of the membranes that surround the fetus) was observed, according to a study in the November 12 issue of JAMA.

12 Nov 2014

Mayo Clinic study finds that chromosomal rearrangements can help trace lineage of lung cancer

A diagnostic test based on chromosomal rearrangements can trace the lineage of lung cancer to determine whether two separate lung cancers in the same patient are independent tumors or a tumor that has spread to another region of the lung, a Mayo Clinic study has found. For patients with multiple tumors, that distinction could mean the difference between early stage cancer that may be cured by surgery and incurable late-stage disease.

12 Nov 2014

Hospice care lowers hospitalization, ICU admissions and invasive procedures for Medicare patients

Medicare patients with poor prognosis cancers who received hospice care had significantly lower rates of hospitalization, intensive care unit (ICU) admissions and invasive procedures at the end of life, along with significantly lower health care expenditures during the last year of life, according to a study in the November 12 issue of JAMA.

12 Nov 2014

Study examines overall survival of patients with chronic HCV infection, cirrhosis

Patients with chronic hepatitis C virus infection and advanced fibrosis or cirrhosis who attained sustained virological response (SVR) had survival comparable with that of the general population, whereas patients who did not attain SVR had reduced survival, according to a study in the November 12 issue of JAMA.

12 Nov 2014

Study reports anti-cancer activity in mice treated with experimental drug TAK-733

A University of Colorado Cancer Center study published online this week in the journal Molecular Cancer Therapeutics reports anti-cancer activity in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733, a small molecule inhibitor of MEK1/2.

12 Nov 2014

Medical News

Study: Fast-food outlets in inner city neighborhoods linked to risk of diabetes, obesity

New treatment regimen for hepatitis C in transplant patients produces promising results

USC researcher receives first Broad Fellowship to study kidney stem cells

Studies evaluate traditional management of heart attack patients after discharge from hospital

Effecting changes to FosB gene could help control addiction, depression

Pretreatment ILD is a risk factor for developing radiation pneumonitis in stage I NSCLC patients

Antibiograms could improve antibiotic effectiveness, help address problems with antibiotic resistance

Prescription opioids involved in 67.8% of nationwide ED visits in 2010, find researchers

Research opens new potential target against enterics

Scientists identify new therapeutic targets, screening test to uncover compounds for memory disorders

RPCI researchers identify two novel candidate prognostic markers for ovarian cancer

Enterome, AbbVie to develop novel diagnostic products, therapies for microbiome-related diseases

University of Melbourne researcher explores impact of living with chronic wounds

CMS to cover low-dose CT screening for lung cancer

Susan Tolle to be awarded 2014 MacLean Center Prize in Clinical Ethics

Tdap vaccination during pregnancy not associated with increased risk of preterm delivery

Mayo Clinic study finds that chromosomal rearrangements can help trace lineage of lung cancer

Hospice care lowers hospitalization, ICU admissions and invasive procedures for Medicare patients

Study examines overall survival of patients with chronic HCV infection, cirrhosis

Study reports anti-cancer activity in mice treated with experimental drug TAK-733

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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