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Regeneron, Sanofi report positive results from dupilumab Phase 2b study in patients with asthma

Regeneron Pharmaceuticals, Inc. and Sanofi today announced positive results from the interim analysis of a dose-ranging Phase 2b study of dupilumab in adult patients with uncontrolled moderate-to-severe asthma. Dupilumab is an investigational therapy blocking IL-4 and IL-13, two cytokines required for the Th2 immune response.

11 Nov 2014

Sulindac drug can protect against oxidative damage due to AMD

While oxygen is essential to our planet's life force and the way we function and stay healthy, high concentrations referred to as oxidative stress may very well be the cause of more than 70 widely-spread diseases such as cancer, heart disease, neurodegenerative diseases, and eye diseases including macular degeneration.

11 Nov 2014

Lung cancer screening in NLST meets standard for cost effectiveness

Dartmouth researchers say lung cancer screening in the National Lung Screening Trial (NLST) meets a commonly accepted standard for cost effectiveness as reported in the Nov. 6 issue of the New England Journal of Medicine. This relatively new screening test uses annual low-dose CT scans to spot lung tumors early in individuals facing the highest risks of lung cancer due to age and smoking history.

11 Nov 2014

UC San Diego Health System receives Leapfrog's highest grade for patient safety

Updating its unique Hospital Safety Score, which assigns A, B, C, D and F grades to hospitals nationwide based on their ability to prevent errors, injuries and infections, UC San Diego Health System has again been awarded separate A ratings for its hospitals in Hillcrest and La Jolla by The Leapfrog Group, an independent industry watchdog.

11 Nov 2014

First steps in the origin of pancreatic cancer identified by Mayo Clinic researchers

Researchers at Mayo Clinic's campus in Jacksonville say they have identified first steps in the origin of pancreatic cancer and that their findings suggest preventive strategies to explore.

11 Nov 2014

Two new oral medications post-transplant is safe, beneficial for patients with hepatitis C

All patients with hepatitis C who receive a liver transplant will eventually infect their new livers. These transplanted organs then require anti-viral treatment before they become severely damaged. But traditional post-transplant hepatitis C therapy can take up to a year, is potentially toxic and can lead to organ rejection.

11 Nov 2014

Anxiety can accelerate conversion to Alzheimer's disease for people with mild cognitive impairment

People with mild cognitive impairment (MCI) are at increased risk of converting to Alzheimer's disease within a few years, but a new study warns the risk increases significantly if they suffer from anxiety.

11 Nov 2014

Peter Munk Cardiac Centre surgeons successfully implant novel heart device

A surgical team at the Peter Munk Cardiac Centre led by internationally-acclaimed cardiovascular surgeon, Dr. Vivek Rao, has successfully implanted a novel mechanical device, the HeartMate IIITM, into a patient with advanced heart failure.

11 Nov 2014

Innovative program benefits incapacitated patients with no family or friends

A Regenstrief Institute and Eskenazi Health study reports on an innovative program that trains and supervises volunteers who act as advocates for adults and seniors who are unable to make their own decisions due to conditions like Alzheimer's disease or coma, but have no family or friends to help them.

11 Nov 2014

UW SMPH awarded $70 million grant to continue work on Inner-City Asthma Consortium

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded the University of Wisconsin School of Medicine and Public Health a seven-year, $70 million grant for its continuing work on the Inner-City Asthma Consortium (ICAC) -- a nationwide clinical research network to evaluate and develop promising new immune-based treatments.

11 Nov 2014

New study finds that it is possible to distinguish between different hemorrhagic fevers

A new study has found it is possible to distinguish between different hemorrhagic fevers, including Marburg (Ebola cousin) and Lassa before the person becomes symptomatic.

11 Nov 2014

Study points to major role of obesity in triggering, prolonging autoimmune diseases

Autoimmune diseases like Crohn's Disease and multiple sclerosis, in which the immune system attacks its own body rather than predatory invaders, affect 5-20% of the global community. A study published recently in Autoimmunity Reviews by Prof. Yehuda Shoenfeld, the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases at Tel Aviv University's Sackler Faculty of Medicine and Head of Zabludowicz Center for Autoimmune Diseases at Chaim Sheba Medical Center, Tel Hashomer, points to the major role obesity plays in triggering and prolonging these autoimmune diseases.

11 Nov 2014

Endothelin gene expression linked to vision loss in premature babies

A gene known to play a major role in constricting blood vessels also appears to be a major player in the aberrant blood vessel growth that can destroy the vision of premature babies.

11 Nov 2014

U-M student researchers complete Detroit's first comprehensive inventory of greenhouse gas emissions

Energy use in buildings accounts for nearly two-thirds of the greenhouse gas emissions generated in Detroit, while exhaust from cars, trucks and buses is responsible for about 30 percent of the total, according to a new citywide inventory compiled by University of Michigan student researchers.

11 Nov 2014

Mice may hold clues in development of ADHD, autism and bipolar disorder

A darting mouse may hold an important clue in the development of Attention Deficit Hyperactivity Disorder (ADHD), autism and bipolar disorder, according to a study by a Vanderbilt University-led research team recently published in the Proceedings of the National Academy of Sciences.

11 Nov 2014

New treatment could halt growth of tumours in prostate cancer patients

Scientists believe a new treatment, shown to be effective in mice, could halt the growth of tumours in patients with prostate cancer.

11 Nov 2014

U-M study reveals that mothers' education can predict children's academic success

A mother knows best--and the amount of education she attains can predict her children's success in reading and math. In fact, that success is greater if she had her child later in life, according to a new University of Michigan study.

11 Nov 2014

Survey: Majority of U.S. adult women do not believe that they are up to date on vaccinations

A national survey from Rite Aid and National Foundation for Infectious Diseases reveals that the majority of adult women living in the United States do not believe they are up to date on vaccinations to protect against many preventable diseases.

11 Nov 2014

MicroMatrices, Advanced Cell Diagnostics sign preferred partnership agreement

MicroMatrices, a service provider specialised in high resolution cell type-specific analysis to characterise toxicological responses in different cell types in tissue, today announced a preferred partnership agreement with Advanced Cell Diagnostics, Inc., a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools.

From Advanced Cell Diagnostics 11 Nov 2014

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

A new drug combination for rheumatoid arthritis treats the disease just as well as other intensive treatment strategies but with less medication and fewer side effects at a significantly lower cost. Doctoral researcher Diederik De Cock (KU Leuven) describes the strategy in a new study published in Annals of Rheumatic Diseases.

11 Nov 2014

Medical News

Regeneron, Sanofi report positive results from dupilumab Phase 2b study in patients with asthma

Sulindac drug can protect against oxidative damage due to AMD

Lung cancer screening in NLST meets standard for cost effectiveness

UC San Diego Health System receives Leapfrog's highest grade for patient safety

First steps in the origin of pancreatic cancer identified by Mayo Clinic researchers

Two new oral medications post-transplant is safe, beneficial for patients with hepatitis C

Anxiety can accelerate conversion to Alzheimer's disease for people with mild cognitive impairment

Peter Munk Cardiac Centre surgeons successfully implant novel heart device

Innovative program benefits incapacitated patients with no family or friends

UW SMPH awarded $70 million grant to continue work on Inner-City Asthma Consortium

New study finds that it is possible to distinguish between different hemorrhagic fevers

Study points to major role of obesity in triggering, prolonging autoimmune diseases

Endothelin gene expression linked to vision loss in premature babies

U-M student researchers complete Detroit's first comprehensive inventory of greenhouse gas emissions

Mice may hold clues in development of ADHD, autism and bipolar disorder

New treatment could halt growth of tumours in prostate cancer patients

U-M study reveals that mothers' education can predict children's academic success

Survey: Majority of U.S. adult women do not believe that they are up to date on vaccinations

MicroMatrices, Advanced Cell Diagnostics sign preferred partnership agreement

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

AI-powered analytics and experimental validation

Membrane proteins in focus: Turning high-risk targets into routine workflows

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