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Findings support development of cysteine protease inhibitors as new drug target for AD

A team of scientists from the University of California, San Diego School of Medicine, the Medical University of South Carolina and San Diego-based American Life Science Pharmaceuticals, Inc., report that cathepsin B gene knockout or its reduction by an enzyme inhibitor blocks creation of key neurotoxic pGlu-Aβ peptides linked to Alzheimer's disease (AD). Moreover, the candidate inhibitor drug has been shown to be safe in humans.

18 Mar 2014

Viewpoints: The lesson from Florida's special election; hospital deaths; costs of treating hep C

But in recent months, the political landscape has grown bleaker [for Democrats] .... The question, of course, is why so many Republicans turned out [in the Florida special election last week] and why so few Democrats did. The answer among strategists on both sides was: Obamacare. But not in the sense that the healthcare law is so unpopular that Democrats are doomed; in fact, as more people sign up for health coverage, polls suggest that Obamacare is a little less toxic now than it was last fall. Instead, the problem is that a high-decibel debate over Obamacare has the effect of prompting conservatives to come out and vote, but not liberals (Doyle McManus, 3/16).

18 Mar 2014

More compassion, resources required to help guide treatment choices for congenital heart disease

Based on a survey of parents of children with congenital heart disease, physicians delivering the diagnosis need to do a better job of showing compassion, ensuring parents understand all their options and providing easily understandable information, according to a new study published in the February edition of the journal, Pediatric Cardiology.

18 Mar 2014

New case study reveals how to safely switch between anticoagulants for stroke prevention

With the availability of newer oral anticoagulants, the latest online case study from NPS MedicineWise helps health professionals navigate this changing area and understand the range of treatment options for managing stroke prevention in people with non-valvular atrial fibrillation.

18 Mar 2014

Researchers create new line of human embryonic stem cells

Researchers at the University of Washington have successfully created a line of human embryonic stem cells that have the ability to develop into a far broader range of tissues than most existing cell lines.

18 Mar 2014

Researcher to test brain stimulation, gait training to improve patients' ability to walk after stroke

A University of Illinois at Chicago researcher will test whether brain stimulation combined with gait training can improve patients' ability to walk after a stroke, under a $1.5 million grant from the National Institute of Child Health and Human Development.

18 Mar 2014

ChromaTrap™ Chromatin Immunoprecipitation technology receives positive commentary in published paper

Porvair Sciences reports on positive commentary by researchers in published papers citing how using the fast, sensitive ChromaTrap™ Chromatin Immunoprecipitation (ChIP) technology has benefited their research.

From Chromatrap® - Porvair Sciences Ltd 18 Mar 2014

White House to expand federal marketplace insurance plan standards in 2015, broaden choices

The Obama administration will rely less on state insurance regulators and private groups in determining which plans will meet standards to sell insurance on the federal marketplace.

18 Mar 2014

First Edition: March 18, 2014

Today's headlines include reports about the Obama administration announcement that more than 5 million people have enrolled in coverage under the health law -- an increase of about 800,000 in the last two weeks.

18 Mar 2014

Researchers examine how diabetes drug can benefit cancer patients

For several years, a class of anti-diabetic drugs known as biguanides, has been associated with anti-cancer properties. A number of retrospective studies have shown that the widely used diabetes drug metformin can benefit some cancer patients.

18 Mar 2014

Virginia business, hospital groups launch ads promoting Medicaid compromise

The radio promotion is trying to drum up support for a private option plan that would help insure thousands of low-income residents. Gov. Terry McAuliffe also is barnstorming around the state seeking to put pressure on Republican lawmakers who are opposed to the expansion of Medicaid.

18 Mar 2014

CorTechs secures new Series B financing

Medical software developer CorTechs Labs, Inc. is pleased to announce it has secured new Series B financing to support the company's rapid growth. The round was led by Genting Berhad via its indirect wholly-owned subsidiary, Dragasac Limited, a company incorporated in the Isle of Man.

18 Mar 2014

Compound from "third-hand smoke" damages DNA and potentially cause cancer

Leftover cigarette smoke that clings to walls and furniture is a smelly nuisance, but now research suggests that it could pose a far more serious threat, especially to young children who put toys and other smoke-affected items into their mouths.

18 Mar 2014

Sequencing reveals genetic diversity in hospital-acquired bacterium

Using genome sequencing, National Institutes of Health scientists and their colleagues have tracked the evolution of the antibiotic-resistant bacterium Klebsiella pneumoniae sequence type 258 (ST258), an important agent of hospital-acquired infections.

18 Mar 2014

Adolescents who have ACL reconstruction are more likely to demonstrate osteoarthritic changes later in life

Researchers presented results today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Specialty Day in New Orleans that adolescents who have an Anterior Cruciate Ligament (ACL) reconstruction are more likely to demonstrate osteoarthritic changes later in life.

18 Mar 2014

House ties 'doc fix' to a delay in the individual mandate

The Senate is expected to refuse to accept the Republican plan to fix the way Medicare pays doctors and that could fray a bipartisan effort to find a long-term solution to the problem.

18 Mar 2014

Study estimates a third of uninsured won't enroll in health plans

The Fiscal Times reports that the study by Bankrate.com shows government outreach efforts are falling short. Meanwhile, news outlets look at enrollment efforts in New Jersey, Montana, Maine, Washington, Pennsylvania, Ohio and California.

18 Mar 2014

Over 40% of pregnant low-income women after diagnosis of false labor do not want to be sent home

More than 40 percent of pregnant low-income women discharged from the hospital after a diagnosis of false or early labor did not want to be sent home, with the most common reasons being that they were in too much pain or lived too far away, according to a study by Baylor University's Louise Herrington School of Nursing (LHSON) and Parkland Health & Hospital System.

18 Mar 2014

Uptake for HPV jab below 80% required to make significant impact on cervical cancer

Young women who are most at risk of developing cervical cancer are the least likely to be offered the protective HPV jab and to complete the full course when they are, reveals research published online in the journal Sexually Transmitted Infections.

18 Mar 2014

Merck Millipore announces joint development agreement with Sysmex Corporation

Merck Millipore, the Life Science division of Merck, today announced a clinical research, licensing and joint development agreement with Sysmex Corporation of Japan.

From Sysmex America, Inc. 18 Mar 2014

Medical News

Findings support development of cysteine protease inhibitors as new drug target for AD

Viewpoints: The lesson from Florida's special election; hospital deaths; costs of treating hep C

More compassion, resources required to help guide treatment choices for congenital heart disease

New case study reveals how to safely switch between anticoagulants for stroke prevention

Researchers create new line of human embryonic stem cells

Researcher to test brain stimulation, gait training to improve patients' ability to walk after stroke

ChromaTrap™ Chromatin Immunoprecipitation technology receives positive commentary in published paper

White House to expand federal marketplace insurance plan standards in 2015, broaden choices

First Edition: March 18, 2014

Researchers examine how diabetes drug can benefit cancer patients

Virginia business, hospital groups launch ads promoting Medicaid compromise

CorTechs secures new Series B financing

Compound from "third-hand smoke" damages DNA and potentially cause cancer

Sequencing reveals genetic diversity in hospital-acquired bacterium

Adolescents who have ACL reconstruction are more likely to demonstrate osteoarthritic changes later in life

House ties 'doc fix' to a delay in the individual mandate

Study estimates a third of uninsured won't enroll in health plans

Over 40% of pregnant low-income women after diagnosis of false labor do not want to be sent home

Uptake for HPV jab below 80% required to make significant impact on cervical cancer

Merck Millipore announces joint development agreement with Sysmex Corporation

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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