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Chemo and radiation can kill more cancer cells and spare healthy ones, suggests Rutgers research

What if there were a way to make chemotherapy and radiation more effective as cancer treatments than they are today, while also getting rid of debilitating side effects that patients dread? A new study led by Alexey Ryazanov, a professor of pharmacology at Rutgers Robert Wood Johnson Medical School and member of the Rutgers Cancer Institute of New Jersey, suggests the day that happens could be getting closer.

27 Feb 2014

Penn researchers identify possible new way to fight rare blood disorder

A University of Pennsylvania research team has defined a possible new way to fight a disease that is currently treatable only with the most expensive drug available for sale in the United States. In a study published this month in Blood, the Penn team describes the strategy, based on the oldest part of the human immune system - called "complement" -- that could turn out to be less costly and more effective for the majority of patients with a rare blood disorder.

27 Feb 2014

Medicare Part D cost-saving plan draws opposition on several fronts

Among other things, the proposal would limit the types of antidepressants -- and other kinds of drugs -- that are available to Medicare beneficiaries. Drug industry and insurer groups are lining up against the change.

27 Feb 2014

Study identifies promising target for new drugs to treat lethal form of brain cancer

A molecule in cells that shuts down the expression of genes might be a promising target for new drugs designed to treat the most frequent and lethal form of brain cancer, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

27 Feb 2014

Study provides novel insight into the impact of genes on Huntington's disease

A study led by researchers at Boston University School of Medicine provides novel insight into the impact that genes may have on Huntington's disease (HD). The study, published online in PLOS Genetics, identified specific small segments of RNA (called micro RNA or miRNA) encoded in DNA in the human genome that are highly expressed in HD.

27 Feb 2014

UH scientists working to develop next generation of prostate cancer therapies

A University of Houston scientist and his team are working to develop the next generation of prostate cancer therapies, which are targeted at metabolism.

27 Feb 2014

Further support for hippocampal volume as psychosis biomarker

Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes provide further evidence that reduced hippocampal volume is a consistent feature of schizophrenia.

27 Feb 2014

Advanced paternal age effects extend to several psychiatric disorders

The effect of advanced paternal age at childbearing on the psychiatric morbidity risk of their children extends to several psychiatric disorders and particularly bipolar disorder, findings from a sibling-comparison study show.

27 Feb 2014

New corneal layer important for intraocular pressure maintenance

UK researchers have found that a newly discovered layer of the human eye is an important part of the structural tissue that helps to maintain intraocular pressure and thus may play a role in the development of glaucoma.

27 Feb 2014

H4 receptor activation plays part in NSCLC progression

Histamine H4 receptor activation decreases epithelial-to-mesenchymal transmission in non-small-cell lung cancer, Chinese research shows.

27 Feb 2014

Motesanib boosts carboplatin/paclitaxel efficacy in NSCLC

Adding motesanib to carboplatin/paclitaxel significantly improves overall survival in Asian patients with nonsquamous non-small-cell lung cancer compared with carboplatin/paclitaxel alone, researchers report.

27 Feb 2014

University of Sheffield showcases its world-class scientists and facilities to businesses

National and international businesses will find out how the University of Sheffield’s world-class scientists and state-of-the-art facilities can take their research and development to the next level during a free networking event on Thursday.

27 Feb 2014

Babies delivered by C-section may be more likely to become obese

Babies that are delivered by caeserean section are more likely to become overweight or obese as adults, according to researchers from Imperial College, London.

27 Feb 2014

NxStage Medical revenue increases 7% to $69.4 million in fourth quarter 2013

NxStage Medical, Inc., a leading manufacturer of innovative dialysis products, today reported record financial results for the three and twelve months ended December 31, 2013, that include revenue slightly above its recent guidance.

27 Feb 2014

Astellas' isavuconazole receives QIDP designation from FDA for zygomycosis treatment

Astellas Pharma Global Development, Inc., a subsidiary of Tokyo-based Astellas Pharma Inc., announced today that the U.S. Food and Drug Administration designated isavuconazole as a Qualified Infectious Disease Product (QIDP) for the treatment of invasive mucormycosis (also known as zygomycosis), a life-threatening invasive fungal infection caused by certain emerging molds.

27 Feb 2014

Ophthotech reports net loss of $20.4 million for fourth quarter 2013

Ophthotech Corporation today announced financial results for the fourth quarter and full year ended December 31, 2013 and provided an update on the Company's business and product development programs.

27 Feb 2014

Covidien closes acquisition of Given Imaging

Covidien plc today announced that it has closed its acquisition of Given Imaging Ltd., providing the company additional scale and scope to serve a significant medical specialty, the multibillion dollar global gastrointestinal (GI) market.

27 Feb 2014

Sarepta Therapeutics reports non-GAAP net loss of $29.1 million for Q4 2013

Sarepta Therapeutics, Inc., a developer of innovative RNA-based therapeutics, today reported financial results for the three months and year ended December 31, 2013, and provided an update of recent corporate developments.

27 Feb 2014

First Edition: February 27, 2014

Today's headlines include a number of stories about Obama past and present administration officials -- notably, former Secretary of State Hillary Clinton and Vice President Joe Biden -- who are stepping up to "sell" people on enrolling in new health law insurance coverage.

27 Feb 2014

Poll: Just 12% of parents without coverage take breastfeeding support classes

Just 12 percent of parents without insurance coverage take breastfeeding support classes that can offer crucial support and encourage new moms to breastfeed, according to a new University of Michigan C.S. Mott Children's Hospital National Poll on Children's Health.

27 Feb 2014