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Study reveals pathogenic factor that triggers prion and neurodegenerative diseases

Transmissible spongiform encephalopathy or prion disease is triggered by the conversion from cellular prion protein to pathogenic prion protein.

12 Dec 2013

Early docetaxel drug with ADT increases survival of men with metastatic prostate cancer

Men with hormone-sensitive metastatic prostate cancer who received the chemotherapy drug docetaxel given at the start of standard hormone therapy lived longer than patients who received hormone therapy alone, according to early results from a National Institutes of Health-supported randomized controlled clinical trial.

12 Dec 2013

Infants likely becoming exposed to potentially harmful substances via PCPs

Through lotions, shampoos and other personal care products (PCPs), infants and toddlers are likely becoming exposed to potentially harmful substances, called parabens, at an even higher level than adult women in the U.S., researchers have reported.

12 Dec 2013

Study: Younger women more likely to be hospitalized and die from acute myocardial infarction

Young women, ages 55 years or below, are more likely to be hospitalized for an acute myocardial infarction (AMI) and to die within the first 30 days than men in the same age group, according to a new study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

12 Dec 2013

Medivir initiates phase IIa trial to evaluate efficacy of simeprevir combination therapy in HCV-infected patients

Medivir AB (STO:MVIR-B) (OMX: MVIR), announces the initiation of a phase IIa trial in chronic genotype 1 hepatitis C infected patients to evaluate the efficacy, safety and tolerability of a 12-week combination therapy of simeprevir, TMC647055 and JNJ56914845, a NS5A replication complex inhibitor.

12 Dec 2013

Viewpoints: 'Small-bore' budget deal better than shutdown; Calif. battle on medical malpractice; Obama should turn to health quality

The bipartisan spending deal announced Tuesday night by Senate Budget Chairman Patty Murray, D-Wash., and House Budget Chairman Paul Ryan, R-Wis., barely qualifies as a tweak. It would not make meaningful progress on reducing projected deficits, ... BY any measure it is a small-bore deal, but it as at least something - a toehold that prevents a serious fall and might, optimistically, enable a climb to safety. ... It would also partially undo the inflexible across-the-board spending cuts known as sequestration. Longer term, the accord could signal the beginning of a more constructive relationship in Congress (12/10).

12 Dec 2013

Blows to head may affect the brain's white matter and cognition even without concussion

New research suggests that even in the absence of a concussion, blows to the head during a single season of football or ice hockey may affect the brain's white matter and cognition, or memory and thinking abilities. The study is published in the December 11, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology. White matter is brain tissue that plays an important role in the speed of nerve signals.

12 Dec 2013

Researchers discover new mechanism in brain which controls tics in children with TS

A mechanism in the brain which controls tics in children with Tourette Syndrome (TS) has been discovered by scientists at The University of Nottingham.

12 Dec 2013

New Journal presents techniques for finding new uses for approved drugs

Mary Ann Liebert, Inc., publishers is pleased to announce Drug Repurposing, Rescue, and Repositioning, a dynamic new peer-reviewed journal that will present techniques and tools for finding new uses for approved drugs—particularly for disorders where no animal model, physiologic abnormality, biochemical pathway, or molecular target has been identified.

12 Dec 2013

Researchers refute avalanche theory on cancer

First, the number of chromosomes in a cell changes, then an avalanche of further mutations occur that transform the cell into a cancer cell, according to a well-known - but untested - theory.

12 Dec 2013

New guidelines to manage heart failure in children

Heart failure in children is an important cause of childhood health problems and death. The Children's Heart Failure Study Group of the Canadian Cardiovascular Society, in collaboration with the Canadian Pediatric Cardiology Association, has developed new guidelines to assist practitioners in primary care and emergency departments to recognize and successfully manage heart failure in children with undiagnosed heart disease and symptoms of possible heart failure.

12 Dec 2013

New drug-resistant strain of bird flu appears to retain ability to cause serious disease in humans

Researchers at the Icahn School of Medicine at Mount Sinai reported that a virulent new strain of influenza - the virus that causes the flu - appears to retain its ability to cause serious disease in humans even after it develops resistance to antiviral medications. The finding was included in a study that was published today in the journal Nature Communications.

12 Dec 2013

Heartland Food Products Group makes key breakthrough in sucralose manufacturing technology

Heartland Food Products Group, one of world's leading producers and marketers of zero calorie sweeteners and liquid water enhancers for consumer markets and its sister corporation Lexington Pharmaceuticals announce a breakthrough in sucralose manufacturing technology.

12 Dec 2013

Dementia much higher among Native Americans and African-Americans

In the first study to look at racial and ethnic differences in dementia risk among older adults with type 2 diabetes, researchers found that dementia was much higher among Native Americans and African-Americans and lowest among Asian-Americans.

12 Dec 2013

Special treatment? Examining who on Capitol Hill has to get coverage on the health law's exchanges

News outlets take a closer look at the circumstances around how members of Congress and their staffs are navigating getting health coverage on the DC insurance exchange -- and just who is required to do so and by when.

12 Dec 2013

GSK's FluLaval Quadrivalent vaccine effective in reducing flu cases in children

GlaxoSmithKline plc announced today that a peer-reviewed study issued online by the New England Journal of Medicine has reported that GSK's FluLaval® Quadrivalent reduced flu cases among children ages 3-8 by 55.4% overall and lowered the risk of developing moderate-to-serious flu illness by 73.1%.

12 Dec 2013

Synthetic Biologics prices underwritten public offering of common stock at $1.00 per share

Synthetic Biologics, Inc., a developer of product candidates focused on the prevention and treatment of serious infectious and other diseases, announced today the pricing of an underwritten public offering of 11,500,000 shares of common stock at a public offering price of $1.00 per share.

12 Dec 2013

ScinoPharm constructs Changshu plant in China

ScinoPharm today announced that the company has completed construction of its Changshu plant on a 16-acre (6.5-hectare) site.

12 Dec 2013

New study evaluates disparity between planned versus actual patient enrollment in oncology trials

Expected and actual patient enrollment differs by an average 7.1% among the Phase 3 oncology trials examined in a recent Cutting Edge Information study.

12 Dec 2013

Immunocellular Therapeutics reports positive results from ICT-107 Phase II study in glioblastoma patients

ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") announced that ICT-107, its dendritic cell-based vaccine, demonstrated a statistically significant increase in progression-free survival (PFS) in patients with newly diagnosed glioblastoma multiforme (GBM) in its randomized, placebo-controlled phase II trial.

12 Dec 2013

Medical News

Study reveals pathogenic factor that triggers prion and neurodegenerative diseases

Early docetaxel drug with ADT increases survival of men with metastatic prostate cancer

Infants likely becoming exposed to potentially harmful substances via PCPs

Study: Younger women more likely to be hospitalized and die from acute myocardial infarction

Medivir initiates phase IIa trial to evaluate efficacy of simeprevir combination therapy in HCV-infected patients

Viewpoints: 'Small-bore' budget deal better than shutdown; Calif. battle on medical malpractice; Obama should turn to health quality

Blows to head may affect the brain's white matter and cognition even without concussion

Researchers discover new mechanism in brain which controls tics in children with TS

New Journal presents techniques for finding new uses for approved drugs

Researchers refute avalanche theory on cancer

New guidelines to manage heart failure in children

New drug-resistant strain of bird flu appears to retain ability to cause serious disease in humans

Heartland Food Products Group makes key breakthrough in sucralose manufacturing technology

Dementia much higher among Native Americans and African-Americans

Special treatment? Examining who on Capitol Hill has to get coverage on the health law's exchanges

GSK's FluLaval Quadrivalent vaccine effective in reducing flu cases in children

Synthetic Biologics prices underwritten public offering of common stock at $1.00 per share

ScinoPharm constructs Changshu plant in China

New study evaluates disparity between planned versus actual patient enrollment in oncology trials

Immunocellular Therapeutics reports positive results from ICT-107 Phase II study in glioblastoma patients

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

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