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A boy’s bicycling death haunts a Black neighborhood. 35 years later, There’s still no sidewalk.

It's been 35 years since John Parker died after a pickup collided with the bike he was riding on Cheek Road in east Durham before school. He was 6.

8 Oct 2024

CrestOptics and Leica Microsystems announce strategic collaboration to expand capabilities of spinning disk microscopy

The collaboration between CrestOptics and Leica Microsystems combines CICERO spinning disk technology with THUNDER platform for superior microscopy solutions.

From CrestOptics 8 Oct 2024

Mosaic Therapeutics appoints Dr Barry Davies as CSO

Dr. Barry Davies joins Mosaic Therapeutics as CSO, bringing 25 years of drug discovery expertise to advance targeted oncology therapies and precision medicine.

8 Oct 2024

Study reveals osteochondritis risk in children undergoing knee surgery

Growing pains are common in maturing children, but sometimes this growth can be irregular and cause injury. Discoid lateral meniscus (DLM), a misshapen knee cartilage, is one such occurrence that can degenerate into osteochondritis dissecans, a joint disorder where the bone and joint begin to separate from the rest of the bones.

8 Oct 2024

Brainstem inflammation may explain long Covid symptoms

Damage to the brainstem – the brain's 'control center' – is behind long-lasting physical and psychiatric effects of severe Covid-19 infection, a study suggests.

8 Oct 2024

Common breast cancer therapies may speed up aging, study shows

A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center has revealed that common breast cancer treatments, including chemotherapy, radiation, and surgery, may accelerate the biological aging process in breast cancer survivors.

8 Oct 2024

FAU researchers highlight new vaccination barriers

Vaccines to prevent common and serious infectious diseases have had a greater impact on improving human health than any other medical advance of the 20th century, surpassing even sanitation and potable water. From the global eradication of smallpox in 1980 to the unprecedented development of effective and safe mRNA vaccines for COVID-19, vaccinations have played crucial roles in preventing millions of premature deaths and hospitalizations in adults and children.

8 Oct 2024

AI and imaging tools to drive personalized cancer treatments in Europe

Developing new cancer treatment tools, using imaging techniques such as PET-CT and MRI, and new radiopharmaceuticals for next-generation personalized therapies ("Theranostics") to target cancer first at the "diagnosis" phase and then at the "therapy" phase, using the same biological targets ("see to treat").

8 Oct 2024

New UCL hub to advance cancer detection with imaging tech

UCL will lead a £17 million surgical imaging hub to improve cancer detection and take part in a £12 million collaboration to help solve age and disability-related mobility issues, in a major funding award from the UKRI Engineering and Physical Sciences Research Council (EPSRC).

8 Oct 2024

Study reviews BNMs' role in understanding brain disorders

A research team from the International Research Institute for Artificial Intelligence at Harbin Institute of Technology, Shenzhen, has recently published a comprehensive review in the journal Health Data Science on the application of Brain Network Models (BNMs) in the medical field.

8 Oct 2024

SCD health disparities tied to community factors

A new study finds that preschool-aged children with sickle cell disease (SCD) who live in food deserts and have limited access to transportation are at greater risk for acute complications and hospitalizations, despite receiving free evidence-based therapy and social support, according to results published today in Blood Advances.

8 Oct 2024

Environmental factors significantly impact gene expression through epigenetic modifications

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment. The review article "Epigenetics and Environmental Health" provides an in-depth analysis of how epigenetic modifications can influence the onset and progression of various diseases, particularly cancer and cardiovascular diseases.

8 Oct 2024

Study suggests humans are approaching a biological limit to life

We've seen dramatic increases in life expectancy over the 19th and 20th centuries, thanks to healthier diets, medical advances and many other quality-of-life improvements.

8 Oct 2024

Early bedtime boosts children's gut health by increasing beneficial bacteria

Study reveals that children who go to bed early have a more diverse and healthier gut microbiome compared to late sleepers, suggesting a link between sleep habits and gut health. It also highlights key metabolic pathways that differ between early and late sleepers.

8 Oct 2024

Unexpected benzene levels in popular acne and rosacea products

Investigators have determined that a substantial portion of topical benzoyl peroxide (BPO) acne and rosacea treatments currently on the market are unstable and contain unacceptably high levels of benzene, a known human carcinogen.

7 Oct 2024

Overcoming CRISPR's side effects for therapeutic applications

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism. It's a reagent - a substance that facilitates a reaction - that combines an enzyme with a programmable RNA capable of locating specific genetic sequences. Once guided to the correct spot, the enzyme acts like a pair of scissors, cutting, replacing, or deleting sequences of DNA.

7 Oct 2024

Doxycycline increases antimicrobial resistance in the gut without disrupting microbiome diversity

Doxycycline post-exposure prophylaxis increases tetracycline resistance genes in the gut, without significantly affecting microbiome diversity in men who have sex with men and transgender women.

7 Oct 2024

GLP-1 drugs protect brain health by improving neurovascular function and reducing inflammation

Research highlights how GLP-1 receptor agonists may improve brain health by targeting the neurovascular unit, linking metabolic health to cognitive function. It suggests potential therapies for neurodegenerative diseases like Alzheimer's.

7 Oct 2024

Researchers uncover how senescent cells can both harm and heal in liver disease

Researchers developed novel genetic tools to trace, ablate, and manipulate p16^Ink4a+^ senescent cells, revealing their distinct roles in liver fibrosis and repair. Senescent macrophages promote fibrosis, while endothelial cells aid in tissue recovery.

7 Oct 2024

Low-income Medicare Advantage beneficiaries face barriers to dental, vision and hearing care

Lower-income adults with Medicare Advantage plans are more likely to have difficulty paying for dental, vision, and hearing services than higher-income beneficiaries - despite enrolling in plans that cover these benefits, according to a new study published in Health Affairs.

7 Oct 2024