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First Edition: March 25, 2013

Today's headlines include reports about the continuing outlook for progress on the federal budget as well as a variety of stories related to the health law's implementation.

25 Mar 2013

Newly discovered molecule could form the basis of anti-malaria drugs

An international study, involving researchers from Griffith University's Eskitis Institute, has discovered a molecule which could form the basis of powerful new anti-malaria drugs.

25 Mar 2013

Actavis settles patent litigation with AstraZeneca over generic version of Crestor

Actavis, Inc., a leading specialty pharmaceutical company, today announced that is has reached a settlement agreement with AstraZeneca resolving outstanding patent litigation related to Actavis' generic version of rosuvastatin calcium 5, 10, 20 and 40 mg tablets, the generic version of Crestor tablets, as well as Actavis' rosuvastatin zinc alternate salt product.

25 Mar 2013

Study shows why certain drugs that interact with serotonin receptors have harmful effects

A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution atomic structures of two kinds of human serotonin receptor.

25 Mar 2013

Konzo's harm goes beyond devastating physical effects

The harm done by konzo - a disease overshadowed by the war and drought it tends to accompany - goes beyond its devastating physical effects to impair children's memory, problem solving and other cognitive functions.

25 Mar 2013

MIT biology professor named Pew's Biomedical Researcher of the Month

Biologist Mary Gehring, Ph.D. is The Pew Charitable Trusts' featured biomedical researcher of the month for her creative research on epigenetics in plants.

25 Mar 2013

Scientists identify potential treatment for idiopathic pulmonary fibrosis

Investigators at the University of Alabama at Birmingham (UAB) have unlocked another piece of the puzzle surrounding idiopathic pulmonary fibrosis, an often fatal lung disease with no cure and no effective treatments.

25 Mar 2013

Researchers study gene variants that bear signature for inflammatory disease susceptibility

In new research published in the April 4, 2013 issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history.

25 Mar 2013

Researchers expand hematopoietic stem cells for bone marrow transplantation

More than 50,000 stem cell transplants are performed each year worldwide. A research team led by Weill Cornell Medical College investigators may have solved a major issue of expanding adult hematopoietic stem cells (HSCs) outside the human body for clinical use in bone marrow transplantation -- a critical step towards producing a large supply of blood stem cells needed to restore a healthy blood system.

25 Mar 2013

$Immune system responds to fracture in similar way as to infection$

Immune system responds to fracture in similar way as to infection

Researchers at Charité - Universitätsmedizin Berlin have succeeded in demonstrating an association between delayed bone fracture healing and increased concentration of specific immune cells in the blood of the patient.

25 Mar 2013

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

During the past 30 years, the number of patients with cancers that originate near the junction of the esophagus and stomach has increased approximately 600 percent in the United States. The first extensive probe of the DNA of these esophageal adenocarcinomas has revealed that many share a distinctive mix-up of letters of the genetic code, and found more than 20 mutated genes that had not previously been linked to the disease.

25 Mar 2013

New guidance highlights risk factors and treatments for osteoporosis in postmenopausal women

A new Guidance recently published by the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) and the International Osteoporosis Foundation (IOF) reflects the most current advances in the diagnosis and management of osteoporosis, the 'silent disease' which affects up to one in two postmenopausal women.

25 Mar 2013

Healthy lifestyle may help prolong lives of individuals with chronic kidney disease

Certain lifestyle factors—such as not smoking, getting regular physical activity, and avoiding a low body weight—may help prolong the lives of individuals with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

25 Mar 2013

WSU researchers receive grant to examine effect of fatigue on decision making, attention

A team of researchers at Washington State University has received a three-year, $895,558 grant from the U.S. Department of Defense's Office of Naval Research to study the effects of fatigue on attention, decision making and their underlying biology.

25 Mar 2013

Researchers develop new device to battle against secondhand tobacco smoke

Dartmouth researchers have taken an important step in the ongoing battle against secondhand tobacco smoke. They have pioneered the development of a breakthrough device that can immediately detect the presence of secondhand smoke and even third-hand smoke.

25 Mar 2013

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

The over-the-counter anti-inflammatory drug naproxen may also exhibit antiviral activity against influenza A virus, according to a team of French scientists. The finding, the result of a structure-based investigation, is published online ahead of print in the journal Antimicrobial Agents and Chemotherapy.

25 Mar 2013

To stop mother-to-child transmission of HIV, focus on safe breastfeeding strategies

"There is great hope that we can finally stop infants from getting infected with HIV by their mothers. But first, countries with high rates of HIV infection must work out how to deliver reliable health programs to protect babies form their mothers' infected breastmilk," Pierre Barker, senior vice president of the Institute for Healthcare Improvement, writes in the Huffington Post's "Global Motherhood" blog.

25 Mar 2013

Certain strains of lactobacillus bacteria can dampen production of toxic shock syndrome toxin 1

Certain Streptococci increase their production of toxic shock syndrome toxin 1, sometimes to potentially dangerous levels, when aerobic bacteria are present in the vagina. But scientists from the University of Western Ontario have discovered certain strains of lactobacillus bacteria are capable of dampening production of that toxin according to research published in the journal Applied and Environmental Microbiology.

25 Mar 2013

Scientists call for leaders to combine poverty, environmental goals

Writing in the journal Nature, 10 scientists from around the world "say the only chance of achieving global prosperity is for all countries to combine poverty and environmental targets," and they ask "[w]orld leaders [to] set six goals around universal clean energy, an end to water and food shortages, thriving lives and livelihoods, and healthy and productive ecosystems," the Guardian reports.

25 Mar 2013

Protein with key job in muscle function moonlights in nucleus to help regulate genes

A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.

25 Mar 2013

Medical News

First Edition: March 25, 2013

Newly discovered molecule could form the basis of anti-malaria drugs

Actavis settles patent litigation with AstraZeneca over generic version of Crestor

Study shows why certain drugs that interact with serotonin receptors have harmful effects

Konzo's harm goes beyond devastating physical effects

MIT biology professor named Pew's Biomedical Researcher of the Month

Scientists identify potential treatment for idiopathic pulmonary fibrosis

Researchers study gene variants that bear signature for inflammatory disease susceptibility

Researchers expand hematopoietic stem cells for bone marrow transplantation

Immune system responds to fracture in similar way as to infection

Research may offer clues to why esophageal adenocarcinomas rates have increased rapidly

New guidance highlights risk factors and treatments for osteoporosis in postmenopausal women

Healthy lifestyle may help prolong lives of individuals with chronic kidney disease

WSU researchers receive grant to examine effect of fatigue on decision making, attention

Researchers develop new device to battle against secondhand tobacco smoke

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

To stop mother-to-child transmission of HIV, focus on safe breastfeeding strategies

Certain strains of lactobacillus bacteria can dampen production of toxic shock syndrome toxin 1

Scientists call for leaders to combine poverty, environmental goals

Protein with key job in muscle function moonlights in nucleus to help regulate genes

Voltammetry and machine learning for real-time neurotransmitter detection

How real-time off-gas analysis improves fermentation process control

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

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