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UHCC researchers identify role of RSK2 protein in cancer cell migration

Researchers at the University of Hawai'i Cancer Center have uncovered a novel mechanism that may lead to more selective ways to stop cancer cells from spreading. Associate Professor Joe W. Ramos PhD, a cancer biologist at the UH Cancer Center and his team have identified the role of the protein RSK2 in cancer cell migration, part of the process of cancer metastasis.

27 Feb 2013

Protective services workers more likely to develop psychiatric disorder after traumatic events

Police, firefighters and other protective services workers who are repeatedly exposed to traumatic events and are new to their profession are at greater risk of developing a psychiatric disorder, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

26 Feb 2013

XBiotech to enter biosimilar business

XBiotech, a privately held biotechnology company, announced today that it is entering the biosimilar business. The Company is launching its biosimilar business with development of two of the world's leading therapeutic antibodies, one an oncology and the other an anti-inflammatory product.

26 Feb 2013

Baxter files FEIBA NF BLA with FDA for prophylactic treatment of hemophilia A or B

Baxter International Inc. today announced that the company has submitted a biologics license application (BLA) supplement to the U.S. Food and Drug Administration (FDA) for the approval of prophylaxis treatment of FEIBA NF [Anti-Inhibitor Coagulant Complex], Nanofiltered and Vapor Heated, in patients with hemophilia A or B and inhibitors.

From Baxter International Inc. 26 Feb 2013

Genetic variation in CD33 influences how AML patients' leukemic cell responds to GO

Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia (AML) patients will benefit or not benefit from one of the newest antileukemic agents.

26 Feb 2013

IFR, PBL to further develop Dynamic Gastric Model

The Dynamic Gastric Model, developed from years of research at the Institute of Food Research, has taken significant steps towards improving its commercial use by food and drug companies worldwide.

26 Feb 2013

Shionogi receives FDA approval for Osphena to treat women with severe dyspareunia

The U.S. Food and Drug Administration today approved Osphena (ospemifene) to treat women experiencing moderate to severe dyspareunia (pain during sexual intercourse), a symptom of vulvar and vaginal atrophy due to menopause.

26 Feb 2013

Viewpoints: GOP faces pressure from spending cuts effects on daily life; President needs to lead on Medicare cuts

Cuts this draconian have no place in a tottering economy. But, realistically, the only way to break this standoff is for the cuts to exact their toll on daily life, causing Republicans to face pressure from the public to negotiate an alternative plan with higher revenues in March as part of talks to finance the government for the final six months of the fiscal year.

26 Feb 2013

Trends in patient worry and risk-reducing behaviors in women undergoing breast cancer treatment

Women who have had the lymph nodes under their arm surgically removed during breast cancer treatment are warned to avoid certain practices that can cause lymphedema-a condition that causes chronic, painless swelling in the arm.

26 Feb 2013

Nigeria launches 'NTD Master Plan'

Last week, "Nigeria launched a multi-year national plan for the control and elimination of neglected tropical diseases (NTD Master Plan)," which "provides a platform for Nigeria to stimulate global efforts to reach elimination and control of diseases under the London Declaration and Millennium Development Goal 6," Mawish Raza, communications intern for the Global Network for Neglected Tropical Diseases (NTDs), writes in the group's "End The Neglect" blog.

26 Feb 2013

Breakthrough study aims at developing first comprehensive model of fetal heart

Technology developed at The University of Nottingham has been used in a breakthrough study aimed at developing the first comprehensive model of a fully functioning fetal heart.

26 Feb 2013

U.N. must do more to fight cholera in Haiti

Noting U.N. Secretary-General Ban Ki-moon last week cited diplomatic immunity in "reject[ing] a legal claim for compensation filed in 2011 on behalf of cholera victims in Haiti," Louise Ivers, a senior health and policy adviser at Partners In Health, writes in a New York Times opinion piece, "Regardless of the merits of this argument, the United Nations has a moral, if not legal, obligation to help solve a crisis it inadvertently helped start."

26 Feb 2013

Conference aims to end tobacco epidemic in developing nations

Imagine, for a moment, that a plague has ravaged the Developed World, but has not yet established its grip on the Developing Nations. If the world's leaders in public health came together for two days at Harvard to map out a campaign to prevent the plague's spread, wouldn't you want to cover that meeting?

26 Feb 2013

Examining potential changes to U.S. food aid programs

"There are rumors that U.S. food aid programs could see major changes in the next budget, including converting some of the Food for Peace program into straight cash grants instead of in-kind food assistance," Roger Thurow, senior fellow of global agriculture and food policy at the Chicago Council on Global Affairs, writes in the group's "Global Food for Thought" blog.

26 Feb 2013

Societies advocate some change for colonoscopy patients with Medicare

The federal government has issued an important clarification on preventive screening benefits under the Affordable Care Act. Patients with private insurance will no longer be liable for cost sharing when a pre-cancerous colon polyp is removed during screening colonoscopy.

26 Feb 2013

Govs brace for impact of scheduled cuts in home states

The nation's governors met in Washington over the weekend, and among their hottest topics: a White House warning regarding the state-by-state impact of sequestration, which is scheduled to kick in March 1.

26 Feb 2013

Prime Time can lead to long-term reductions in sexual risk among vulnerable youth

More consistent use of condoms, oral contraception or both was reported by a group of teenage girls who took part in a youth development intervention aimed at reducing pregnancy risk in high-risk adolescents, according to a report of a randomized controlled trial published Online First by JAMA Pediatrics, a JAMA Network publication.

26 Feb 2013

Polio eradication strategy must be adjusted for local contexts

"It has been a particularly busy couple of months for the Global Polio Eradication Initiative (GPEI)," SciDev.Net Director Nick Ishmael Perkins writes in a SciDev.Net editorial. "The deadly attacks on vaccinators in Pakistan brought renewed global attention to the campaign, and then Bill Gates went public with his personal commitment to end polio," he states, adding, "The GPEI has responded with a strategy for what it calls the 'endgame.'"

26 Feb 2013

Surgeons told to pull the plug on robotically assisted hysterectomy

US researchers are calling for curbs on the rapidly increasing use of robotically assisted hysterectomy after an extensive study of the technique showed that it fails to improve outcomes over laparoscopy.

26 Feb 2013

Reduced income lessens chances of at-home death

Terminally ill patients with a low median annual household income are less likely to die at home than their wealthier counterparts, according to US study results published in JAMA Internal Medicine.

26 Feb 2013