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COPD benzodiazepine warning

Canadian researchers have found that benzodiazepines are frequently prescribed for patients with chronic obstructive pulmonary disease (COPD), despite their known association with adverse respiratory outcomes.

26 Feb 2013

Direct approach speeds ventilator weaning

Moving straight to unassisted breathing through a tracheostomy collar results in faster weaning than does a gradual reduction in pressure support among patients needing prolonged mechanical ventilation, shows a randomized trial in JAMA.

26 Feb 2013

Cognitive impairments in bipolar disorder 'stable'

Impaired cognitive function among bipolar disorder patients seems to be stable over time, suggesting it is an enduring feature of the condition, show the results of a longitudinal study.

26 Feb 2013

Depression links PTSD to life quality in bipolar disorder

The association between post-traumatic stress disorder and mental health-related quality of life among individuals with bipolar disorder may be mediated by depressive symptoms, the results of a US study indicate.

26 Feb 2013

Radial forearm free flap shows worth in mandibular reconstruction

The osteocutaneous radial forearm free flap should be used for mandibular reconstruction because of the low rate of long-term donor and recipient site complications, particularly with prophylactic plating of the donor radius, say US scientists.

26 Feb 2013

Natalizumab may be second-line option for pediatric MS patients

Natalizumab may be an effective and well tolerated second-line treatment for pediatric patients with highly active relapsing-remitting multiple sclerosis, say researchers.

26 Feb 2013

Loss of Dickopf-1 restores neurogenesis and memory in animal model

Loss of the molecule Dickopf-1 in the hippocampus in older animals increases neurogenesis, research shows.

26 Feb 2013

Cardiometabolic risk prevention opportunity in early schizophrenia

esearchers have found that cardiometabolic risk in patients with schizophrenia is heightened in those with established disease, suggesting a need for early intervention in those presenting with their first episode.

26 Feb 2013

Learned helplessness role in inflammatory polyarthritis revealed

Learned helplessness is a modifiable risk factor that can significantly influence disease outcome in patients with inflammatory polyarthritis, UK clinicians believe.

26 Feb 2013

‘Traffic light’ guide for pediatric bacterial infection needs refining

Study results suggest that a “traffic light” system for categorizing the severity of infections in children fails to detect a substantial number of serious bacterial infections, particularly urinary tract infections.

26 Feb 2013

Intense acupuncture shows promise for Bell’s palsy rehabilitation

Intense or “de qi” acupuncture produces significantly better results when added to prednisone treatment than low-intensity acupuncture for patients with Bell’s palsy, show findings from a randomized controlled trial.

26 Feb 2013

New handheld ultrasound device available from Signostics

Physicians now have access to an even faster and more accurate handheld ultrasound device, with Signostics today unveiling its new “Signos RT” model.

26 Feb 2013

Ill health more likely to be responsible for retirement in regional areas than in cities

Men and women of working age, living in regional areas are more likely to be fully retired because of ill health than their city counterparts, University of Sydney research shows.

26 Feb 2013

Two discriminating biological markers found to predict a favorable response to treatment in triple-negative breast cancer

Quinten, a strategic and operational consulting company specializing in the evaluation of biomedical data in the pharmaceutical, biotechnology and cosmetic industries, today announces the identification of two discriminating biological marker candidates which are indicative of a favorable response to treatment in women suffering from triple-negative breast cancer (TNBC).

26 Feb 2013

Pharmaceutical research centre led by the University of Limerick to receive investment from Science Foundation Ireland

A research centre led by the University of Limerick dedicated to supporting the pharmaceutical industry in Ireland will benefit from today’s announcement of €300 million investment by Science Foundation Ireland. The Irish pharmaceutical industry supports over 60,000 Irish jobs and exports over €50 billion annually.

26 Feb 2013

University of Alberta researchers help children with Down syndrome

Researchers from the University of Alberta are helping children with Down syndrome who stutter find their voice and speak with ease.

26 Feb 2013

Govs. Jindal, Walker offer views on averting sequester, reducing deficit

Louisiana Gov. Bobby Jindal suggested delaying implementation of parts of the health law. Wisconsin Gov. Scott Walker recommends focusing on paring back Medicare and Social Security spending.

26 Feb 2013

High-level results from AstraZeneca’s naloxegol Phase III trial on opioid-induced constipation

AstraZeneca today announced high-level results from KODIAC-08, an open-label, randomised, 52-week, long-term safety trial of naloxegol versus usual care (UC) in patients with non-cancer related pain and opioid-induced constipation (OIC). UC was defined as the investigator's choice of an existing laxative treatment regimen for OIC.

26 Feb 2013

Guardian podcast examines efforts to stop violence against women

In this Guardian "Global development podcast," Liz Ford, Guardian global development's deputy editor, speaks with Irene Khan, head of the International Development Law Organization; Korto Williams, country director of ActionAid Liberia; Andrew Long from the U.K. Foreign Office's prevention of sexual violence in conflict initiative; and Lakshmi Puri, deputy executive director of U.N. Women, about global efforts to stop violence against women.

26 Feb 2013

Researchers discover novel way to image the entire brain's glymphatic pathway

A novel way to image the entire brain's glymphatic pathway, a dynamic process that clears waste and solutes from the brain that otherwise might build-up and contribute to the development of Alzheimer's disease, may provide the basis for a new strategy to evaluate disease susceptibility, according to a research paper published online in The Journal of Clinical Investigation.

26 Feb 2013