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CELF6 genetic mutation may underlie common behaviors seen in people with autism

Scientists at Washington University School of Medicine in St. Louis have identified a genetic mutation that may underlie common behaviors seen in some people with autism, such as difficulty communicating and resistance to change.

14 Feb 2013

Targacept reports net loss of $15.9 million for fourth quarter 2012

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today reported its financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

Study identifies and discusses key factors that lead to obesity in pregnant women

A much neglected part of the obesity epidemic is that it has resulted in more overweight/obese women before and during pregnancy. Their offspring also tend to have higher birth weights and more body fat, and carry an increased risk of obesity and chronic diseases later in life. However, the nutritional factors and mechanisms involved pre and during pregnancy that may influence child obesity remain uncertain.

14 Feb 2013

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Lentigen Corporation, a biotechnology company specializing in the development and manufacture of lentiviral gene delivery products, announced today that that the U.S. Food and Drug Administration (FDA) has granted orphan drug status to P140K methylguanine methyltransferase (MGMT) transduced human CD34 cells for bone marrow protection in the treatment of glioblastoma multiforme.

14 Feb 2013

Weight Watchers International fourth quarter revenues increase 1.7% to $407.9 million

Weight Watchers International, Inc. today announced its fiscal 2012 results for the fourth quarter and full year and provided full year fiscal 2013 earnings guidance.

14 Feb 2013

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

Why does training in mindfulness meditation help patients manage chronic pain and depression? In a newly published neurophysiological review, Brown University scientists propose that mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms that help regulate how the brain processes and filters sensations, including pain, and memories such as depressive cognitions.

14 Feb 2013

New paper advances scientific understanding of glycoproteins’ structure and function

A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them.

14 Feb 2013

Triple-negative breast cancers more biologically diverse than previously believed

Triple-negative breast cancers are more biologically diverse than previously believed and classification should be expanded to reflect this heterogeneity, according to University of North Carolina researchers.

14 Feb 2013

ArthroCare fourth quarter total revenue increases 4.9% to $96.9 million

ArthroCare Corp., a leader in developing state-of-the-art, minimally invasive surgical products, announced its financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

Viewpoints: Obama prescription for Medicare is 'modest;' GOP doubts entitlement plan is serious

Somewhat more substantively, he called for a larger deficit-reduction deal built around loophole-closing tax reform and what he called "modest" reforms to Medicare and entitlements. In an apparent effort to rally Democrats to this cause, he called on "those of us who care deeply about programs like Medicare" to "embrace" reform.

14 Feb 2013

Updated Cochrane review on vitamin C and common cold

According to an updated Cochrane review on vitamin C and the common cold, vitamin C seems to be particularly beneficial for people under heavy physical stress. In five randomized trials of participants with heavy short-term physical stress, vitamin C halved the incidence of the common cold.

14 Feb 2013

DBS can lead to long-term improvement in patients with neuropathic pain

For many patients with difficult-to-treat neuropathic pain, deep brain stimulation (DBS) can lead to long-term improvement in pain scores and other outcomes, according to a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

14 Feb 2013

Tousled-like kinases play a key role in suppression and activation of herpesviruses

Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) hide within the worldwide human population. While dormant in the vast majority of those infected, these active herpesviruses can develop into several forms of cancer.

14 Feb 2013

FDA grants final approval to Breckenridge’s Pioglitazone Hydrochloride ANDA

Breckenridge Pharmaceutical, Inc. announced today the immediate launch of Pioglitazone Hydrochloride Tablets. The U.S. Food and Drug Administration granted final approval for the Abbreviated New Drug Application (ANDA), which is being manufactured and supplied by Synthon Pharmaceuticals, Inc., and will be available in 15 mg, 30 mg, and 45 mg strengths.

14 Feb 2013

TP PCR methodology may help streamline genetic testing for Huntington's

A new test may help to streamline genetic testing for Huntington Disease (HD) by generating accurate results, avoiding unnecessary additional testing, and improving turnaround time.

14 Feb 2013

Dyax fourth quarter total revenues increase to $16.0 million

Dyax Corp. today announced financial results for the fourth quarter and year ended December 31, 2012.

14 Feb 2013

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

Scioderm announced that the US Food and Drug Administration (FDA) has reviewed and allowed the investigational new drug (IND) application for SD-101 to proceed. SD-101 is a topical treatment being developed for the treatment of Epidermolysis Bullosa (EB).

14 Feb 2013

Blood’s tendency to clot may contribute to white matter hyperintensities in post-menopausal women

New Mayo Clinic research suggests that blood may hold clues to whether post-menopausal women may be at an increased risk for areas of brain damage that can lead to memory problems and possibly increased risk of stroke. The study shows that blood's tendency to clot may contribute to areas of brain damage called white matter hyperintensities.

14 Feb 2013

Violence against pregnant women in India contributes to high maternal mortality, the Atlantic reports

The Atlantic examines the issue of violence against pregnant women in India. "In the aftermath of the high-profile gang rape of a 23-year-old medical student, discussions have raged in India about the regularity of violence against women," the magazine writes, adding, "As has been widely noted, the causes of the violence run deep. But they also are broad."

14 Feb 2013

Medical News

CELF6 genetic mutation may underlie common behaviors seen in people with autism

Targacept reports net loss of $15.9 million for fourth quarter 2012

Study identifies and discusses key factors that lead to obesity in pregnant women

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

FDA grants orphan drug status to Lentigen’s LG631-CD34 for treatment of glioblastoma multiforme

Weight Watchers International fourth quarter revenues increase 1.7% to $407.9 million

Mindfulness practitioners gain enhanced control over sensory cortical alpha rhythms

New paper advances scientific understanding of glycoproteins’ structure and function

Triple-negative breast cancers more biologically diverse than previously believed

ArthroCare fourth quarter total revenue increases 4.9% to $96.9 million

Viewpoints: Obama prescription for Medicare is 'modest;' GOP doubts entitlement plan is serious

Updated Cochrane review on vitamin C and common cold

DBS can lead to long-term improvement in patients with neuropathic pain

Tousled-like kinases play a key role in suppression and activation of herpesviruses

FDA grants final approval to Breckenridge’s Pioglitazone Hydrochloride ANDA

TP PCR methodology may help streamline genetic testing for Huntington's

Dyax fourth quarter total revenues increase to $16.0 million

FDA allows Scioderm’s SD-101 IND application for Epidermolysis Bullosa to proceed

Blood’s tendency to clot may contribute to white matter hyperintensities in post-menopausal women

Violence against pregnant women in India contributes to high maternal mortality, the Atlantic reports

Fourier 80: bringing benchtop NMR systems to the laboratory

How industrial hygiene flow calibration supports defensible exposure data

How electrical engineering ensures accurate calibration and patient safety

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