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Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD).

8 Mar 2013

Animal robots help treat dementia

Proving the benefits and cost-effectiveness of animal robots in the treatment of dementia is the focus of a Griffith research study.

8 Mar 2013

Reduced visual sensitivity seen with use of multifocal intraocular lenses

Recent study findings indicate that eyes with multifocal intraocular lenses implanted during cataract surgery may develop reduced visual sensitivity.

8 Mar 2013

Addiction risk increased after mild traumatic brain injury

A study of military personnel suggests that individuals who have suffered a mild traumatic brain injury are at increased for addiction-related disorders.

8 Mar 2013

Artificial pancreas outperforms insulin pump in diabetes camp

An artificial pancreas system proved more effective at controlling nocturnal glucose levels than a sensor-augmented insulin pump, in a study of children with Type 1 diabetes treated outside the hospital setting in a diabetes camp, report researchers.

8 Mar 2013

IV iron dextran alternative to oral iron for anemia in nondialysis CKD

Treatment with intravenous low-molecular-weight iron dextran seems to be an effective alternative for patients with nondialysis chronic kidney disease who remain anemic despite receiving oral iron and erythropoiesis-stimulating agents.

8 Mar 2013

Halometasone and fusidic acid optimal for infected eczema

Results from a randomized, open-label phase III trial suggest that a combination cream of halometasone and fusidic acid reduces symptoms of eczema to a similar degree to a betamethasone and neomycin sulphate cream, but is more effective at treating infected lesions.

8 Mar 2013

Medication use and doctor visits drive up jaw necrosis-related costs

Long-term medication use and follow-up visits are the main drivers affecting costs associated with cancer-related bisphosphonate-associated osteonecrosis of the jaw, report researchers in Oral Diseases.

8 Mar 2013

Resuscitation with colloids not recommended

Resuscitation with colloids does not appear to decrease the risk for death, and may even increase mortality, a comprehensive study of trial data reveals.

8 Mar 2013

AKAP protein alterations implicated in bipolar disorder

Researchers have found increased cellular expression of the postsynaptic signaling protein AKAP5/79 in the anterior cingulate cortex of patients with bipolar disorder.

8 Mar 2013

Inflammatory marker for schizophrenia treatment resistance, severity

Levels of the inflammatory marker soluble tumor necrosis factor receptor 1 may be associated with severity of symptoms and treatment resistance in schizophrenia, say Brazilian scientists.

8 Mar 2013

Pharmacist-led intervention combats hypertension

A home-based intervention led by clinical pharmacists and involving an internet monitoring tool results in marked reductions in blood pressure, say researchers.

8 Mar 2013

Experience shows in febrile neutropenia treatment

The strongest predictors of guideline-compliant care of cancer patients with febrile neutropenia are the case volumes of the treating physicians and hospitals, a study shows.

8 Mar 2013

Femoral canal change detected in women over time

Women experience a gradual expansion in femoral canal diameter with increasing age, which could impact the longevity of total hip replacement, UK researchers report. age, which could impact the longevity of total hip replacement, UK researchers report.

8 Mar 2013