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Bipolar subtypes have differing personality traits

Results from a Korean study show how personality trait patterns differ between patients with bipolar I and II disorder.

28 Dec 2012

Sweet solution dulls needle pain in infants

Giving infants small amounts of sugar solution may reduce the pain they feel during injections, show results from a Cochrane systematic review.

28 Dec 2012

Make palliative care available to Parkinson's patients

A modified version of the Edmonton Symptom Assessment System Scale is quick and effective at assessing patients with late-stage Parkinson's disease, and reveals that they have similar levels of symptoms as their peers with metastatic cancer, show study results from Canada.

28 Dec 2012

Structure, training support reliable telestroke service

Clinically relevant misinterpretation of computed tomography images via telemedicine is rare in a system that uses a structured assessment of images, say German researchers.

28 Dec 2012

Translating calories to miles prompts significant portion reductions

Food labels that translate the number of calories in a meal into the amount of miles a person would have to walk to burn off those calories may be the most effective for reducing calorie intake, show study findings.

28 Dec 2012

Concern over transfusions in myocardial infarction patients

A meta-analysis highlights the consistent observational finding that patients with myocardial infarction who receive blood transfusions are at high risk for dying.

28 Dec 2012

Uncharacterized TLR plays key role in Toxoplasma gondii response

A previously uncharacterized toll-like receptor appears to play a crucial role in the innate immune response to Toxoplasma gondii infection and may promote host resistance, potentially leading to anti-parasite vaccines, say US researchers.

28 Dec 2012

Diabetes interventions show promise in primary care

Two lifestyle-based diabetes interventions developed in a clinical trial could successfully promote weight loss in primary care, research shows.

28 Dec 2012

Bumping up appendicitis diagnostic accuracy

It is well worth emergency doctors asking patients with abdominal pain how they were affected by driving over speed bumps on their way to hospital, research suggests.

28 Dec 2012

Ulcerative colitis impairs work capacity

Patients with ulcerative colitis have higher rates of sick leave or disability pension than the general population, show findings published in Gastroenterology.

28 Dec 2012

US acute kidney injury deaths ‘double in past decade’

A US study has found that the most severe form of acute kidney injury has increased nationwide by an average 10% per year with the number of associated deaths doubling over the past decade.

28 Dec 2012

Factors influencing anal sphincter injury risk ‘modifiable’

Researchers have identified several modifiable risk factors significantly associated with wound complications after obstetric anal sphincter injuries.

28 Dec 2012

Rhinosinusitis without nasal polyps ‘predisposes to psoriasis’

People who suffer from chronic rhinosinusitis without nasal polyps have around twice the risk for psoriasis as the general population, a Taiwanese study has found.

28 Dec 2012

Scientists identify molecular mechanism central to development of osteoarthritis pain

Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could have major implications for future treatment of this often-debilitating condition.

28 Dec 2012

Manipulating transcription factor can change subtype of breast cancer

Australian scientists have shown how a 'transcription factor' causes breast cancer to develop an aggressive subtype that lacks sensitivity to oestrogen and does not respond to anti-oestrogen therapies such as Tamoxifen and aromatase inhibitors.

28 Dec 2012

FDA clears Cepheid Xpert CT/NG molecular diagnostic test

Cepheid today announced that it has received clearance from the U.S. Food & Drug Administration to market Xpert CT/NG. Running on Cepheid's GeneXpert Systems, Xpert CT/NG is a qualitative in vitro molecular diagnostic test for the detection and differentiation of Chlamydia trachomatis and Neisseria gonorrhoeae. For the first time, same-day patient consultation and treatment is possible for the two most common sexually transmitted bacterial infections in the United States.

28 Dec 2012

Broader criteria for background checks can help prevent firearm violence

Garen Wintemute, a leading authority on gun violence prevention and an emergency medicine physician at UC Davis, believes broader criteria for background checks and denials on gun purchases can help prevent future firearm violence, including mass shooting catastrophes such as those that occurred at Sandy Hook, Aurora, Virginia Tech and Columbine.

28 Dec 2012

Hospitals that provide uncompensated care may undergo unintended cuts

The decision by several states not to expand Medicaid health insurance for the poor may create unintended cuts for hospitals that provide uncompensated care, according to a study by John Graves, Ph.D., a Vanderbilt policy expert in the Department of Preventive Medicine.

28 Dec 2012

Researchers study response of living cells to artificial protein

One approach to understanding components in living organisms is to attempt to create them artificially, using principles of chemistry, engineering and genetics. A suite of powerful techniques-collectively referred to as synthetic biology-have been used to produce self-replicating molecules, artificial pathways in living systems and organisms bearing synthetic genomes.

28 Dec 2012

PCORI research award to explore integration of patient strengths in treatment

Case Western Reserve University has been approved for a research award from the Patient-Centered Outcomes Research Institute (PCORI) to study ways that applying patients' strengths can help enhance their health care and well-being. The project is part of a portfolio of patient-centered comparative clinical effectiveness research that addresses PCORI's National Priorities for Research and Research Agenda.

28 Dec 2012