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Mount Sinai to initiate immunological therapy trial against chronic pulmonary sarcoidosis

Patients are currently being enrolled in the first clinical trial to investigate the efficacy of immunological therapy for chronic pulmonary sarcoidosis. The trial is being conducted by researchers at the Icahn School of Medicine at Mount Sinai.

31 Jan 2013

No proof of added benefit from aclidinium bromide in adults with COPD

The drug aclidinium bromide has been approved since October 2012 for widening the narrowed airways of adults with chronic-obstructive pulmonary disease (COPD). The German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined the added benefit of the drug pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG).

31 Jan 2013

Mayo Clinic cardiologists offer simple tips to reduce risk of heart disease

February is American Heart Month, a perfect time to remind people that small steps can reduce their risk of heart disease, the No. 1 killer of men and women. Mayo Clinic cardiologists offer several simple tips to reduce the risk.

31 Jan 2013

Libya becomes the first country to use Masimo Pronto-7 hemoglobin spot-check device

Masimo announced today that Libya has become the first country to begin using the Masimo Pronto-7— a handheld noninvasive hemoglobin spot-check device — to screen potential blood donors for low hemoglobin level in all of its major blood-donation centers.

31 Jan 2013

Potty training right from the birth can eliminate need for diapers

Western babies are potty trained later these days and need diapers until an average of three years of age. But even infants can be potty trained. A study by researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, followed 47 infants and their mothers in Vietnam - where potty training starts at birth and the need for diapers is usually eliminated by nine months of age.

31 Jan 2013

Study illuminates the response of dopaminergic neurons to changes in temperature

While the wooly musk ox may like it cold, fruit flies definitely do not. They like it hot, or at least warm. In fact, their preferred optimum temperature is very similar to that of humans-76 degrees F.

31 Jan 2013

Biomaterials as neural stem cell niches can help repair damage in the CNS

Despite recent advances in understanding the mechanisms of nerve injury, tissue-engineering solutions for repairing damage in the central nervous system (CNS) remain elusive, owing to the crucial and complex role played by the neural stem cell (NSC) niche. This zone, in which stem cells are retained after embryonic development for the production of new cells, exerts a tight control over many crucial tasks such as growth promotion and the recreation of essential biochemical and physical cues for neural cell differentiation.

30 Jan 2013

Top ten tips for keeping bed bugs at bay

Bed bugs are on the rise and $1,000 per day ordinances are being suggested in cities like Chicago to enforce combat of the pests. "Know thy enemy," says Jorge Parada, MD, medical director, infection control, Loyola University Health System. "There are lots of myths out there about bed bugs and people may be getting caught up over nothing."

30 Jan 2013

Androgens could constitute an efficient treatment against multiple sclerosis

Testosterone and its derivatives could constitute an efficient treatment against myelin diseases such as multiple sclerosis, reveals a study by researchers from the Laboratoire d'Imagerie et de Neurosciences Cognitives, in collaboration in particular with the "Neuroprotection et Neurorégénération: Molécules Neuroactives de Petite Taille" unit.

30 Jan 2013

IL-13 protein could be the key to development of fibrosis in Crohn's disease

New research has shown that a protein, known as IL-13, could be the key to the development of fibrosis in Crohn's disease. This breakthrough could help to advance new medicines to treat people suffering with the disease.

30 Jan 2013

No added benefit from perampanel in patients with epileptic fits

The drug perampanel has been approved since July 2012 as adjunctive therapy for adults and children aged 12 years and older with epileptic fits (seizures).

30 Jan 2013

MiR-182 deeply involved in memory formation within the amygdala brain structure

It takes a lot to make a memory. New proteins have to be synthesized, neuron structures altered. While some of these memory-building mechanisms are known, many are not. Some recent studies have indicated that a unique group of molecules called microRNAs, known to control production of proteins in cells, may play a far more important role in memory formation than previously thought.

30 Jan 2013

Keryx prices underwritten public offering of common stock

Keryx Biopharmaceuticals, Inc. today announced the pricing of its previously announced underwritten public offering of common stock consisting of 8,234,000 shares at $8.49 per share.

30 Jan 2013

Obama administration expected to continue science and technology diplomacy agenda, SciDev.Net reports

"The Obama administration is expected to continue including science and technology (S&T) in its diplomacy agenda, according to interviews with a number of people recognized for their contributions to international science cooperation," SciDev.Net reports.

30 Jan 2013

Microscopic hematuria poor indicator for renal, bladder malignancy

The presence of microscopic levels of blood in the urine is unreliable as an indicator for renal or bladder cancer, report researchers.

30 Jan 2013

ALDH1 expression predicts outcome in node-negative rectal cancer

Expression of the cancer stem cell marker aldehyde dehydrogenase 1 is an independent predictor for poor prognosis in node-negative rectal cancer, researchers say.

30 Jan 2013

Hospitalists flag patient overload threat to safety

Two-fifths of US hospitalists say their average patient load exceeds safe levels at least monthly, according to a nationwide survey.

30 Jan 2013

Birthweight extremes influence psychotic symptom severity

Both high and low birthweight increase the severity of psychotic symptoms, particularly disorganized and negative symptoms, research indicates.

30 Jan 2013

Bipolar pedigree endophenotypes found

Researchers have found cognitive endophenotypes in a single extended family showing linkage of bipolar disorder to a risk locus on chromosome 4.

30 Jan 2013

Maternal diet, first-year housing affect foals' osteochondrosis risk

Mares that are fed a diet that includes or is solely comprised of concentrates during gestation are significantly more likely to produce foals that develop permanent osteochondrosis lesions compared with mares who are fed a diet of roughage alone, report researchers.

30 Jan 2013